Lantus injection solution 100units/ml sanofi treatment of diabetes (10ml)

Dosage form Bottle x 10ml
Specifications Insulin Glargine

Ingredient

Composition information	Content
Insulin Glargine	100 units/ml

Uses

Indications

Lantus medicine 100 IU/ml is indicated in the following cases:

Treatment of adults, teenagers and children 6 years of age and older suffers from diabetes when needing insulin treatment.

pharmacokinetics

No information.

Before taking Lantus injection solution 100units/ml sanofi treatment of diabetes (10ml)

How to use

Lantus is injected under the skin. In a certain area, each injection should choose a different injection site. Because of the extended impact time depending on the injection under the felt, Lantus is not used for intravenous injection because it can cause severe hypoglycemia. Carefully observe the vial before use. Use only if the solution is transparent, colorless, there is no solid particles and liquid as water.

Lantus does not need to be mixed before use. The syringe must not contain any other substance or other residue. Mixing or mixing with any preparation can change the effectiveness or as a precipitate and thus avoid it. Should record the first day of withdrawal on the label.

Dosage

Because the drug has a long -lasting effect, Lantus can be injected once a day at any time of the day but daily should be injected at a certain hour. The doctor will adjust the dose depending on the person and will guide where the Lantus injection is, whenever the blood sugar is needed and the urine test is required.

Lantus can be used with an insulin that has a short impact or anti -diabetic medication.

When being treated with insulin, the average or short acting to the Lantus regimen can adjust the basic insulin dose and adjust the diabetes with the accompanying diabetes (the dose and the time to use the short -acting insulin or similar medications that quickly act quickly or the dose of anti -diabetes pills).

When transferring from insulin nPH twice a day to Lantus injected once a day, the initial dose must decrease by 20% (compared to the total number of micro -microscopes of the insulin NPH per day), and then adjust the dose based on the response of the patient. Reducing the at least the at least compensated by increasing insulin at mealtime. Then adjust the dose again with each person.

As other insulin -similar drugs, patients taking high doses of insulin because human anti -insulin antibodies can improve insulin response thanks to Lantus. Metabolic control, especially in these patients, should be closely monitored in the transition period and in the first weeks. And the improvement of metabolic scrambles and consequences is to increase insulin sensitivity (reducing insulin demand), may need additional dose for Lantus and other insulin or other anti -diabetes drugs in the regimen, may need further dose. The dose adjustment is also necessary in case of changing weight or lifestyle, changing insulin injection hours or cases that increase the infection with hypoglycemia or hyperglycemia or accompanying disease.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Mild hypoglycemia can usually be treated by oral carbohydrates. The dose, diet or physical activity may be required. More severe attacks with coma, convulsions or neurological disorders must be treated with glucagon (intramuscularly or subcutaneously) or glucose solution (intravenous infusion).

It is necessary to maintain the use of powder and prolonged monitoring because hypoglycemia may recur after clinical recovery.

What to do when forgetting a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Lantus 100 IU/ml, you may experience unwanted effects (ADR).

Hypoglycemia may occur if insulin dose exceeds the need. A significant change in blood sugar levels can cause transient visual disorders. Fatty tissue subcutaneously may be atrophy or hypertrophy in the injection site and slow down the absorer absorption and the effect of the drug will be slower. Choosing an injection site for each injection may decrease or prevent these reactions.

Other reactions include: redness, more pain than usual when injecting, itching, urticaria , swelling or inflammation. Those reactions are usually lost in a few days to a few weeks.

Some rare cases, severe allergic reactions may occur.

Other reactions

Insulin injection can form anti -insulin antibodies.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Lantus 100 IU/ml contraindications in the following cases:

allergies to insulin glargine or any excipients of the drug.

Precautions when using

Patients need to be instructed on the skills necessary to handle diabetes by diabetes such as blood sugar monitoring, proper injection of drugs, measures to identify increased or decreased blood sugar. In addition, patients need to practice dealing with special situations such as dosage, insulin dose is not enough or too high, incomplete eating or skipping meals.

In case of unsatisfactory blood glucose control or tend to occur blood sugar or hyperglycemia, it is necessary to eliminate potential factors (such as the patient's compliance with the patient, the selection of the injection and the right injection) before considering the dose adjustment.

Because of limited experience. It is impossible to evaluate the effectiveness and safety of Lantus in children under 6 years old, on patients with liver function, or patients with kidney failure from moderate to severe.

In patients with renal failure, insulin needs may decrease. On the elderly, the impairment of kidney function can lead to reduced insulin demand. In patients with severe liver failure, insulin demand may be reduced due to reduced ability to produce sugar and reduce insulin metabolism.

The ability to drive and operate machinery

As a result of hypoglycemia, hyperglycemia or visual disorders, the ability to concentrate and the reaction may be affected, may become a risk in special situations that need these capabilities (for example driving or operating machine).

Pregnancy

in diabetes before or during pregnancy, it is necessary to maintain good control of metabolism during pregnancy. In the first 3 months, insulin demand usually decreases, but usually increases in the middle and the last 3 months. Immediately after birth, insulin demand decreases rapidly (increasing the risk of hypoglycemia) so it is necessary to carefully monitor blood sugar.

Breastfeeding period

In women breastfeeding with breast milk, it is necessary to adjust the dose and diet.

Medicinal interaction

Some images of glucose metabolism and need to adjust and monitor closely. Increasing hypoglycemia and increased sensitivity to hypoglycemia may occur when using anti -diabetic tablets, enzyme inhibitors, disopyramide, fibrate, fluoxetine, Mao inhibitors, pentoxifylline, propoxyphene, salicylate, or sulfonamide antibiotic.

Reducing hypoglycemic effects may occur when used with corticosteroids, danazol, diazoxide , diuretic, glucagon, isoniazide , estrogen and progestogen (for example of contraceptives), phenothiazine derivatives, Somatropin, sympathetic drugs (such as Epinephrine, Salbutamol, Salbutamol, Salbutamol, Salbutamol, Salbutamol, Salbutamol, Salbutamol, Salbutamol, Salbutamol, Salbutamol, Salbutamol, Salbutamol, Salbutamol, Salbutamol, Salbutamol, Salbutamol terbutaline) or thyroid hormone.

Beta, clonidine, lithium or alcohol blockers can enhance or weaken the effect of insulin's blood sugar.

Pentamidine can cause hypoglycemia, sometimes followed by hyperglycemia. Moreover, Chen Beta is as well as other sympathetic blockers (such as Clonidine.

Storage

Store the drug in the base box to avoid light. Do not allow frozen, remove drugs that have been frozen. Do not leave Lantus next to the freezer or stone blister in the refrigerator.

Store before opening at 2 ° C to 8 ° C. If you take the vial out of the linen storage conditions can be held at +30 ° C to 4 weeks. The vial after opening, whether it is refrigerated or does not have to be removed after 28 days.

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