Lisinopril Stella 10mg tablets treat hypertension, congestive heart failure (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Lisinopril

Ingredient

Composition information	Content
Lisinopril	10mg

Uses

indications

Lisinopril Stella 10 mg is indicated in the following cases:

Treatment of hypertension: Lisinopril is used single or coordinated with other groups of drugs for hypertension (such as diuretics). Heart. Learning

lisinopril is an angiotensin (ACE) enzyme inhibitor (ACE). Ace is a peptidyl dipeptidase peptidyl catalytic reaction that converts angiotensin I into angiotensin II that has vasoconstrictor effect. Angiotensin II also stimulates aldosteron secretion of the adrenal shell. The useful effects of lisinopril on hypertension and heart failure are mainly due to inhibition of the Renin - Angiotensin - Aldosteron system. Ace inhibition reduces angiotensin II in plasma leads to reduced vasoconstrictor activity and reduction of aldosteron secretion.

Dynamic pharmacokinetics

Lisinopril absorbed slowly and incomplete after drinking. The absorption is very different between individuals, about 6 - 60%, an average of about 25% of the dose is absorbed. Lisinopril is an active and non -metabolic diacid. The maximum concentration in plasma is achieved after about 7 hours. Lisinopril is not significantly linked to plasma proteins. The drug is eliminated in the urine in the form of unchanged. The semi -cancellation time after taking multiple doses in patients with normal renal function is 12 hours. Lisinopril is eliminated by hemorrhage.

Before taking Lisinopril Stella 10mg tablets treat hypertension, congestive heart failure (10 blisters x 10 tablets)

How to use

lisinopril stella 10 mg is used by oral.

Dosage

Adults

Hypertension

Patients who are not taking diuretics: Lisinopril's normal starting dose is 5 -10 mg x1 times/day. The dose of the drug should be adjusted according to the patient's blood pressure amplitude response. Lisinopril's usual maintenance dose for adults is 20 - 40 mg/day, using a single dose. In case you cannot stop taking diuretics, sodium salts may be supplemented before starting to take Lisinopril to minimize the risk of hypotension, and the starting dose of lisinopril for adults is 5 mg/day under a minimum of 2 -hour tightening medical supervision until stable blood pressure.

Normal starting dose to treat congestive heart failure in adults with kidney function and normal blood sodium level is 2.5 - 5 mg/day. Effective doses of conventional lisinopril for adults from 5 - 40 mg/day, single dose.

Acute myocardial infarction:

Take a dose of Lisinopril 5 mg within 24 hours after the symptoms of myocardial infarction occur, the dose of 5 mg and 10 mg respectively after 24 and 48 hours, respectively. After that, the maintenance dose should be used for 10 mg/day; Continue to treat Lisinopril for about 6 weeks.

Kidney disease due to diabetes:

The starting dose is 2.5 mg x 1 time/day. The maintenance dose of 10 mg/day for diabetes type 1 has normal blood pressure, up to 20 mg/day if necessary to achieve stable diastolic blood pressure below 75 mmHg. Hypertension in patients with type 2 diabetes, should adjust the dose to achieve stable diastolic blood pressure below 90 mmHg.

Children

Children from 6 to 12 years old:

The starting dose of Lisinopril is 70 mcg/kg (maximum 5 mg) x 1 time/day. The dose is increased in about 1-2 weeks to a maximum of 600 mcg/kg or 40 mg x 1 time/day.

Children over 12 to 18 years old:

Where to start 2.5 mg/day, increased to up to 40 mg/day when necessary.

Patients with renal failure

In patients with adult kidney failure, lisinopril should be reduced depending on the following creatinine (cc) clearance as follows:

cc from 31 - 80 ml/minute: 5 -10 mg x 1 time/day.

cc from 10 - 30 ml/minute: 2.5 - 5 mg x 1 time/day.

Do not use lisinopril for children with glomerular filtration

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Treatment: conventional treatment by transmitting physiological saline solution. It is possible to eliminate lisinopril from the general circulation by hemorrhage.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Lisinopril Stella 10 mg, you may experience unwanted effects (ADR).

Common, 1/100

Systemic: headache

Digestive: Nausea, loss of taste, diarrhea 1/1,000

circuit: Evaluation. The feeling of numbness or as a needle in the lips, hands and feet. ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindications:

Lisinopril Stella 10 mg contraindicated in the following cases:

Patients with a history of edema related to previous treatment with enzyme inhibitors. consciousness.

Caution when using

aortic/myocardial stenosis: like other vasodilators, Lisinopril should be used carefully in patients with the output of the left ventricular heart (such as the case of aortic stenosis, myocardial hypertrophy).

Affects the kidneys: Inhibiting the renin-ankiotensin-aldosteron system that can cause kidney failure and very rare kidney failure and/ or death in sensitive patients (for example, patients with renal function depending on the activity of the renin-angiotensin-aldosterone system as patients with severe blood congestion heart failure). Kidney aortic stenosis, a history of renal failure, and combined with diuretics are also risk factors for kidney failure while treating ACE inhibitors. Prove that kidney failure in patients with acute myocardial infarction (serum creatinine levels exceeding 2 mg/dl), pay attention to stop using lisinopril if the serum creatinine level exceeds 3 mg/dL or double the value before treatment.

Effects on potassium: hyperkalemia can progress, especially in patients with renal impairment or diabetes taking drugs that can increase serum potassium (such as potassium -saving diuretic, potassium supplements, salt -containing salt substitutes). Hyperbonemia can cause serious consequences, risk of death, arrhythmia.

Hypoglycemia : Hypoglycemia can progress in patients using ACE inhibitors with insulin or oral diabetes drugs, especially in the first weeks of coordination treatment or on patients with renal insufficiency.

cough: Astonious and persistent cough has been reported to all ACE inhibitors, recovered after stopping the drug.

Anesthesia surgery: may occur in patients undergoing surgery or during anesthesia with drugs that cause hypotension.

The ability to drive and operate machinery

When driving or operating machinery must pay attention to dizziness and fatigue can sometimes occur.

During pregnancy

During the second and 3rd period of pregnancy, the use of ACE inhibitors can be harmful and even causing fetal deaths. When detecting pregnancy, lisinopril should be stopped as soon as possible.

The period of breastfeeding

It is unclear whether the drug is distributed into human milk or not. Due to the possibility of serious side effects of ACE inhibitors for breastfeeding babies, there is a decision to stop breastfeeding or stop taking Lisinopril, considering the importance of the mother.

Interactive drug

Diuretics: Patients who are taking diuretics and especially beginning diuretics can occasionally excessive blood pressure after the beginning of treatment with Lisinopril.

Non -steroid anti -inflammatory drugs: Concentrated with lisinopril can be more harmful to the kidney function.

Hemorrhage: Lisinopril reduces the impact of potassium loss of thiazid diuretics. The use of Lisinopril along with potassium -saving diuretic (such as Spironolacton, Triamteren or Amilorid), Potassium supplements, or salt -containing salt -containing salt substitutes can lead to significant increase in serum potassium. Therefore, if indicated for combinations of these drugs due to obvious hypokalemia, it should be cautious and regularly monitor serum potassium. Potassium -saving drugs should not be used in patients with heart failure using lisinopril.

Lithi: The toxicity of lithium has been reported in patients using simultaneously lithium with ACE inhibitors with sodium elimination. The toxicity of lithium will be lost when stopping lithium and ACE inhibitors. It is recommended to regularly monitor the lithium concentration in serum if used simultaneously lisinopril with lithium.

Other drugs: Lisinopril simultaneously used with drugs such as nitrate and/or with digoxin does not see evidence of clinical harmful interactions. This includes in patients with myocardial infarction using nitroglycerin intravenously or absorbent paste.

Storage

Store in closed packaging, dry place, avoid moisture. The temperature does not exceed 30 ° C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.