Lostad T100 Stella treatment for hypertension, reducing cardiovascular risk (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Losartan Potassium

Ingredient

Composition information	Content
Losartan Potassium	100mg

Uses

indications

Lostad T100 is indicated in the following cases:

Treatment of hypertension. Ho.

pharmacokinetics

No data.

Before taking Lostad T100 Stella treatment for hypertension, reducing cardiovascular risk (3 blisters x 10 tablets)

How to use

Lostad T100 should be swallowed with a glass of water. Can be taken with or not with food, hungry or full. Can be taken with other hypertension medications.

Dosage

Hypertension

Starting and maintaining dose usual: 50 mg x 1 time/day.

Maximum effect of hypertension treatment reaches 3-6 weeks after starting the drug.

Can increase the dose to 100 mg x 1 time/day (taken in the morning).

Losartan can combine with other hypertension drugs, especially with diuretics (such as hydrochlorothiazide).

Reduce the risk of cardiovascular disease and death in adult patients with hypertension with left ventricular hypertrophy

Normal starting dose: 50 mg Losartan x 1 time/day.

can add low -dose hydrochlorothiazide and/or increase the dose of losartan to 100 mg x 1 time/day depending on the response on blood pressure.

Renal protection in adult patients with hypertension and type 2 diabetes, with proteinuria ≥ 0.5 g/day

Normal starting dose: 50 mg Losartan x 1 time/day.

Can increase the dose of Losartan to 100 mg x 1 time/day depending on the response on blood pressure.

Can be used with Losartan and other hypertension drugs (such as diuretics, calcium channel blockers, alpha or beta blockers, and central -acting drugs) as well as the same insulin and other common blood glucose medications (such as sulfonylurea, glitazone and glucosidase inhibitors).

Chronic heart failure

Normal starting dose: 12.5 mg x 1 time/day.

This dose should be adjusted slowly each week (for example, 12.5 mg/day, 25 mg/day, 50 mg/day, 100 mg/day, to the maximum dose of 150 mg x 1 time/day) depending on the patient tolerance.

Special subjects

Patients with intravascular volume decline (such as patients treated with high doses of dosage): The starting dose of 25 mg x 1 time/day should be considered.

Patients with kidney failure and patients with hemolysis: No starting dose.

Patients with liver failure: Lower doses should be used in patients with a history of liver failure. Contraindicated to use Losartan in patients with severe liver failure.

Children:

Do not use Losartan for children under 6 years old, children with liver failure, children with glomerular filtration level

Children from 6 - 18 years old weighing over 20 kg - 50 kg: The recommended dose is 25 mg x 1 time/day. May be up to 50 mg x 1 time/day. Dosage should be adjusted according to blood pressure response.

Weight over 50 kg: Normal dose of 50 mg x 1 time/day. May be up to 100 mg x 1 time/day.

Dosage of over 1.4 mg/kg/day (or exceeding 100 mg) has not been studied in children.

Elderly:

usually does not need to adjust the dose, although it is necessary to consider treatment with the starting dose of 25 mg in patients over 75 years old.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double doses to compensate for missed dose.

Side Effects

When using Lostad T100, you may experience unwanted effects (ADR) such as:

Common

Dizziness;

dizziness; high doses);

Reduce kidney function, renal failure;

Notify the physician the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Lostad T100 is contraindicated in the following cases:

Hypersensitivity to any ingredients of the drug. Patients with hypersensitivity to any ingredients of the drug.

Be cautious when using

need to be very careful when taking the drug for patients in the following cases:

Evaluation: Patients with a history of angioedema (swelling of the face, lips, throat and/or tongue) need to be closely monitored.

Hypotension and electrolyte/epidemic imbalance: Hypotension with symptoms, especially after the first dose and after increasing the dose, can occur in patients with reduced fluid volume and/or sodium loss due to strong diuretic treatment, limiting salt in diet, diarrhea or vomiting. It is necessary to adjust these conditions before using Losartan, or use a lower starting dose. This also applies to children from 6 years old to 18 years old.

Electrolyte imbalance is common in patients with renal impairment, with or without diabetes. Potassium concentration should be closely monitored in plasma as well as creatinine clearance value, especially in patients with heart failure and creatinine clearance from 30 - 50 ml/min.

It is not recommended to simultaneously use potassium -saving diuretic, potassium supplements and salt -containing salt substitutes or other drugs that may increase serum potassium (such as trimethoprim drugs) with Losartan.

Hepatic failure: Dynamic data shows that Losartan concentration in plasma increases significantly in cirrhosis patients, which should be considered lower doses for patients with a history of liver failure. Do not use Losartan in patients with severe liver failure due to lack of treatment experience. It is not recommended to use Losartan in children with liver failure.

Renal failure: As a result of the inhibition of the Renin-Anotensin system, changes in renal function including kidney failure have been reported (especially in patients with renal function depending on the renin-angiotensin-aldosteron system as patients with severe heart failure or renal dysfunction in advance). As with other drugs, it affects the renin-ankiotensin-aldosteron system, increased blood urea and serum creatinine have also been reported in patients with narrowed kidney stenosis on both sides or kidney stenosis in a single kidney; Changes on this kidney function can recover when stopped treatment. Be careful when taking Losartan in patients with kidney stenosis on both sides or kidney stenosis on a single kidney.

It is not recommended to use Losartan in children with glomerular filtration speed

Inexperienced use of losartan for kidney transplant patients.

It is not recommended to use Losartan for patients with primary Aldosteron due to non-response to anti-hypertension drugs that are acting through inhibition of the renin-anidensin system.

As well as other anti -hypertension drugs, excessive hypotension in patients with ischemic heart disease and cerebrovascular disease can lead to myocardial infarction or stroke.

In patients with heart failure, with or without renal failure, as well as other drugs that affect the renin-anidensin system, there is a risk of severe arterial hypotension and kidney failure (usually acute). There is no adequate experience in Losartan treatment in patients with heart failure and at the same time suffering from severe renal failure, patients with severe heart failure (NYHA level IV) as well as in patients with heart failure and arrhythmia with life -threatening symptoms. Therefore, Losartan should be used carefully in these patients. The combination of Losartan with beta blockers should be used carefully.

As with other vasodilators, it is necessary to be particularly cautious in patients with aortic valve stenosis or mitral valve stenosis or obstructive myocardial disease.

Lostad T100 contains lactose. This drug should not be used for patients with rare genetic problems galactose intolerance, total lactase enzyme deficiency or glucose-galactose.

Double blockade of the renin-ankiotensin-aldosteron system (RAAS): There is evidence of simultaneous use of ACE inhibitors, Angiotensin II or Aliskiren receptor blockers increases the risk of hypotension, hyperkalemia and impaired renal function (including acute renal failure). Therefore, it is not recommended to block the double-renotensin-aldosteron (RAAS) system through the use of ACE inhibitors, Angiotensin II or Aliskiren receptor blockers. If dual blockade therapy is considered to be completely necessary, should only be used under the supervision of a specialist and regularly monitor the kidney, electrolyte and blood pressure. Ace ACE inhibitors should not be used simultaneously and Angiotensin II receptor blockers in patients with diabetic kidney disease.

Use for children: Babies have a history of Lostad T100 exposure in the uterus: If the urinary or hypotension occurs, pay directly on the support of blood pressure and kidney perfusion. It may be necessary to transmit blood or fertilize as a measure to reverse the condition of hypotension and/or instead of kidney function is disturbed. On patients, there is a decrease in the volume of circulating, it is necessary to adjust this condition before using Lostad T100.

Used in the elderly:

In clinical studies, there is no difference in effectiveness and safety of Losartan related to age.

The effect of the drug on the ability to drive and operate machinery

When driving or operating machinery must pay attention to dizziness or drowsiness can sometimes occur when treating anti -hypertension, especially when starting treatment or increased dose.

Use drugs for women during pregnancy and lactation

pregnancy:

Do not start using Losartan during pregnancy. When diagnosed with pregnancy, it should be stopped with Losartan immediately and choose the appropriate alternative method.

breastfeeding period:

Losartan is not recommended during breastfeeding, especially when raising newborns or children born in a monthly child.

Drug interaction

drug interactions can affect the activity of the drug or cause side effects.

Patients should notify the doctor or pharmacist a list of the drugs and functional foods you are using. Do not use or increase or decrease the dose of the drug without the guidance of a doctor.

Please see more information about drugs in the instructions for the use of drugs attached.

Storage

Leave a cool place, avoid light, temperatures below 30⁰C.

To be out of reach of children, read the instructions carefully before use.

Other drugs

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