Lorastad 10 tab Stella tablet reduces rhinitis and chronic urticaria (2 blisters x 10 tablets)

Dosage form Tablet
Specifications Box of 2 blisters x 10 tablets
Ingredient Loratadine
Indication Rhinitis, allergic rhinitis, urticaria, itching

Ingredient

Thành phần cho 1 viên

Composition information	Content
Loratadine	10mg

Uses

Indications

Lorastad 10 Tab Stella Pharm is indicated in case of reducing symptoms of allergies including rhinitis and chronic urticaria.

Pharmacokic

Loratadin is a 3 -round antihistamine that has a long -term effect with selective antagonistic activity on the H1 receptor at the periphery.

pharmacokinetics

Loratadin is quickly absorbed through the gastrointestinal tract after drinking, the peak concentration of plasma is reached for about 1 hour.

Increased bioavailability and time to reach the peak plasma concentration slowly when shared with food.

Loratadin is metabolized. The main metabolites are desloratadine with effective antihistamine activity. The average disposal time has been reported to Loratadin and Desloratadin, respectively 8.4 and 28 hours. Loratadine binds about 98% of plasma proteins, desloratadine is less cohesive. Loratadine and its metabolites are detected in breast milk, but it does not pass the brain barrier in significant amounts. Most of the drug dose is excreted in urine and feces in the same amount, mainly in the form of metabolites.

Loratadin's distribution does not see significant changes in patients with severe renal impairment and hemorrhage is not a measure of elimination of loraladin or diameters of desloratadin from the body.

Before taking Lorastad 10 tab Stella tablet reduces rhinitis and chronic urticaria (2 blisters x 10 tablets)

How to use

Lorastad is used by oral.

Dosage

Adults and children over 12 years: 10mg x 1 time/day.

Children from 2 - 12 years old:

Body weight> 30 kg: 10mg x 1 time/day.

Body weight Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms

Adults: Sleep, tachycardia, and headache (use 40 - 180 mg Loratadin). Tré em: Expression of the tower and brush the chest drum (use more than 10 mg).

Treatment

Symptomatic treatment and supportive treatment, start immediately and maintain as long as it is necessary.

In case of acute loratadin overdose, empty stomach should be immediately using ipeca syrup. Taking activated carbon after vomiting can effectively prevent Loratadin's absorption. If vomiting is ineffective or contraindicated (such as with a coma, convulsions), it is possible to conduct a stomach rinse with a 0.8% NaCl solution if there is an internal intubation to prevent the inhalation of substances in the stomach. Saline detergents have the effect of quickly diluting the substances contained in the intestine.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Lorastad, you may experience unwanted effects (ADR).

Heavy ventricular arrhythmia occurred when treated with some H1 histamine anti -receptor drugs; generation 2. That does not appear when treated with loratadine.

When using loratadin at a dose greater than 10 mg daily, the following side effects may occur:

Common, ADR> 1/100

Neurological: headache.

digestive: dry mouth.

Uncommon, 1/1000

Neurological: Dizziness.

Respiratory: dry nose and sneezing.

Other: conjunctivitis.

Rare

Neurology: depression.

Cardiovascular: Heart beat fast, tachycardia on ventricular, brushing chest. digestive: nausea. Metabolism: abnormal liver function, irregular menstruation.

Other: Ban, urticaria, and anaphylaxis.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Lorastad 10 Tab Stella Pharm is contraindicated in the following cases:

Patients with hypersensitivity or allergies to any ingredients of the drug.

Children under 2 years old.

Caution when using

liver failure.

When using Loratadin, there is a risk of dry mouth, especially in the elderly, and increasing the risk of tooth decay. Therefore, it is necessary to clean that the mouth is clean when using loratadin.

The ability to drive and operate machinery

In clinical trials assessing the ability to drive in patients using loratadin, this ability is not impaired. However, patients need to know that there are several rare cases with chickens that can affect the ability to drive or operate machinery.

Pregnancy

Safety to use loratadin while pregnant has not been determined, so only medication if the benefit of treatment is higher than the risk of fetuses

Breastfeeding period

because loraladin is excreted through breast milk and because of the dangers of antihistamines that increase in children, especially newborns and premature babies, should decide to stop breastfeeding or stop taking drugs.

Drug interaction

simultaneous treatment of loratadine and cimetidine leads to increased loratadine concentration in plasma 60%, due to cimetidine metabolic inhibits Loratadine. This has no clinical manifestations.

Simultaneous treatment of loratadine and ketoconazole leads to an increase in loratadine levels in plasma 3 times, due to CYP3A4 inhibition. That has no clinical manifestations because Loratadin has a broad treatment index.

Concomitance of Loratadin and erythromycin leads to increased plasma Loratadin levels. AUC (area under the curve of the concentration over time) of loratadin, an average increase of 40% and the AUC of Descarboethoxyloratadin increases an average of 46% compared to the single Loratadin treatment. On the center of the center, there is no change in the QTC range. Clinically, there is no manifestation of loratadin's safety change, and there is no notice of sedative effects or fainting phenomenon when treating these two drugs simultaneously.

Storage

In closed packaging, dry place. The temperature does not exceed 300C.

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