Lorastad 10mg Stella tablets treat allergic rhinitis, sneezing, runny nose, allergic conjunctivitis (10 blisters x 10 tablets)

Dosage form Tablet
Specifications Box of 10 blisters x 10 tablets
Ingredient Loratadine

Ingredient

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Composition information	Content
Loratadine	10mg

Uses

Indications

Lorastad drugs are indicated in cases where the symptoms of allergies include rhinitis and chronic urticaria.

Pharmacokology

Loratadin is a 3 -round antihistamine that has a long -lasting effect with selective antagonistic activity on H1 receptor.

pharmacokinetics

Loratadin is quickly absorbed through the gastrointestinal tract after drinking, the peak concentration in plasma is about 1 hour.

Increased bioavailability and time to reach peak plasma concentrations slowly when shared with food. Loratadin is metabolized. The main metabolites are desloratadine with effective antihistamine activity.

The average selling time was reported by loratadin and desloratadin, respectively 8.4 and 28 hours. Loratadine binds about 98% of plasma proteins; Desloratadine binds less. Loratadine and its metabolites are detected in breast milk, but it does not pass the brain barrier in significant amounts. Most of the drug dose is excreted in urine and feces in the same amount, mainly in the form of metabolites.

Loratadin's distribution does not see significant changes in patients with severe renal impairment and hemorrhage is not a measure of effectively eliminating loratadine or diameting desloratadin from the body.

Before taking Lorastad 10mg Stella tablets treat allergic rhinitis, sneezing, runny nose, allergic conjunctivitis (10 blisters x 10 tablets)

How to use

Lorastad is used by oral.

Dosage

Adults and children ≥ 12 years: 10mg x 1 time/day.

Children from 2 - 12 years old:

Body weight> 30kg: 10mg x 1 time/day.

Body weight What to do when overdose? Using more drugs will not improve your symptoms; Instead they can cause poisoning or serious side effects. If you suspect that you or anyone else may have overdosed Lorastad, please go to the emergency room at the nearest hospital or hospital. Carry a box, shell, or a pharmacy with you to help doctors have the necessary information.

Symptoms of overdose

Adults: Sleep, tachycardia and headache (dose 40 - 180mg Loratadin).

Children: expression of the tower and brush the chest (use more than 10mg).

Handling

Treatment of ordinary Loratadin overdose includes symptomatic treatment and supportive treatment, starting immediately and maintaining as needed.

In case of acute loratadin overdose, empty stomach should be immediately using ipeca syrup. Taking activated carbon after vomiting can effectively prevent Loratadin's absorption. If vomiting is ineffective or contraindicated (such as with a coma, convulsions), it is possible to conduct a stomach rinse with a 0.9% Naci solution if there is an intravotic tracheal tube to prevent the inhalation of substances in the stomach. Saline detergents have the effect of quickly diluting the substances contained in the intestine.

What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Lorastad, you may experience unwanted effects (ADR). Some side effects recorded in research on users of this drug are:

The severe ventricular arrhythmia occurred when treated with some 2nd generation H1 histamine anti -receptors. That did not appear when treated with loratadine. When using loratadin at a dose greater than 10mg daily, the following side effects may occur: Common

Neurological: headache.

Digestive mouth: dry mouth.

Neurological: Dizziness.

Neurological: depression.

Warnings

Contraindicated

Lorastad drugs contraindicated in the following cases:

Patients with hypersensitivity or allergies to any ingredients of the drug.

Children ≤ 2 years old.

Precautions when taking drugs

Caution when taking Loratadin with liver failure.

When using loratadin is at risk of dry mouth, especially in the elderly, and increasing the risk of tooth decay. Therefore, clean oral hygiene when using loratadin.

The ability to drive and operate machinery

In clinical trials assessing the ability to drive in patients using loratadin, this ability is not impaired. However, patients need to know that there are several rare cases with chickens that can affect the ability to drive or operate machinery.

Pregnancy and lactation

Pregnancy

Safety when using loratadin preparations during pregnancy has not been determined, therefore, only medication if the benefits are higher than the risk of the fetus.

Breastfeeding period

Because loratadin is excreted through breast milk and because of the dangers of antihistamines increasing in children, especially in infants and premature babies, deciding to stop breastfeeding or stop taking the drug.

Drug interaction

simultaneous treatment of loratadine and cimetidine leads to increased loratadine concentration in plasma 60%, due to cimetidine metabolic inhibits Loratadine. This has no clinical manifestations.

Simultaneous treatment of loratadine and ketoconazole leads to an increase in loratadine levels in plasma 3 times, due to CYP3A4 inhibition. This has no clinical manifestations because Loratadin has a broad treatment index.

Concomitance of Loratadin and erythromycin leads to increased plasma Loratadin levels. Loratadin's AUC increased by 40% and the AUC of Descarboethoxyloratadine increased by 46% average compared to only Loratadine treatment. On the center of the center, there is no change in the QTC range. Clinically, there is no manifestation of loratadin's safety changes, and there is no notice of sedative effects or fainting phenomena when treating with this drug.

Storage

You should store at room temperature, avoid moisture and avoid light. No storage in the bathroom or in the freezer.

You should remember that each drug may have different storage methods. Therefore, you should read carefully storage instructions on the packaging or ask the pharmacist.

Keep pills out of reach of children and pets.

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Disclaimer

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