Lincomycin 600mg/2ml Siu Guan Chem treatment for respiratory infections, skin, soft tissue (10 tubes)

Dosage form Box of 10 tubes x 2ml
Specifications Lincomycin

Ingredient

Composition information	Content
Lincomycin	600mg

Uses

Indications

Lincomycin 600 mg/2 ml drug is indicated in the following cases:

Severe infections in the ear, nose, throat, bronchitis, skin infections, soft tissue and joints, genital tract infections.

Pharmacology

Lincomycin has anti -bacterial effects such as Clindamycin, but less effective.

The main drug grams of Gram -positive and wide antibacterial spectrum for anaerobic bacteria.

Mechanism of action: Lincomycin, as well as other lincosamids attached to the mini of the part of the bacterial ribosom like macrolids like erythromycin and hinder the first phase of protein synthesis. The main effect of Lincomycin is bacteria, but at high concentrations can kill slowly for sensitive strains.

Effect spectrum: The drug is effective for many Gram -positive bacteria, including Staphylococcus, Streptococcus, Pneumococcus, Bacillus Anthracis, Corynebacterium Diphtheriae. However, it does not work with Enterococcus.

Lincomycin has a broad spectrum for gas bacteria. Sensitive Gram -positive gas bacteria include eubacterium, propionibacterium, peptococcus, peptostreptococcus and many strains of Clostridium perfringens and CL. Tetani. With high doses, Lincomycin works for gram -negative bacteria, including Bacferoides spp. The drug also has a few effects on unicellular animals, so it has been tried in the treatment of pneumocystis carinii pneumonia and Toxoplasma infection. The minimum inhibitory concentration of lineomycin for the most sensitive bacteria strains range from 0.05 - 2 micrograms/ml.

Dynamic pharmacokinetics

Injecting 600 mg intramuscularly reaches the peak of plasma from 8 - 18 micrograms/ml for 30 minutes. Lincomycin's half life is about 5 hours. Lincomycin is distributed into tissues, including bone tissue and fluid but less into the cerebrospinal fluid, although it can be more distributed when the meninges are inflamed. The drug diffuses through the placenta and is found 0.5 - 2.4 micrograms/ml Lincomycin in breast milk. Lincomycin does not remove much from blood through the cup. Lincomycin is partially deducted in the liver and is exported in urine and feces, in the form of unchanged and metabolic form.

Before taking Lincomycin 600mg/2ml Siu Guan Chem treatment for respiratory infections, skin, soft tissue (10 tubes)

How to use

can be used in intriguing, or intravenous injection.

Can be intramuscularly or intravenously.

For intravenous transmission, mixed with 5% glucose solution or 0.9% sodium chloride solution on the basis of 1 g Lincomycin mixed into at least 100 ml of appropriate solution and drop drip at least 1 hour (100 ml/1 hour). Do not be injected directly into the vein.

For people with severe renal failure, the appropriate dose is 25 - 30% of the normal dose.

Dosage

intramuscularly

Adults: 600 mg (2 ml) 1 time for 24 hours; If very heavy: 600 mg (2 ml) 12 hours apart.

Children over 1 month of age: 10 mg/kg body weight, 1 time in 24 hours; If very heavy: 10 mg/kg body weight, 12 hours apart.

intravenous infusion

Adults: 600 mg - 1 g, 8 - 12 hours apart; If very heavy: maximum dose can be 8 g/24 hours.

Children over 1 month of age: 10 - 20 mg/kg/24 hours, depending on the severity of the disease and the same dose division as in adults.

Caution: Must reduce the dose for people with renal failure.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Lincomycin 600 mg/2 ml you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: Nausea, vomiting, diarrhea, sometimes due to too much development Clostridium difficile.

Uncommon, 1/1000

Skin: urticaria, rash.

Other effects: local response after intramuscular injection, thrombosis after intravenous injection.

Rare, ADR

Body: Anaphylaxis.

Blood: neutrophils (recovery). digestive: fake colitis, esophagitis during oral treatment.

liver: Increased liver enzyme (recovery), such as increased transaminase.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Lincomycin drug 600 mg/2 ml contraindicated in the following cases:

Hypersensitivity to Lincomycin or with medications with them with Lincomycin.

Be cautious when using

Must reduce the dose for people with kidney failure.

The ability to drive and operate machinery

can be used.

Pregnancy

There has been no Lincomycin notice that causes birth defects. The drug passes through the placenta and reaches about 25% of the mother serum concentration in the umbilical cord. Babies born have not yet been affected.

The period of breastfeeding

lincomycin is secreted in breast milk to the point where it is likely to adversely affect breastfeeding. Therefore, breastfeeding should be avoided while being treated with Lincomycin.

Drug interaction

Concomitant use of Lincomycin with neurotransmitter medications such as tuboCurarine and antibiotics that have the same toxicity such as:

colistin, streptomycin, neomycin, kanamycin, polymycin can lead to respiratory paralysis. Erythromycin has antagonistic effect with Lincomycin.

Storage

In a dry place, avoid light, the temperature does not exceed 30⁰C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.