Lisanolona injection 80mg/2ml Lisapharma treatment, asthma, allergic rhinitis (5 tubes)

Dosage form Box of 5 tubes x 10ml
Specifications Triamcinolone acetonide

Ingredient

Thành phần cho 2ml

Composition information	Content
Triamcinolone acetonide	80mg

Uses

indications

Lisanolona drugs are indicated in the following cases:

Systemic treatment (injection corticosteroid therapy when corticosteroids can not be applied):

Allergic (control of serious or difficult allergies that traditional measures cannot be resolved), asthma, allergic rhinitis or seasonal rhinitis.

Skin diseases: Dermatitis caused by allergic contact, psoriasis, urticaria, spreading lupus erythematosus.

Rheumatoid arthritis: Progressive polyarthritis.

Lung disease: Bronchitis, asthma, bronchial asthma.

Malignant diseases of blood and leukemia.

On -site treatment:

Injected into joints or around the joints in the treatment of short -term local pain, swelling and stiffness by trauma, rheumatoid arthritis, chronic osteoarthritis, epidemic inflammation, epidemic inflammation and tendonitis.

Inject to wounds to treat keloids.

Pharmacological

corticosteroids are hormones produced by adrenal glands that have many important functions in the body. Triamcinolone is a synthetic glucocorticoide attached to fluor atom. The drug has anti -inflammatory effects, immunosuppressive, anti -allergy. Because the drug is less effective in regulating corticosteroids, it is not used alone to treat adrenal insufficiency.

Corticosteroids reduce inflammation due to cell inflammation, prevent the release of some important chemicals in the immune system, which are related to immune and allergic response, leading to inflammation. Due to reducing the release of this substance in some positions, the drug has the effect of reducing inflammation.

pharmacokinetics

absorption: triamcinolone absorbs well after injection.

Distribution: The drug is distributed into all tissues in the body (muscles, liver, skin, intestines, kidneys ...), through the placenta fence and secretion into small amounts. The drug combines mainly with plasma proteins.

Metabolism: Triamcinolone is metabolized mainly in the liver, partly in the kidney.

Elimination: The drug is eliminated through the urine, half a lifetime range from 2 to 5 hours.

Before taking Lisanolona injection 80mg/2ml Lisapharma treatment, asthma, allergic rhinitis (5 tubes)

How to use

Shake the medicine tube carefully before use. Inject deep into the buttocks.

Dosage

normal starting dose for adults and children over 6 years old:

40 - 120 mg/time, 10 days to 2 weeks of injection.

Then based on the effectiveness of treatment can reduce the dose as low as possible and increase the distance to 2-3 weeks or longer.

Seasonal allergies:

Inject a single dose of 1 - 3 ml (40 - 120 mg). If the dose is needed higher or prolonged the treatment time, it must be closely monitored.

Used on the spot:

Each injection 10 - 80 mg (0.25 - 2 ml)/time, 2 - 3 weeks of injection.

injection in joints:

change the dose depending on the big or small joints.

Adults: 2.5 - 40 mg (0.06 - 1.0 ml)/time.

Children from 6 - 12 years old: 2.5 - 15 mg/time.

Injection in the injury area, in the skin (keloid scars):

Inject from 1 - 3 mg for each location, up to 5 mg (0.125 ml) for each location.

If injected with multiple positions, the total dose does not exceed 30 mg (0.75 ml) for all injection sites. The injection site must be apart over 1 cm.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when using overdose? Symptoms are often related to the digestive tract. Need to report immediately to the doctor in case of an overdose.

What to do when forgetting a dose? If you forget a dose, please contact the doctor immediately for injecting as soon as possible. However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

Common, ADR> 1/100

No report.

Uncommon, 1/1000

No report.

Unknown frequency

Electrolyte: Reducing blood potassium, keeping water causing edema, hypertension, weight gain.

Muscle muscle: Myasthenia, muscle atrophy, muscle fatigue, osteoporosis.

Digestive: gastric ulcer - duodenum, at risk of gastric puncture, pancreatitis.

Endocrine and metabolism: Cushing syndrome, kidney disability, reduced glucose tolerance or severe diabetes, menstrual cycle disorders.

Eye: cataracts, glaucoma.

Skin: Skin atrophy, wounds slow to scars.

Systemic body: Flushing face, body reaction, easy infection. Neurological: Sleep disorders, mental disorders.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Contraindicated

All cases are contraindicated with corticosteroids: Progressive or hidden gastrointestinal ulcers, bacterial infections or uncontrolled fungal infections, some viruses in the progressive stage such as herpes and shingles with manifestations in the eye, hip osteoarthritis (in place).

Progressive virus infection and tuberculosis.

Children under 6 years old.

Pregnant women and suspicion of pregnancy, except in serious illness.

Women who are breastfeeding.

Psychiatric illness, acute viral hepatitis, diabetes dependent insulin.

Intravenous injection, subcutaneous injection, in the tendon, in the spine, heel and infection area.

Caution when used

in prolonged treatment with corticosteroids need to eat a protein -rich diet.

Secondary adrenal hormone reduction caused by drugs can be minimized by reducing the dose slowly. This situation still exists for months after stopping treatment. Therefore, when serious condition occurs, hormone therapy must be reused.

The effect of corticosteroids can increase in patients with thyroid impairment and cirrhosis patients.

neurological disorders can occur when using corticosteroids such as drowsiness, insomnia, perception change, restlessness or mental disorder syndrome. In patients with previous emotions that are unstable or tend to be mental disorders may be worse by corticosteroids.

Be cautious when combined with acetyl salicylic acid for patients with platelets.

Be cautious when indicating corticosteroids in the treatment or support for treatment for patients with epilepsy, impaired renal function, hypertension, diabetes, osteoporosis or weakness.

Monitoring the growth and development of children being treated with prolonged corticosteroids.

Disinfects around the injection site. Must inject the medicine into the buttocks. May have local skin atrophy if subcutaneous.

triamcinolon can react the positive doping test.

Be cautious when indicated for the elderly because this object is often unwanted effects such as osteoporosis, diabetes, high blood pressure, hypokalemia, susceptible to bacterial and thin skin.

The ability to drive and operate machinery

may have mental disorders, drowsiness, insomnia, change awareness, restlessness due to the use of corticosteroids, so be careful when driving and operating machinery.

Pregnancy

does not indicate drugs for pregnant women and suspected pregnancy, except in serious cases. It is necessary to consider the benefits and risks that may occur for both mother and fetus. Closely monitor to detect early if the adrenal disability occurs in newborns.

breastfeeding period

Not only for medication for breastfeeding women.

Drug interaction

Corticosteroids when combined with acetylsalicylic acid may increase the risk of thrombocytopenia. The simultaneous use of triamcinolone acetonide and nonsteroidal anti -inflammatory drugs may increase the risk of stomach ulcers and stomach bleeding.

Liver enzyme induction drugs such as phenobarbital, phenytoin and rifampicin may increase the elimination of triamcinolone acetonide drugs so that it is necessary to increase the dose of triamcinolone to achieve the desired response.

When using Triamcinolone with anticoagulant drugs, the effect of anticoagulants may increase or decrease. Therefore, it is necessary to monitor the coagulation indicators to maintain the anticoagulant effect as expected.

Concomitant use with potassium -causing diuretics such as Thiazide and Furosemide can cause severe potassium loss.

Injectable corticosteroids can reduce the effect of live vaccine.

corticosteroids can increase the unwanted effects of amphotericin B or quinolone.

corticosteroids antagonistic effects of hypoglycemic drugs (including insulin), hypotension and diuretics.

Storage

Store in a cool dry place, room temperature.

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