Lowlip 40 microphones treat hypertension from mild to medium (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Telmisartan

Ingredient

Composition information	Content
Telmisartan	40mg

Uses

indications

Lowlip 40 drugs are indicated in the following cases:

Treatment of hypertension from mild to medium. Therefore, the effect of Telmisartan does not depend on the synthesis of angiotensin II.

Dynamic pharmacokinetics

After drinking, Telmisartan's peak (cmax) concentration is achieved after 0.5 - 1 hour. Foods mitigate the bioavailability of Telmisartan, namely reducing the area under the curve (AUC) by about 6% when taking pills 40 mg and about 20% when taking 160 mg. Telmisartan's absolute bioavailability depends on dosage.

When using 40 and 160 mg dose, Telmisartan's bioavailability corresponds to 42% and 58%. The pharmacokinetics of Telmisartan by oral non -linear oral in the dose range from 20 - 160 mg, the rate of concentration increases (CMAX and AUC) is lower than the dose increasing. Telmisartan decomposes according to level 2 function with the last selling time of about 24 hours. The bottom concentration of Telmisartan in plasma when used once a day is about 10-25% of the peak concentration. Telmisartan accumulation coefficient in plasma from 1.5 to 2.0 when using the dose once a day.

Before taking Lowlip 40 microphones treat hypertension from mild to medium (3 blisters x 10 tablets)

How to use

Take oral use.

Dosage

Dosage depends on each patient. The starting telmisartan dose is usually 40 mg, taken once daily. Some patients have effective treatment when taking daily doses of 20 mg. Meeting blood pressure depends on the dose in the dose range of 20 - 80 mg. In most cases, the drug has a clear hypotension within 2 weeks and usually reaches the maximum effect after 4 weeks. If you need to use the dose of 80 mg Telmisartan to obtain a stronger hypotension effect, you can use additional diuretics.

Based on the experience of using Telmisartan for patients with severe renal impairment or patients with hemolysis, it is recommended to use lower doses of 20 mg for these patients.

Patients with mild hepatic failure should not be taken in excess of 40 mg daily.

Use for children: Telmisartan's safety and effectiveness in children has not been set up.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when overdose? If symptomic hypotension occurs, supportive treatment must be treated. Can not remove telmisartan by cup.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Lowlip 40, you may experience unwanted effects (ADR).

Telmisartan is often well tolerated. The side effects are usually light and transient; Rarely have to stop using the drug. The most common side effects are back pain, diarrhea, sore throat, headache, dizziness, pain, fatigue and nausea.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using Lowlip 40, you need to read the instructions carefully and refer to the information below.

contraindicated

Lowlip 40 contraindicated drug in the following cases:

Contraindicated in patients with hypersensitivity to any ingredients of the drug.

Be cautious when using

can use long last telmisartan, as long as the speed of creatinin> 30 ml/min.

Patients with loss of epidemic in the heart should be treated to overcome this situation, or should start using Telmisartan under close supervision. Patients with biliary obstruction disorders or liver disorders should also start treatment under close supervision. Patients with jurors may have a vertical posture hypotension, need to closely monitor the blood pressure of these patients.

The ability to drive and operate machinery

Because the drug can cause headaches, dizziness should not drive and operate machinery after taking the drug.

Pregnancy

Medicines directly acting on the Renin - Angiotensin system may cause disease or death for the fetus and babies when used for pregnant women. There have been reports on less amniotic fluid, maybe due to the reduced renal function of the fetus. When detecting pregnancy, it is necessary to stop using Telmisartan as soon as possible.

The period of breastfeeding

It is unknown whether Telmisartan is excreted in milk or not. Because the drug can be harmful to breastfeeding, it is necessary to decide to stop breastfeeding or stop the drug, taking into account the importance of the drug for the mother.

Drug interaction

Not enough data to evaluate safety and effectiveness when using Telmisartan simultaneously with ACE inhibitors or beta - adrenergic blockers. Telmisartan may increase the effect of reducing blood pressure of this drug.

Digoxin: Concentrated with Telmisartan increases the concentration of Digoxin in serum, so it is necessary to monitor the concentration of Digoxin in the blood at the beginning of treatment, adjusting and stopping Telmisartan to avoid the possibility of digoxin overdose.

Diuretics: Increases the hypotension effect of Telmisartan.

Warfarin: Concentrated with Telmisartan for 10 days reduces the concentration of warfarin in the blood but does not change the INR.

Potassium diuretics: Supplied potassium mode or use of other drugs that cause hyperactical potassium can increase the effect of hyperkalemia of Telmisartan.

Storage

Store in a cool dry place, avoiding light. Temperature below 300C.

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