Lucass 200 Maxim medicine for pneumonia, bronchitis, sore throat (2 blisters x 10 tablets)
Dosage form Box of 2 blisters x 10 tablets
Specifications Cefpodoxim
Ingredient
| Composition information | Content |
| Cefpodoxim | 200mg |
Uses
indications
Lucass 200 drugs are indicated in the following cases:
On In vitro and clinical, Cefpodoxim Proxetil usually works on the following bacteria:
Gram negative: Escherichia Coli, Proteus Mirabilis, Klebsiella, Moraxella (Branhamella) Catrhalis, Neisseria Gonorrhoeae, Haemophilus Influenzae.
Dynamic pharmacokinetics
After drinking, Cefpodoxim Proxetil is absorbed through the digestive tract and is metabolized by non -specific esters into Cefpodoxim metabolites that work.
Birth of Cefpodoxim Proxetil is about 50%, this bioavailability increases when used with food. Half of the serum is 2.1 - 2.8 hours for people with normal kidney function. Half of the serum increases to 3.5 - 9.8 hours in people with kidney disabled.
After taking a dose of Cefpodoxim Proxetil, in healthy adults with normal kidney function, plasma concentration is achieved within 2-3 hours and an average value of 1.4 mcg/ml, 2.3 mc/ml and 3.9 mcg/ml for doses of 200 mg, 200 mg and 400 mg, respectively. About 40% Cefpodoxim binds to plasma proteins.
The drug is eliminated in the form of non -changing glomerular filtration and the excretion of the renal tubules. About 29 - 38% of the dose is eliminated within 12 hours in adults with normal kidney function. The drug is eliminated to a certain extent when the hemorrhage.
Before taking Lucass 200 Maxim medicine for pneumonia, bronchitis, sore throat (2 blisters x 10 tablets)
How to use
Take oral use.
Dosage
Adults
Sore throat and/or tonsillitis: 100 mg x 2 times/day (use the form of preparation in accordance with the dose) for 5-10 days.
Having pneumonia in the acute community: 200 mg x 2 times/day for 14 days.
Exacerbats of chronic bronchitis: 200 mg x 2 times/day for 10 days.
Inhabited gonorrhea: The only dose of 200 mg, followed by oral doxycyclin treatment to prevent Chlamydia infection.
Skin infection and skin structure: 400 mg x 2 times/day for 7-14 days.
Uncomplicated urinary tract infections: 100 mg x 2 times/day (use the form of preparation in accordance with the dose) for 7 days.
Children under 13 years old
Acute otitis media: 5 mg/kg (maximum 200 mg) x 2 times/day for 10 days.
Sore throat and/or tonsillitis: 5 mg/kg (maximum 200 mg) x 2 times/day for 5-10 days.
Dosage for people with kidney failure: The dose must be reduced depending on the degree of renal failure. For patients with creatinine clearance smaller than 30 ml/min and no blood separation, common dose.
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do
do when overdose? However, in cases of overdose, hemolysis or peritoneal fertilizer can help remove Cefpodoxim from the body. What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not use double the prescribed dose.
Side Effects
When using Lucass 200, you may experience unwanted effects such as:
When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
contraindicated
Lucass 200 drugs contraindicated in the following cases:
Be cautious when using
Before starting treatment with cefpodoxim Proxetil, a thorough survey of patients' allergies with cephalosporin, penicillin or other drugs. It is necessary to be cautious when using Cefpodoxim Proxetil for patients with a history of allergies to beta - lactam because of the cross -sectional reaction occurs.
If allergies with Cefpodoxim Proxetil occur, the medication should be discontinued and properly treated.
Be cautious when using Cefpodoxim Proxetil for patients with severe renal impairment and patients with a history of gastrointestinal diseases, especially colitis.
Using Cefpodoxim Proxetil for a long time can cause excessive sensitive strains to grow, need to monitor patients carefully. If superinfection occurs during treatment, it is necessary to take appropriate treatment.
The ability to drive and operate machinery
does not affect.
Pregnancy
There are no adequate and controlled studies in pregnant women. Because animal reproductive research does not always predict the response on humans, it is only used for pregnant women when necessary.
Breastfeeding period
cefpodoxim excreted into breast milk. Because of the ability to endure breastfeeding, they must stop breastfeeding when taking the drug, or taking into account the importance of the medication for the mother.
Interactive drug
antacids:
Concentrated with high -dose antacids (such as sodium bicarbonate and hydroxid aluminum) or H2 blockers reduces the plasma concentration of plasma from 24 - 42% respectively and reduces absorption from 27 - 32%.
Probenecid:
As with other beta lactam antibiotics, the excretion of the kidney of Cefpodoxim is inhibited by probenecid and thus increases about 30% of the area under the AUC curve and increases the peak concentration of plasma to 20%.
Poisoning drugs:
Although the ability to poison the kidneys has not been seen in Cefpodoxim Proxetil when used alone, it must also closely monitor the kidney function when patients use Cefpodoxim Proxetil along with other toxic drugs for kidney toxicity.
Storage
Store in a cool dry place at a temperature of less than 30 ° C, avoiding light.
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