Livorax-4 tablets Microphone analgesic and anti-osteoarthritis (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Lornoxicam

Ingredient

Composition informationContent
Lornoxicam4mg

Uses

indications

livorax medicine is indicated in the following cases:

  • Temporary analgesic in mild to medium acute pain. Like other NSAIDs, Lornoxicam's analgesic and anti -inflammatory effects are associated with Prostaglandin synthesis inhibitors through the activity inhibitors of Cyclo - Oxygenase (COX).

    pharmacokinetics

    lornoxicam are absorbed quickly and completely after drinking. The peak concentration of plasma is 270 µg/l, achieved within 2.5 hours after taking a dose of 4 mg. The pharmacokinetics of Lornoxicam depends on the dose when using the dose from 2 to 6 mg, twice a day. Lornoxicam absorption speed is slowed down and the absorption level decreases (20%) in the presence of food.

    Lornoxicam is found in plasma in non -change form and metabolism of hydroxylation. Hydroxylation does not have pharmacological effects. Lornoxicam's plasma protein mounting ratio is 99% and does not depend on the dose. Lornoxicam is completely metabolized, about 1/3 of the dose is eliminated through the kidney and the remaining 2/3 is excreted through the liver.

    Lornoxicam's pharmacokinetics are the same when used for elderly patients and young patients. Lornoxicam pharmacokinetics parameters are almost unchanged in patients with renal failure. There is no need to adjust the dose for patients with liver failure, except for severe liver failure.

    • Before taking Livorax-4 tablets Microphone analgesic and anti-osteoarthritis (10 blisters x 10 tablets)

    How to use

    use by oral. Should take medicine before meals and drink with plenty of water.

    Dosage

    temporary pain relief treatment

    8 - 16 mg per day, divided into 2-3 times. Total daily dose should not exceed 16 mg.

    Treatment of rheumatoid arthritis and osteoarthritis

    The starting dose of daily recommendations is 12 mg, divided into 2-3 times. The maintenance dose should not exceed 16 mg per day.

    Avoid using Lornoxicam for people with liver/kidney failure if possible. If used, the maximum dose is recommended for people with liver/kidney failure is 8 mg/day.

    There is no recommendation to use Lornoxicam tablets for children under 18 years old.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

    What to do when using overdose?

    What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

    Side Effects

    When using livorax medicine , you may experience unwanted effects (ADR).

    Systemic: headache, dizziness, drowsiness, change of appetite, increased sweating, weight loss, edema, allergies, weakness, weight gain.

    Instructions on how to handle ADR

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Livorax medicine contraindicated in the following cases:

  • Patients with sensitivity to Lornoxicam or any ingredients of the drug.

    • Patients with gastrointestinal hemorrhage , brain vessel hemorrhage, stomach ulcers activity.

    Patients with a history of recurrent stomach ulcers, severe liver failure, severe renal failure.

    Caution when using

    ulcerative and gastrointestinal bleeding

    Need to monitor patient condition after certain periods. Patients with stomach ulcer and/or gastrointestinal hemorrhage while using Lornoxicam should stop taking the drug and need to apply appropriate treatments.

    kidney failure

    Patients with mild renal impairment (serum creatinine clearance rate from 150 - 300 µmol/l) should be tested for precious kidney function, medium renal impairment patients (serum creatinine clearance from 300 - 700 µmol/l) should be tested for kidney function every 1 to 2 months. If the renal function decreases during treatment, it is advisable to stop taking the drug.

    The ability to drive and operate machinery

    Livorax can cause headaches, dizziness, drowsiness, need to be cautious for driving and operating machinery.

    Pregnancy

    should not be used because it has not been fully studied.

    The period of breastfeeding

    should not be used because it has not been fully studied.

    Drug interaction

    lornoxicam interact with the following drugs:

  • Simultaneous use of Lovorax along with anticoagulants or platelets inhibitors can cause prolonged bleeding time. NSAID antagonists of the diuretic effect of Furosemid.

    • Storage

    Store in a cool dry place, avoiding light. Temperature below 30 ° C.

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