Magnesi B6 Vidipha tablets treat cases of heavy magnesium (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Magnesi lactate dihydrate, pyridoxin HCl

Ingredient

Thành phần cho 1 viên

Composition information	Content
Magnesi lactate dihydrate	470mg
Pyridoxin HCl	5mg

Uses

indications

Magnesi - B6 drugs are indicated in the following cases:

Treatment of severe, separate or combined magnesium deficiency. When there is a lack of calcium, it is accompanied by the majority of cases to compensate for Magnesi before compensating for calcium.

Vitamin B6 exists in 3 forms: pyridoxal, pyridoxin and pyridoxamin, when entering the body transformed into pyridoxal phosphate and partially into pyridoxamin phosphate. These two substances act as coenzymes in the metabolism of protein, glucid and lipid. Pyridoxin participates in the synthesis of gamma acid - Aminobutyric (GABA) in the central nervous system and participates in Hemoglobulin synthesis.

Daily needs for children are 0.3 - 2mg, adults about 1.6 - 2mg and pregnant or lactating mothers are 2.1 - 2.2mg. It is rare for vitamin B6 deficiency in humans, but it may occur in the case of absorption disorders, congenital metabolic disorders or drug disorders caused by drugs. For patients treated with isoniazid or women who take birth control pills, vitamin B6 needs more daily than usual.

Many drugs such as pyridoxin antagonists: isoniazid, cycloserin, penicilamine, hydralazin and other carbonyl groups can be combined with vitamin B6 and inhibit the Coenzyme function of this vitamin. Pyridoxin is used to treat seizures and/or coma due to isoniazid poisoning. These symptoms are considered to be caused by reduction in gaba concentrations in the central nervous system, perhaps due to the inhibiting the activity of pyridoxal - 5 - phosphate in the brain.

pyridoxin is also used as a medicine to support other measures in the treatment of acute poisoning caused by Giromitra fungus to treat nervous effects (such as convulsions, coma) of methylhydrazin, hydrolyzed from gyrometrin toxin in these mushrooms.

magnesi lactate dihydrate:

Magnesi is a positive ion found in intracellular. Magnesi reduces neuron stimulation and muscle neuron transmission. Magnesi participates in many enamel reactions.

Magnesi Lactat Dihydrate is used orally as an additional source of Mg2+ in the treatment of Magnesi deficiency.

pharmacokinetics

vitamin B6:

absorption: Pyridoxin is quickly absorbed through the gastrointestinal tract, except for cases of malabsorption syndrome.

Distribution: After drinking, the drug is mostly reserved in the liver and part of the muscle and brain.

Elimination: pyridoxin excreted mainly through the kidneys in the form of metabolism. The amount of introduction, if exceeding the daily demand, most excreted in the form of unchanged.

magnesi lactate dihydrate:

absorption: Magnesi absorbs slowly and incomplete through the digestive tract, even the types of salts. Only about 1/3 of Magnesi is absorbed through the small intestine after drinking.

Distribution: About 25-30% Magnesi attached to plasma proteins.

Elimination: Magnesi oral orally excreted in urine (for the absorbed part) and in the feces (for the absorption part). A small amount of magnesium is found in breast milk. Magnesi passed the placenta.

Before taking Magnesi B6 Vidipha tablets treat cases of heavy magnesium (10 blisters x 10 tablets)

How to use

Dose dosage daily into 2 or 3 times: morning, noon, afternoon: Each time should drink with plenty of water.

Dosage

Average: Adults

Lack of Magnesi weighs: 6 tablets/24 hours.

Scratcher: 4 tablets/24 hours.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when overdose?

Management: If an overdose occurs, mainly treat symptoms and support.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Magnesi - B6, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: diarrhea, abdominal pain.

Neurological: high doses of pyridoxin (200mg/day) long (over 2 months) can cause severe peripheral neuropathy, progressive from the body of unstable and numbness to the numbness and clumsy hands. This condition can recover when stopping the drug, although there is still more or less sequelae.

Rare, 1/10000

Digestive: Nausea, vomiting.

Instructions on how to handle ADR

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Magnesi - B6 Contraindicated in the following cases:

Severe renal failure with the clearance of creatinine below 30ml/min.

Too hypersensitivity to any ingredients of the drug.

Be cautious when used

may have a vitamin B6 dependence syndrome if taking a long -term drug in high doses.

The ability to drive and operate machinery

The drug does not affect the ability to drive and operate machinery.

Pregnancy

only use magnesi in pregnant women when really necessary.

The period of breastfeeding

because Magnesi is excreted through breast milk, does not use Magnesi for breastfeeding women.

Drug interaction

Avoid using magnesium in combination with preparations containing phosphate and calcium salts are inhibitors of magnesium absorption in the small intestine.

In case of treatment in combination with oral tetracyclin, two drugs must be taken at least 3 hours apart.

pyridoxin reduces the effect of levodopa in the treatment of Parkinson's disease.

High doses of 200mg/day pyridoxin can cause 40-50% decrease in the concentration of phenytoin and phenobarbital in the blood in some patients.

pyridoxin can lighten depression in women who take birth control pills.

Oral contraceptives can increase the demand for pyridoxin.

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding light.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.