Magisix Agimexpharm tablets treat magnesium diseases (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Magnesium lactate, vitamin B6

Ingredient

Composition information	Content
Magnesium Lactate	470mg
Vitamin B6	5mg

Uses

Indications

Magisix 470mg drug is indicated in the following cases:

The drug is used to treat severe, separate or combined magnesium deficiency.

Magnesi is a cation in the intracellular, Magnesi reduces the stimulation of nerve cells, reduces muscle conductivity and participates in many enzyme reactions. As an element of the body, half the amount of magnesium is concentrated in the bone.

Magnesi Lactat is used orally as an additional source of Mg2+ in the treatment of Magnesi deficiency.

Clinically, quantitative results in plasma:

From 12 to 17mg/l: Magnesi shortage.

under 12mg/l: Severe Magnesi shortage.

The lack of magnesium may be original due to congenital abnormalities in the metabolism of magnesium or secondary due to reduction of supply (severe malnutrition, alcoholism, feeding only by injection), due to poor absorption of gastrointestinal tract (chronic diarrhea, holes in the gastrointestinal tract, parathyroid insufficiency), due to loss of kidney (kidney disease, chronic chronic, increase in chronic pool, increase chronic pool, increase chronic pool, increase primary Aldosterone, cisplatin treatment).

Some non -specialized clinical manifestations may appear due to lack of magnesium such as: Run, muscle weakness, muscle spasms, ventricular, increased reflexes, mental disorders (irritability, insomnia ...), heart rhythm disorders (extra -minded tachycardia), digestive disorders (diarrhea).

Related to pyridoxin (vitamin B6)

pyridoxin is a coenzym, involved in many metabolic processes and helps Magnesi penetrate easily into the cell. Vitamin B6 exists in 3 forms: pyridoxal, pyridoxin and pyridoxamin, when entering the body, it is transformed into pyridoxal phosphate and partly into pyridoxamin phosphate. These two substances act as coenzymes in the metabolism of protein, glucid and lipid. Pyridoxin participates in the synthesis of gamma acid - Aminobutyric (GABA) in the central nervous system and participates in Hemoglobin synthesis.

pharmacokinetics

Related to Magnesi

Magnesi is a factor of the body, the average concentration of 17mmol/kg of the body of which 99% is in the cell, selectively absorbed on the small intestinal mucosa. Here, Magnesi is absorbed from 40 to 50% of the amount.

Nearly 2/3 of magnesi in cells is distributed into bone tissue and the remaining one -thirds are distributed in smooth or muscular muscles as well as in erythrocytes.

Magnesi is transformed into magnesium chloride. About 15 - 30% of the Magnesi Chloride has just produced and then eliminated through urine in people with normal kidney function.

Magnesi is eliminated through urinary roads. In the kidneys, 70% of Magnesi in plasma is filtered in the glomeruli, 95 - 97% of this mg2+ is reabsorbed in the renal tubules. The amount of magnesium is eliminated in the urine accounts for about 1/3 of the amount. Magnesi passed the placenta and a small amount of magnesium found in breast milk.

Related to pyridoxin (vitamin B6)

pyridoxin is quickly absorbed through the gastrointestinal tract, except for malabsorption syndrome. After drinking, the drug is mostly reserved in the liver and part of the muscle and brain.

pyridoxin excreted mainly through the kidneys in the form of metabolism. The amount of introduction, if exceeding the daily needs, most excreted in the form of unchanged.

Before taking Magisix Agimexpharm tablets treat magnesium diseases (10 blisters x 10 tablets)

How to use

Take oral use. Should divide the dose every day into 2 or 3 times: morning, noon and afternoon. Drink with plenty of water.

Dosage

Adults

Lack of Magnesi weighs: 6 tablets/day.

Tibetans: 4 capsules/day.

Children over 6 years old

Use 2 - 4 capsules/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Overdose

Normally, taking Magisix overdose does not cause toxic reaction due to magnesium in case of normal kidney function. However, Magnesi poisoning may occur in the case of renal failure.

The harmful effects depend on the concentration of magnesium in the blood and the signs are: lower blood pressure, nausea, vomiting, depression of the central nervous system, decreased reflexes, ECG abnormalities, respiratory, coma, cardiac arrest and respiratory paralysis.

Handling

If the manifestation of overdose, stop taking the drug.

Treatment

Water compensation, diuretic. In the case of kidney failure, dialysis or peritoneal divergence is necessary.

What to do when forgetting a dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Magisix, you may experience unwanted effects (ADR).

Vitamin B6

Heavy allergic reactions: rash, urticaria, itching, shortness of breath, chest tightness, swelling of the mouth, face, lips, or tongue, reducing tactile, fever, tremor, loss of air conditioning, numbness or mouth, numbness or tingling in the skin.

High doses of vitamin B6 for a long time can increase severe peripheral neuropathy.

Magnesi

If allergy symptoms such as rash, shortness of breath, swelling of the face, tongue, lips or throat, need to go to the nearest medical facility for timely medical care.Common

diarrhea, flatulence, abdominal or digestive disorders.

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

sensitive to one of the ingredients of the drug.

Severe renal failure with creatinine clearance below 30ml/min.

Be cautious when using

Do not use Magisix with any other drug containing magnesi or vitamin B6.

When there is a lack of calcium, in most cases, it is necessary to compensate for magnesium before compensating for calcium.

Be cautious when taking medication in case of medium renal failure to avoid the risk of increased blood in the blood. It is necessary to have a doctor's supervision when taking the drug.

Magisix is only used for objects over 6 years old.

Magisix contains lactose. Patients with rare genetic problems are galactose tolerance, lactose deficiency or malposure Glucose Galactose should not use this drug.

Overdose can cause laxative.

The ability to drive and operate machinery

There is no information on the effects of drugs on driving and operating machinery.

Pregnancy

only use drugs in pregnant women when really necessary.

Breastfeeding period

Drug interaction

Avoid using magisix combined with preparations containing phosphate and calcium salts are inhibitors of magnesium absorption process at the small intestine.

In case of treatment in combination with oral tetracyclin, two drugs must be taken at least 3 hours away.

Do not coordinate with Levodopa because Levodopa has inhibited vitamin B6.

quinidine: Increasing plasma quinidine and overdose risk.

Dosage of pyridoxin 200mg/day may cause a decrease in 40-50% of the concentration of phenytoin and phenobarbital in the blood in some patients.

To avoid interactions between drugs, notify the doctor or pharmacist the drugs being used.

Storage

Cool dry storage, avoid light, temperature below 30⁰C.

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