Lincomycin injection solution 600mg/2ml Vinphaco treat bone and gynecological infections (1 blister x 10 tubes)

Dosage form Box of 1 blister x 10 tubes
Specifications Lincomycin

Ingredient

Thành phần cho 2ml

Composition information	Content
Lincomycin	600mg

Uses

indicated

lincomycin 600mg indicated treatment in the following cases:

Severe infections caused by sensitive bacteria, especially Staphylococcus, Streptococcus, Pneumococcus in patients with allergies to penicilin such as liver abscess; Bone infection caused by staphylococcus; Gynecological infections such as vaginal infections, uterine membrane inflammation, pelvic inflammatory disease; secondary peritonitis; lung abscess; Blood infection; Acne complications and ulcers due to anaerobic infections.

pharmacokinetics

No data.

Before taking Lincomycin injection solution 600mg/2ml Vinphaco treat bone and gynecological infections (1 blister x 10 tubes)

How to use

lincomycin 600mg of injection solution. Drugs can be intramusile or intravenous injection.

For intravenous transmission, mixed with 5% glucose solution or 0.9% sodium chloride solution with a concentration of 1 g of lincomycin mixed into at least 100 ml of appropriate solution and drip drops for at least 1 hour (100 ml/1 hour).

Do not be injected directly into the vein.

For people with severe renal failure, the appropriate dose is 25 - 30% of the normal dose.

Currently Clindamycin is more popular than Lincomycin, because of better absorption and effect. However, both drugs are used limited due to the risk of fake colitis.

Dosage

lincomycin injection is Lincomycin hydrochloride, but the dose is calculated according to the anhydrous lincomycin; 1.13 g Lincomycin hydrochloride is equivalent to 1.0 g lincomycin anhydrous

Adults: Intramuscularly 600 mg, 1 time or 2 times/day or slow intravenous injection 0.6-1.0 g, 2 times or 3 times/day. For severe bacterial infections, using an intravenous line is 8 g/day higher than the recommended dose of 8 g/day in this case, 1 g Lincomycin is diluted with no less than 100 ml of solvent and transmitted for at least 1 hour. The manufacturer recommends a 1g dose of 1 hour transmission, 2 g of transmission for 2 hours, a dose of 3 g in 3 hours, a dose of 4 g in 4 hours.

Children and children aged 1 month and older: Intravenous or intravenous injection 10 - 20 mg/kg/day, divided into several times.

Lincomycin can be given injected under the conjunctiva at a dose of 75 mg.

Dosage for people with renal failure: Reducing the dose for people with severe renal failure, appropriate dose equal to 25-30% of normal dose.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

Unwanted effects (ADR) when using Lincomycin 600mg that you may encounter:

The most common unwanted effect is in the gastrointestinal tract, mainly diarrhea.

Common, ADR> 1/100

Digestive: Nausea, vomiting, diarrhea, sometimes due to too much development Clostridium difficile.

Skin: urticaria, rash.

Systemic body: Anaphylaxis reaction. for the doctor or the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Lincomycin 600mg contraindications in the following cases:

Hypersensitivity to Lincomycin or with the same drugs as Lincomycin or with any ingredients in the preparation.

Caution when using

must be cautious when used for people with gastrointestinal diseases, especially people with a history of colitis. Elderly and female patients may be susceptible to severe diarrhea or fake colitis.

Be careful for people with allergies, people with liver failure or severe kidney failure. For these people, the dosage must be adjusted accordingly. For patients with long -term treatment with Lincomycin and for children, they need to periodically monitor liver and hematological function.

Lincomycin has a neurological -muscle blocker, so it is necessary to be cautious when used with other medications with similar effects (diarrhea drugs such as loopamid, opium to worsen colitis due to slowing toxin secretion).

No intravenous injection when the solution is not diluted.

Use carefully in patients with a history of asthma.

Safety and effectiveness of Lincomycin for children under 1 month of age has not been determined.

Alcohol Benzylic excipients can cause anaphylactic allergic reaction.

Babies:

In the drug with alcohol Benzylic so it should not be used for premature or monthly babies due to the lack of metabolic enzymes and the accumulation risk of alcohol Benzylic, unless it is really necessary because of the high risk of toxicity.

Alcoholic intravenous injection increases adverse reactions that can lead to death in premature babies with an intravenous dosage of alcohol Benzylic in the range of 100 - 200 mg/kg/day.

It inhibits the central nervous system, metabolic acidosis, gas, cardiovascular failure, abnormal hematology ("panting syndrome, yawning").

Persons impaired liver and kidney function:

In the drug with alcohol Benzylic so it should be used in a short time when treating high doses for patients with impaired liver -kidney function because the risk of accumulation and toxicity of metabolic acidosis).

The effect of drugs on drivers and operating machinery

The drug does not affect the driver and operating machinery.

Women during pregnancy and lactation

pregnancy:

Research on experimental animals does not have information about Lincomycin causing birth defects. The drug passes through the placenta and reaches about 25% of the mother serum concentration in the umbilical cord. There has been no complete control of drug use for pregnant people, Lincomycin should only be used for pregnant women when really necessary

Breastfeeding period:

Lincomycin is secreted through breast milk, due to the serious side effects of Lincomycin for breastfed babies, so it is necessary to consider taking medication or breastfeeding. Need to avoid breastfeeding while being treated with Lincomycin.

Drug interaction

Aminoglycosid: Lincomycin does not affect the pharmacokinetics of Gentamicin, but the safety has not been assessed when combining those two drugs.

Kaolin: Dealing drugs containing kaolin reduces Lincomycin absorption. To avoid this, give Lincomycin 2 hours after using Kaolin.

Theophylin: Lincomycin does not interact with theophylin.

Oral contraceptive pills: The effect of oral contraceptives can be inhibited or reduced due to normal bacterial disorders in the intestine, which causes gut -liver blockage.

Neurological - muscle blockers: Be cautious when coordinating with Lincomycin, because Lincomycin has the same property.

erythromycin: Due to the in vitro antagonism between erythromycin and lincomycin, it is not combined with those two drugs.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

To be out of reach of children.

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