Loratadine 10mg medicine to treat allergic rhinitis, allergic conjunctivitis (10 blisters x 10 tablets)

Dosage form Tablet
Specifications Box of 10 blisters x 10 tablets
Ingredient Loratadine
Indication Allergic rhinitis, allergic conjunctivitis

Ingredient

Composition information	Content
Loratadine	10mg

Uses

indications

Loratadine drugs indicated treatment in cases of allergic rhinitis, allergic conjunctivitis, itching and urticaria related to histamine.

Pharmacological

Loratadin is a 3 -round antihistamine that has a long -lasting antagonistic effect on the peripheral H1 receptor and has no soothing effect on the central nervous system. Loratadin belongs to the second -generation H1 receptor antagonist group (unsafe).

Loratadine has a mild effect on the symptoms of rhinitis and allergic conjunctivitis due to histamine release.

Loratadin also has anti -itching and urticaria effects related to histamines. However, Loratadin has no protection or clinical assistance for severe histamine release such as anaphylaxis.

Antihistamine drugs do not play a role in asthma treatment.

Loratadin has a side effect, especially for the central nervous system, lower than other second -generation antihistamines.

Dynamic pharmacokinetics

Loratadin quickly absorbed after drinking. The average plasma peak concentration of loratadine and its active metabolites (descarboethoxyloratadine) corresponds to 1.5 and 3.7 hours. The half -life of loratadin is 17 hours and of Descarboethoxycloratadin is 19 hours.

Loratadin metabolizes a lot when passing the liver for the first time by the microsom cytochrom P450 enzyme system; Loratadin is mainly converted into Descarboethoxyloratadin, which is a rational effect. About 80% of the total dose of loratadin secreted urine and equal stool, in the form of metabolites, within 10 days.

After taking Loratadin, the antihistamine effect of the drug appears within 1-4 hours, reaching a maximum after 8 - 12 hours and lasts more than 24 hours.

Before taking Loratadine 10mg medicine to treat allergic rhinitis, allergic conjunctivitis (10 blisters x 10 tablets)

How to use

Loratadine tablets for oral tablets. Take the tablet with a glass of water.

Dosage

recommended dose:

Adults, elderly and children aged 12 years and older: 1 tablet/time, 1 time/day. referendum. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when using overdose? In children when taking overdose syrup (exceeding 10mg) shows out of the tower and beating the chest.

Management: Symptomatic treatment and support, start immediately and maintain as long as it is necessary. Loratadin is not eliminated by hemorrhage.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

The severe ventricular arrhythmia occurred when treated with some 2nd generation H1 histamine anti -receptor drugs.

When using Loratadin at a dose greater than 10mg daily, the following effects may occur:

Common: headache, dry mouth, dizziness, dry nose, sneezing, conjunctivitis.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Loratadine drugs contraindicated in the following cases:

Hypersensitivity to any ingredients of the drug.

Caution when using

liver failure.

When using Loratadin, there is a risk of dry mouth, especially in the elderly and increasing the risk of tooth decay. Therefore, clean oral hygiene when using loratadin.

The effect of the drug on the ability to drive and operate machinery

The drug can cause dizziness, so be cautious while driving and operating machinery.

Use drugs for women during pregnancy and lactation

Pregnancy: There is no full research and good tests for Loratadin use during pregnancy. Therefore only use loratadine during pregnancy when necessary, with low doses and in a short time.

Breastfeeding period: Loratadin and metabolites Descarboethoxyloratadin secreted into breast milk. If you need to use loratadin in nursing mothers, use only in low doses and in a short time.

Medicinal interaction

simultaneously used with cimetidine increases loratadine concentration in plasma 60%, due to cimetidine inhibits the metabolic of loratadine. This has no clinical manifestations.

Concentrated with ketoconazole increases the plasma Loratadine levels 3 times due to CYP3A4 inhibition.

This has no clinical manifestations, because Loratadin has a broad treatment index.

Concomitance of Loratadin and erythromycin leads to increased plasma Loratadin levels. AUC (area below the curve of the time of time) of Loratadin increases by 40% and the AUC of Descarbooe - Thoxyratadin increases an average of 46% compared to the solitary Loratadin treatment. On the center of the center, there is no change in the QTC range. Clinically, there is no manifestation of loratadin's safety change, and there is no notice of sedative effects or fainting phenomenon when treating these two drugs simultaneously.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.