Lantus Solostar 100 Units/ml for diabetes treatment (5 trees x 3ml)
Dosage form Box of 5 trees x 3ml
Specifications Insulin Glargine
Ingredient
| Composition information | Content |
| Insulin Glargine | 100 units/ml |
Uses
Indications
Lantus solonal injection pen used in the treatment of diabetes in adults, teenagers and children aged 6 and older.
Pharmacokology
Pharmacological group: anti -diabetes drugs, insulin and similar substances injected, long effects.
ATC code: A10A E04.
Insulin Glargin is a human insulin similar substance designed for low solubility in neutral pH. The drug is completely dissolved in the acid pH of the Lantus injection solution (pH 4). After injecting into subcutaneous tissue, this acidic solution is neutralized to the formation of micro -precipitates so that thereby continuous release of small amounts of insulin glargin, providing a concentration of drugs over time, without vertices, can be predicted, with a long impact time.
Insulin receptor conclusion: Insulin Glargin is quite similar to human insulin in terms of kinetics. Therefore, it can be considered as an intermediary for the same type of effect like insulin insulin receptor.
The main activity of insulin, including glargin insulin, is to regulate glucose metabolism. Insulin and its similar substances lower blood glucose levels by stimulating peripheral glucose, especially in muscular and fat, and by inhibiting the production of glucose in the liver. Insulin inhibits fat in fat cells, inhibits protein resolution and enhances protein synthesis.
In clinical pharmacological studies, insulin glargin and intravenous insulin are shown to have equal activity when using the same dose. Like all other insulin, the impact time of insulin glargin may be affected by physical activity and other variables.
In the studies of glucose transmission stable blood sugar on healthy subjects or on patients with type 1 diabetes, the impact of insulin glargin subcutaneously slower than human insulin, its effects are less fluctuating and no top, and prolonged impact time.
pharmacokinetic pharmacokinetics
on healthy objects and patients with diabetes, serum insulin concentration proves a slower and longer absorption and does not see the peak after injection under the Insulin Glargin compared to NPH insulin. Thus, the concentration is consistent with the time characteristics of pharmacological activity. The above chart shows the activity of insulin glargin and NPH insulin over time.
Insulin glargin inject once a day will reach the concentration at a stable state in the first 2-4 days after the first dose.
When intravenously, the sale time of insulin glargin and insulin is similar. On humans, the insulin glargin is partially decomposed in the subcutaneous tissue at the tip of the carboxyl of the beta chain with the formation of active metabolites 21A-Gly-Insulin and 21A-Gly-Des-30B-Thr-Insulin.
Insulin glargin is unchanged and the decomposition products are also present in plasma. In clinical studies, age and gender group analysis does not show any difference in safety and effectiveness in patients treated with insulin glargin compared to the entire research complex.
Before taking Lantus Solostar 100 Units/ml for diabetes treatment (5 trees x 3ml)
How to use
Lantus injection pen is injected under the skin, not injected Lantus into the vein because the effect of the drug will be changed and can cause hypoglycemia.
The doctor will tell you which skin should be injected. Each injection should change the injection site on the selected skin area.
Solostar is a ready -to -bes containing insulin glargin and then removed.
Must attach a new needle before each injection. Only use needles compatible with solostar.
Must be tested safely before each injection.
Before using a pen, need to carefully review the drug compartment. If there are pork seeds, you should not use a pen. Use only Lantus 100iu/ml injectable pen if the solution is clear, colorless and like water. Do not shake or mix the medicine before use.
To prevent infections transmission, each pen is only used for one patient. If asking other people to help, this person must be particularly cautious to avoid accidentally being needed and contagious.
Make sure that insulin is not contaminated with alcohol or other antiseptic drugs, or other substances.
Always use a new pen to see if the blood sugar control is out of expected. If there is a problem, there is a problem when using the Lantus Solostar injection pen should ask the doctor again.
Do not recover the drug in an empty injection pen but must cancel properly.
Do not use the Lantus Solostar pen to use if it is damaged or does not meet the requirements, but must cancel and use a new pen. There must always be a Lantus 100iu/ml injection pen in case the pen is broken or lost.
Instructions for use
Step 1: Check insulin.
a. Check the solostar pen label to make sure to use the correct type of insulin. Lantus Solostar pen is gray and purple injection button.
b. Remove the pen cap.
c. Check the sensory form of insulin. Lantus is a transparent insulin solution. Do not use the Lantus Solostar 100iu/ml injection pen if the insulin is cloudy, colored or has a pig seed.
Step 2: Mount the needle.
Always use a new, sterile needle, for each injection. This helps to avoid contamination and clogged.
a. Remove the protective seal of the new needle.
b. Leave the needle in line with the pen body, and keep the monkey straight (twist or press, depending on the type of needle). src = "https://lh3.googleuserccontent.com/vrxh-j8pomxumqsq4yixjapzwenu-98tmrowadvfzxmixrehreh SI5SU-XS-DSRS7VLES4BSNDI3XVLBY9CNCABQXGYW-2SX6X5SX5SPC08FTDMLM0CR1PTTU6OV925xOZDK = S0 ">
Leave the needle in line with the pen body, and still keep the monkeys directly (twist or press, depending on the type of needle).
If not holding the needle when attached, it can damage the rubber mattress and cause leakage, or broken needle.
Step 3: Safe test.
always do a safe test before each injection. This helps you get the right dose by:
b. Remove the outer needle lid and hold it back to remove the needle after the injection is complete.
Remove the inner needle lid and throw away. src = "https://lh3.googleuserccontent.com/l_izmxgnhsny3b7uoptl0byacgnb42thvqxey0zdzwvgh0pnjj lsouazd1nhyblsvlbs61xsx7SCP_K4E_MWEDMXCG9KLESYO__JCEZZ8AX4JXUH317O_CFYM0ZTDLBJ = S0 ">
c. Hold the pen injected with the tip of the needle upwards.
d. Type the insulin chamber to push air bubbles on the needle tip.
e. Click all the depth of the injection button. Check if the insulin is pouring out at the tip of the needle.
may have to do a safe test several times to see the insulin.
Step 4: Select the dose.
You can choose the dose of one unit one, from the minimum of 1 unit to a maximum of 80 units. If the dose is needed greater than 80 units, it is necessary to divide in two or more injections.
a. The window check indicates the dose indicated that the number "0" after testing safely.
b. Select the dose to be used (for example, the selected dose is 30 units). If you accidentally overdose, you can turn back.
Step 5: Injecting drugs.
a. Use the injecting method of the doctor.
b. Metallic needles.
c. Press the button to inject all its depth. The number on the window will only return to "0" when injected.
d. Still hold the injection button. Count slowly to 10 before withdrawing the needle from the skin. This guarantees the entire medicine to be injected.
Step 6: Remove and cancel the needle.
After the injection, always need to remove the needle and store the pen injection pen without needles.
That helps to avoid:
If asking others to help, this person must be particularly cautious when removing and canceling the needle. Compliance with safety measures recommended when removing and canceling needles (for example, one hand -covered technique) to reduce the risk of needle and infectious diseases.
b. Cancellate needles safely, according to the instructions of the medical staff.
c. Always remember to cover the pen lid, then store the pen until the next injection.
Maintenance
Do not let the pen get dirty and dusty.
Can wipe the outside of the insulin lantus solon with wet fabric.
Do not dip water, wash or gest injected pen because it will damage the pen.
Solostar injection pens are designed to be effective and safe to inject, need light hands when manipulating. Avoid situations that can damage solostar injection pen. If you are afraid of a broken solostar injection pen, use a new injection pen.
Dosage
Based on lifestyle, blood sugar test results and your previous insulin use, the doctor will:
Determine how much lantus you need every day and use it.
Let you know when to check blood sugar levels and need urine tests or not.
Let you know when the Lantus injection is higher or lower.
Lantus is a long -acting insulin that can be used in combination with a short -acting insulin or anti -diabetes pill.
Time of drug use:
What to do when overdose? Please regularly check blood sugar. In general, to prevent hypoglycemia, you need to eat more food and monitor blood sugar. For information about hypoglycemic treatment, see the framed part at the end of this tutorial.
What to do when forgetting a dose? Please regularly check blood sugar. See information about blood sugar treatment in the framed part at the end of this tutorial.
Do not inject double the dose to compensate for the missed dose.
Stop using insulin Lantus: This can lead to severe hyperglycemia (very high blood sugar levels) and keton acidosis (accumulating acids in the blood because the body consumes fat instead of sugar). Do not arbitrarily stop using Lantus but must consult a doctor.
Side Effects
Common, ADR> 1/100
Metabolism: hypoglycemia.
Skin and subcutaneous tissue: Fatty disorder, skin reactions and allergies.
Rare, 1/10,000 Systemic: allergic reactions with insulin (rash, itching, skin edema and mucosa, shortness of breath, hypotension, increased heart rate, sweating). Eyes: visual disorders, temporary vision loss. Other: antibodies of insulin resistance, leg edema and ankle, taste disorders, muscle pain. Instructions on how to handle ADR When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.
Warnings
Contraindicated
Lantus injection pen contraindicated treatment in the following cases:
Precautions when using
Strictly follow the instructions on dosage, how to monitor (blood and urine test), diet, and physical activity (manual labor and exercise), injection techniques that the doctor has advised.
Special patient groups
There is little experience in using Lantus in children under 6 years old and patients with bad liver and kidney function.
When going abroad
Before you go, you should consult your doctor about:
The ability to earn an insulin type is used in the country to visit.
Insulin supply, syringe ...
Store insulin properly while going away.
Determine the meal time and the injection time while going.
The possible effects of changing time zone.
New health risks can be encountered in the country to visit.
What must be done in emergency situations when not feeling well or sick.
Sickness and injury
In the following situations, the treatment of diabetes must be very careful:
When sick or seriously injured, your blood sugar may increase (hyperglycemia).
If you eat incomplete, blood sugar may decrease too low (hypoglycemia). In most cases, you will need a doctor. It is necessary to make sure to contact the doctor soon.
If you have type 1 diabetes (insulin dependence), do not stop taking insulin and eat enough carbohydrates. Always have to notify the person who is caring or treating you know that you need insulin.
The ability to drive and operate machinery
The ability to focus and react may decrease if:
Hypoglycemia (low blood sugar levels).
Hyperglycemia (high blood sugar levels).
There is an vision problem.
Pay attention to this issue in all situations that can be dangerous for yourself or for others (for example driving or operating the machine). Should consult your doctor about driving if:
Or have hypoglycemia.
Decreased or showing signs of alerts of hypoglycemia.
Pregnancy
notify the doctor if you are intended to be pregnant or pregnant. Insulin dose should be changed during pregnancy and after childbirth. In particular, careful control of diabetes and prevent hypoglycemia is important for the baby's health.
Breastfeeding period
If breastfeeding, consult your doctor because you may need to adjust insulin and diet.
Drug interaction
Some drugs may change blood sugar levels (decrease, increase or both depending on the situation). In each case, insulin dose should be adjusted to avoid blood sugar too low or too high. Must be cautious not only when starting to take a drug but also when stopping taking the drug.
inform the doctor all the drugs you are taking, including those who buy without prescription. Before taking a drug, ask the doctor to see if it may affect blood sugar, and if any, what to do.
Medicines that can reduce blood sugar include all other diabetes medications, angiotensin transferring enzymes (treatment of heart disease or hypertension), disopyramid (heart disease treatment), fluoxetin (treatment of depression), fibrat (used to lower high lipid levels in blood), Monoamine oxidase inhibitors (Mao) (MA), used to treat depression), to be used to treat depression), to be used to treat depression), to be used to treat depression), to treat depression) Pentoxifyllin, Ropoxyphen, Salicylate (such as aspirin, are used to relieve pain and reduce fever), and sulfonamid antibiotics.
Medications that can increase blood sugar include corticosteroids (such as "cortisone" used to cure inflammation), Danazol (drugs affected on ovulation), diazoxid (used to treat hypertension), diuretics (used to treat hypertension or keep too much water), glucagon (pancreatic hormone is used to treat heavy blood sugar), ISONIAZID (used to treat tuberculosis) Estrogen and progestogen (such as birth control pills used in childbirth control), phenothiazine conductors (used to treat mental disorders), Somatropin (growth hormone), sympathetic drugs (such as Epinephrine [Adrenalin] or Salbutamol, Terbutalin used to treat asthma), thyroid hormones are used to treat glands to treat tips armor), typical anti -psychotic drugs (such as olanzapin and clozapin), protease inhibitors (used to treat HIV).
Blood sugar levels may increase or decrease if you are taking beta blockers (used to treat hypertension), clonidin (used to treat hypertension), lithium salt (used to treat mental disorders). Pentamidine (used to treat a number of parasitic infections) can cause hypoglycemia and sometimes followed by hyperglycemia. Beta blockers, as well as other sympathetic paralysis (eg clonidin, guanethidin and reserpin) can overshadow or completely inhibit the alert symptoms of hypoglycemic reactions.
Blood sugar levels may increase or decrease if you drink alcohol.
Storage
To be out of reach and eyes of children.
Unused injection pen
Store in the refrigerator (2 ° C - 8 ° C). Do not freeze.
Do not place Lantus Solostar near the freezer or ice blister in the refrigerator.
Keep the pen in the box to avoid light.
Injectable pen is in use
Pre -intensive pen is used or carried for storage can be preserved for up to 4 weeks at a temperature of not more than 30 ° C, avoiding heat and direct light.
Injectable pen is not stored in the refrigerator. Do not use the pen in the above time.
Do not destroy drugs through wastewater or domestic waste.
Instructions for storage
If solostar is refrigerated, it is necessary to remove it from the refrigerator for 1-2 hours before injection because the cold insulin injection is very painful.
Destroying the Lantus Solostar pen in accordance with health regulations.
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