Lastro 30mg hard capsules DHG Pharma treat esophagitis (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Lansoprazole

Ingredient

Composition information	Content
Lansoprazole	30mg

Uses

Indications

Lastro 30 drugs are indicated in the following cases:

Acute treatment and treatment for ulcerative esophagitis in patients with gastroesophageal reflux disease (up to 8 weeks).

Lastro contains the main component of the Lansoprazols that conducts benzimidazols that have an anti -gastric secretion effect, belonging to the proton pump inhibitor group. Lansoprazols are not inversely linked to H+/K+ ATPASE - is an enzyme system on the surface of the cell into the stomach into the stomach, thus inhibiting the transport of hydrogen ions into the stomach.

Lansoprazol is used for short -term treatment of gastric and duodenal ulcer and long -term treatment of hyperactive discharge of pathology (such as Zollinger - Ellison syndrome, endocrine multi -gland tumor, systemic nourishment). The level of stomach acid secretion depends on the dose and treatment time, but the Lansoprazole inhibits acid secretion better than H2 receptor antagonists.

Lansoprazol can prevent Helicobacter pylori in people with stomach ulcer - duodenum infected with this bacteria. If combined with one or more anti -bacterial drugs (such as amoxicillin, clarithromycin), Lansoprazol may be effective in exporing H. pylori.

pharmacokinetic pharmacokinetics

Lansoprazol absorbs fast, the maximum maximum concentration is reached in about 1.7 hours after drinking, absolute bioavailability of over 80%. In strong people, the sale time in plasma is 1.5 (± 1.0) hours. Both the maximum medication concentration and the area under the curve (AUC) decreased by about 50% if used for about 30 minutes after eating.

Lansoprazol binds to plasma proteins about 97%. About 20% of the drug is excreted into bile and urine. Therefore, the dose should be reduced for people with severe liver disease.

Before taking Lastro 30mg hard capsules DHG Pharma treat esophagitis (3 blisters x 10 tablets)

How to use

Take oral use.

Lansoprazol is not durable in acidic environment (gastric juice), so you must take Lansoprazol before eating and not bite or chew capsules.

Dosage

ulcerative esophagitis

Adults: 30mg (1 tablet) x 1 time/ day, for 4 - 8 weeks. Can be used for 8 more weeks, if not cured.

Stomach ulcer

30mg (1 tablet) x 1 time/ day, used for 4 - 8 weeks. Should drink in the morning before breakfast.

Used in combination with amoxicillin and clarithromycin in the treatment of H. pylori infection in patients with duodenal ulcerative active as follows:

Combining 3 drugs: 30mg (1 tablet) Lansoprazol + 1g amoxicillin + 500mg Clarithromycin, use 2 times daily, for 10 to 14 days. Drink before meals.

Combining 2 drugs: 30mg (1 tablet) Lansoprazol + 1g amoxicillin, use 3 times daily, for 14 days. Drink before meals.

Other acid secretion (Zollinger - Ellison syndrome)

Adults: The starting dose is 60mg (2 capsules) x 1 time/day. Should drink in the morning before meals.

Need to reduce the dose for people with severe liver disease, usually not exceeding 30mg/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms

Heat lower body, sedation, convulsions, respiratory frequency.

Support treatment

The method of separation does not eliminate the drug.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Lastro 30, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Body: headache, dizziness.

digestive: diarrhea, abdominal pain, nausea, vomiting, constipation, indigestion.

DA: rash.

Uncommon, 1/1000

Fatigue.

Rare, ADR

Subclinical: Increasing serum, liver enzyme, hematocrit, hemoglobin, uric acid and proteinuria.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Lastro 30 contraindications in the following cases:

Hypersensitivity to Lansoprazol or other ingredients of the drug.

Pregnant in the first 3 months.

Precautions when using

Dosage is needed for people with liver disease. Pregnant and lactating.

The ability to drive and operate machinery

Caution when driving and operating machinery because the drug can cause headaches, dizziness on some objects.

Pregnancy

It is not known if the drug will pass through the fetus into the fetus. However, long -term and high doses that have caused cancer on experimental animals, so it should be avoided for pregnant women, at least for the first 3 months, but it is best not to be used in any stage of pregnancy.

Breastfeeding period

Lansoprazol and metabolites may excrete through breast milk. Because the effect of cancer of the drug has been proven to be shown to avoid being used in nursing mothers.

Drug interaction

Lansoprazol is metabolized by the cytochrom P450 enzyme system, not to use Lansoprazols along with drugs metabolized by this enzyme.

lansoprazole reduces the effect of ketoconazole, itraconazole and other drugs with acidic absorption.

Sucralfat slowed down and reduced the absorption of Lansoprazol (about 30%).

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding light.

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