Lopradium hard capsules 2mg Imexpharm treat acute diarrhea, rehydration and electrolytes (10 blisters x 10 tablets)

Dosage form Hard capsules
Specifications Box of 10 blisters x 10 tablets
Ingredient Loopramide
Indication Diarrhea
Contraindication Ulcerative colitis, bloating

Ingredient

Composition information	Content
Loopramide	2mg

Uses

indications

Lopradium® drugs are indicated in the following cases:

Loperamid treatment should be accompanied by rehydration and electrolytes.

Treatment of acute and chronic diarrhea symptoms. Loperamid reduces intestinal motility, reduces gastrointestinal secretion and increases anal muscle tone. The drug also has the effect of prolonging the transportation time through the intestine, increasing the transport of fluid and electrolytes through the intestinal mucosa, thus reducing dehydration and electrolyte, reducing the amount of feces. The effect may be related to the reduction of acetylcholin and prostaglandin.

Dynamic pharmacokinetics

about 40% of oral dosage is absorbed through the gastrointestinal tract.

About 97% of drugs associated with plasma proteins.

The drug is metabolized through the liver into an inactive form (over 50%). The half -life of the drug is about 7 - 14 hours. The concentration of drug secretion is very low.

The drug is excreted in feces and urine in constant and metabolic form (30% - 40%).

Before taking Lopradium hard capsules 2mg Imexpharm treat acute diarrhea, rehydration and electrolytes (10 blisters x 10 tablets)

How to use

Lopradium® is oral medication.

Dosage

acute diarrhea

Adults:

Initial dose: 4 mg, then loosen 2 mg loosen each time. Maximum of 5 days.

Usual dose: 6 - 8 mg/day. The maximum dose of 16 mg/day.

Children:

Loperamid is not recommended for children regularly in acute diarrhea.

Children from 6 - 12 years old:

Take 0.08 - 0.24 mg/kg/day divided into 2 or 3 times.

Children from 6 to 8 years old: Take 2 mg, 2 times daily.

Children from 8 to 12 years old: Take 2 mg, 3 times daily.

Maintenance dose: Take 1 mg/10 kg body weight, only drink after one outward.

Chronic diarrhea

Adults:

Initial dose: Take 4 mg, then loosen each time to drink 2 mg until diarrhea.

Maintenance dose: Take 4 - 8 mg/day, divided into small doses (2 times). The maximum dose of 16 mg/day. If the condition does not progress at a dose of 16 mg/day for at least 10 days, should not continue to use the drug.

Children:

Unrespected dosage.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Overdose

Symptoms of respiratory failure and central nervous system, abdominal spasms, constipation, stimulating gastrointestinal tract, nausea, vomiting. Overdose usually occurs when the daily dose is about 60 mg of loopamid.

Handling

Gastrointestinal wash then drink about 100 g of active carbon through the stomach tube. Monitor the signs of central neurological decline, if any, the intravenous injection of 2 mg Naloxon (0.01 mg/kg for children), can be used to repeat the need, the total dose may be up to 10 mg.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Lopradium®, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: constipation, abdominal pain, nausea, vomiting.

Uncommon, 1/1000

Body: fatigue, dizziness, headache.

digestive: abdominal distention, dry mouth.

Rare, ADR

Digestive: intestinal obstruction.

skin: allergies.

Instructions on how to handle ADR

Notice the doctor with unwanted effects encountered when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Lopradium® drug contraindicated in the following cases:

Sensitive to the ingredients of the drug.

When you need to avoid intestinal inhibition.

liver damage.

Heavy colitis, fake colitis.

Syndrome.

Abdominal distention.

Children under 6 years old.

Pregnant women.

Be cautious when using

Caution for patients who reduce liver function or ulcerative colon.

Stop the drug if there is no results within 48 hours.

Track intestinal motility, feces and body temperature.

Monitor abdominal distention.

The ability to drive and operate machinery

Caution for people who are driving and operating machinery when appearing unwanted effects: headache, dizziness.

Pregnancy

There are not enough studies to prove safety in pregnant women, so it should not be used for this object.

The period of breastfeeding

Because loopamid is very small, you can use medication for breastfeeding women but at low doses.

Interactive drug

central nervous system inhibitors, phenothiazine, 3 -round antidepressants, which can cause loperamid's unwanted effects.

Storage

less than 30 ° C, avoid moisture and light.

Other drugs

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