Magne - B6 Stella Treatment of heavy blood magmesium (5 blisters x 10 tablets)

Dosage form Box of 5 blisters x 10 tablets
Specifications Magnesium lactate, pyridoxine hydrochloride

Ingredient

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Composition information	Content
Magnesium Lactate	470mg
Pyridoxine hydrochloride	5mg

Uses

indications

Magne-B6 drug indicated in the following cases:

Magnesium heavy blood, separate or accompanied by other mineral deficiencies. When there is a calcium deficiency, it is recommended to supplement magnesium before adding calcium. Kreb, enamel adenyl cylase creates camp and reactions of different phosphatase enzymes in protein synthesis and nucleic acid.

Magnesi is also necessary for the transmission and neuromuscular activity, the mineralization of the bone and the function of the parathyroid hormone.

Vitamin B, exists in 3 forms: pyridoxal, pyridoxin and pyridoxamin, when entering the body transforms into pyridoxal phosphate and partially into pyridoxamin phosphate. These two substances act as coenzymes in the metabolism of protein, glucid and lipid. Pyridoxin participates in the synthesis of gamma acid - Aminobutyric (GABA) in the central nervous system and participates in hinh hopoglobulin.

Dynamic pharmacokinetics

After drinking, about 1/3 of magnesi is absorbed from the small intestine and even the Magnesi salts are generally absorbed very slowly. The ratio of Magnesi is absorbed increased by decreasing the amount of magnesi use. About 25 - 30% Magnesi binds to protein in plasma. Magnesi salt used orally eliminated through the urine (the amount is absorbed) and the feces (the amount is not absorbed). A small amount is distributed into breast milk. Magnesi passed the placenta.

pyridoxin, pyridoxal and pyridoxamin are absorbed in the stomach, intestines after drinking and transformed into pyridoxal phosphate and pyridoxamin phosphate activity. They are stored mainly in the liver where oxidation forms 4-pyridoxic acid and other non-active substances, which are eliminated in urine. When increasing the dose, the larger amount of the drug is excreted intact through the urine. Pyridoxal passes the placenta and is distributed in breast milk.

Before taking Magne - B6 Stella Treatment of heavy blood magmesium (5 blisters x 10 tablets)

How to use

Magne-B6 medicine is taken 2-3 times in the morning, noon and evening. Should take medicine with meals due to drugs can cause diarrhea.

Dosage

Dosage to treat heavy blood magnesium:

Adults: 6 tablets/day.

Children: 2 - 6 capsules/day depending on age

Adults: 4 capsules/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Overdose:

Symptoms (rare in patients with normal kidney function). Introduction, slow heart (slow heartbeat), central neurological inhibition (intense sleep), coma, hypotension (dizziness or dizziness), loss of muscle sensation, kidney failure (unknown seeing or double seeing, hyperuria or decrease in urinary), respiratory failure (hard worship).

Treatment:

Stop using preparations containing magnesi.

Specific treatment: If the serum magnesium concentration exceeds 5 MEQ/l and patients with symptoms, slow venous infusion 10 ml of 10% calcium gluconate in minutes. Can repeat this dose once.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Magne-B6 drugs often experience unwanted effects (ADR) such as:

Increasing blood magnesium is less common after taking magnesium salt unless there is kidney failure.

Notify the physician the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Magne-B6 drug contraindicated in the following cases:

Hypersensitivity to any ingredients of the drug.

Be cautious when using

oral magnesium salt is used carefully for patients with renal impairment (which can lead to high magnesium concentration, need to reduce the dose of magnesium supplements).

The effect of the drug on driving and operating machinery

The drug does not affect the ability to drive and operate machinery.

Use drugs for women during pregnancy and lactation

Pregnant women

Magnesi and Pyridoxal through the placenta. When used for pregnant women, should monitor fetal heart rate and avoid use within 2 hours before birth.

breastfeeding women

Magnesi and Pyridoxin are excreted into breast milk. Consider using Magnesi and Pyridoxin to suit breastfeeding.

Drug interaction

interactive of magnesi:

Cellulose sodium phosphate or Edetat Dinatri: simultaneously use with Magnesi supplements, resulting in Magnesi's link; Therefore, patients should not take Magnesi supplements within 1 hour when taking cellulose sodium phosphate or Edetat Dinatri.

Oral preparations containing calcium: Concentrated with Magnesi supplements can increase the concentration of calcium or serum magnesium in sensitive patients, mainly in patients with renal insufficiency.

Oral tetracyclin medications: simultaneously used with Magnesi supplements can reduce the absorption of tetracyclin drugs. Due to the ability to create non -absorbing complexes; Patients should not use Magnesi supplements within 1-3 hours when taking Tetracyclin.

Interaction of pyridoxin:

levodopa: pyridoxin reduces the effect of levodopa, but this does not happen if used with dopa decarboxylase inhibitors.

altretamine: pyridoxin reduces the effect of altretamine.

Phenobarbital and Phenytoin: Pyridoxin reduces the concentration of phenobarbital and phenytoin in serum.

hydralazin, isoniazid, penicillamin and oral contraceptive pills may increase the need for pyridoxin.

Storage

Leave a cool place, avoid light, temperatures below 30⁰C.

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