Locgoda 0.1% Medboide skin cream for psoriasis, atopic dermatitis (15g)

Dosage form Cream
Specifications Box 1 tube x 15g
Ingredient Mometason Furoat

Ingredient

Thành phần cho 15g

Composition information	Content
Mometason Furoat	0.015g

Uses

Indications

0.1% Locgoda skin cream helps reduce inflammatory manifestations and psoriasis manifestations (except for plaque psoriasis) and atopic dermatitis.

Pharmacological

Mometason Furoat is an external synthetic glucocorticoid, which has local anti -inflammatory activity. Corticosteroids have the effect of inhibiting many types of cells (moisturizing, eosin blood cells, neutrophils, macrophages, lymphocytes) and intermediate substances (histamine, eicosanoids, leukotrien and cytokin) related to inflammation. The leukocytes and macrophages help the start of the intermediaries mentioned above.

Mometason Furoat inhibits the grip of the white blood cells into the damaged vascular wall, then prevented inflammatory cells from moving to the damaged area, causing vascular spasms and reducing the bustle of blood vessels, resulting in inflammatory cells not reaching the site of damaged.

Dynamic pharmacokinetics

absorption: The whole body absorption of Mometason Furoat is 0.7%. Increasing absorption when using icy.

Distribution: Mometason Furoat is associated with protein 98 - 99%.

Metabolism: Mometason Furoat is metabolized in the liver through CYP3A4 and forms metabolites.

Elimination: Mometason Furoat and metabolites are eliminated through feces, bile and urine.

Before taking Locgoda 0.1% Medboide skin cream for psoriasis, atopic dermatitis (15g)

How to use

0.1% Locgoda skin cream used on the spot is applied into thin film and is rubbed into the infected area.

Dosage

recommended dose: Usually apply once a day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using 0.1% Locgoda skin cream is common for unwanted effects (ADR) such as:

Common

Skin: Skin infections, burns, boils, itching, skin atrophy, throbbing pain.

Folliculitis, HPA axis (Children), fungal disease, abnormalities, red acne eggs, loss of skin pigmentation, skin atrophy. ADR:

Notify the physician the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

0.1% Locgoda skin cream in the following cases:

Do not use Mometason Furoat for people with hypersensitivity to drugs or any ingredients of the preparation. Avoid putting cream in the eyes, dermatitis around the eyes.

genital inflammation. Skin atrophy, dermatitis around the eyes, around, chest, infection (such as impetigo, mucous membrane), infected with viruses (such as herpes simplex, herpes zoster and chickenpox, effervescent chicken, virus dermatitis). strain.

Be cautious when using

Mometason banned from applying to the surface, armpits and in groin folds.

The drug is not used for humanity. Avoid putting cream in the eyes.

Mometason is contraindicated to treat diaper dermatitis.

Do not use widespread topics on the body.

Any adverse effect occurs when using the whole miraculous sugar, including adrenal insufficiency, which can appear when using local corticosteroids, especially in children and infants.

Systemic absorption may occur when applying the drug on a large scale, scratched or icy skin. Should be cautious in these cases or when taking the drug for a long time, especially in pediatric patients. Pediatric patients may manifest high sensitivity to the weakening of the lower -pituitary -pituitary -gland and Cushing syndrome than the adult due to the ratio of the skin surface area is larger than the body weight. Should limit the use of Mometason Furoat on the spot for children at the lowest dose while ensuring treatment effect.

Long -term treatment with Mometason Furoat may affect children's growth and development.

Treatment for children over 2 years of age should be under close supervision. Note that young children are more likely to have higher risk of depression of the lower -pituitary - pituitary - adrenal system (because the ratio of skin surface area and weight is related to adults) and the development of atrophy, and Cushing disease.

Do not use for more than 5 days.

Use drugs for women during pregnancy and lactation

Pregnant women

There is no adequate and good test of the use of mometason during pregnancy. Avoid taking large quantities during pregnancy. The adrenal impairment can occur in infants whose mothers use corticosteroids during pregnancy. Closely monitor these young children after birth.

Women who are breastfeeding

Do not know whether the Mometason Furoat is excreted in the milk or not, so it is necessary to use the Memotason Furoat kidney during breastfeeding.

If treated at higher doses or long -term use, stop breastfeeding.

The effect of the drug on the ability to drive and operate machinery

The drug does not affect the driver and operating machinery.

Drug interaction

ISOENZYM CYP3A4 inhibitors: Vimometason Furoat is metabolized mainly in the liver by isoenzyme cytochrom P450 (CYP) 3A4, simultaneous use with drugs is strong inhibitors Isoenzym CYP3A4 (such asketoconazol) can lead to increased plasma concentration Mometason.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

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