Magnesi Sulfate Kabi 15% treatment solution for torsion, prophylaxis and jerky treatment (10 tubes)

Dosage form Box of 1 blister x 10 tubes
Specifications Magnesi Sulfat

Ingredient

Thành phần cho 10ml

Composition information	Content
Magnesi Sulfat	1.5g

Uses

Indications

Magnesi Sulfate is indicated in the following cases:

Treatment of peak cardiac arrest (TDP).

Pharmacokological

Magnesi is a major cation in extracellular fluid and is also an essential electrolyte for the body. It is an important factor involved in the operation of many enzymes, related to neurotransmitters and participate in muscle stimulation.

The drug also has the effect of inhibiting the central nervous system and can cause vasodilation.

Increasing the amount of magnesium in the blood can lead to the following changes: extending the QT, PR, QRS.

pharmacokinetics

When intravenously, the drug is absorbed quickly and has immediate effect, and the long -lasting effect for 30 minutes.

About 25-30 % of the drug is linked to plasma proteins.

The drug is excreted mainly through the kidneys. In patients with renal failure, it can cause Magnesi accumulation.

The drug is given the placenta and excreting into breast milk.

Before taking Magnesi Sulfate Kabi 15% treatment solution for torsion, prophylaxis and jerky treatment (10 tubes)

How to use

slow intravenous injection.

intravenously, diluted in glucose solution or salt water.

Dosage

Treatment of peak cardiac arrest (TDP)

Intravenous injection of 8 mmol cation Magnesi intravenously means slow intravenous injection 2 g Magnesi sulfate, then continuous intravenous infusion from 0.012 to 0.08 mmol cation magnesi/minute means from 3 to 20 mg/minute Magnesi sulfate.

Provincial -level potassium treatment is related to hypoglycemia

intravenously from 24 to 32 mmol cation Magnesi means 6 to 8 g Magnesi sulfat24. The addition of potassium must be done by a transmission different from Magnesi.

Stop treatment when Magnesi concentration is normal.

Magnesi supplements in the process of re -balancing electrolytes and in venous feed

intravenously 6 - 8 mmol cation Magnesi for 24 hours, ie 1.5 g to 2 g Magnesi sulfate.

In children, the usual dose is 0.1 to 0.3 mmol/kg cation Magnesi, ie 25 - 75 mg/kg Magnesi sulfate for 24 hours.

Products and treatment for eclampsia

To prevent jerking or treatment when this reaction appears, 16 mmol cation magnesi intravenous infusion means 4 g Magnesi sulfate for 20 to 30 minutes.

In the case of the shock still continues, an additional 16 mmol cation Magnesi is 4.9 magnesi sulfate without exceeding the maximum accumulation of 32 mmol cation Magnesi, which is 8 g Magnesi sulfate during the first treatment time.

Then, continuously transmitted from 8 to 12 mmol cation Magnesi, which means the word equivalent to 2 - 3G Magnesi Sulfate Heptahydrate every hour, in the next 24 hours.

Only use the drug when a doctor's application.

Patients with renal failure: The appropriate dose is required.

What to do when overdose?

Magnesi sulfate plasma concentrations began to overdose of 4MEQ/l, deep tendon reflexes, decreased and can be absent at nearly 10MEQ/l. At 12 to 15meq/l, respiratory paralysis can be a potential danger.

Can fight respiratory effects by intravenously intravenous with calcium salts.

Before starting each injection dose, the respiratory frequency should be at least once a minute and the kidney function should be fully tested. In case of overdose, ventilation support must be conducted until calcium intravenous injection.

Peritonics or dialysis can be required if the Magnesi Sulfate overdose is severe. Overdose Magnesi Sulfate causes central nervous inhibition.

What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Magnesi Sulfate, you may experience unwanted effects (ADR). Some side effects recorded in research on users of this drug are:

The main adverse reaction is mainly related to high plasma magnesium levels including flushing, sweating, hypotension , circulatory failure, heart inhibition and central nervous system. Respiratory inhibitors are mostly life -threatening effects.

Notice immediately to the doctor or pharmacist when encountering the side effects of the drug.

Instructions on how to handle ADR

Mild mild magnesium increased treatment often limits the absorption of magnesium. Furosemid. If you encounter any unwanted effect, stop taking the medication and immediately notify your doctor or immediately go to the nearest medical facility for timely treatment.

Warnings

Contraindicated

Contraindications in the following cases:

Hypersensitivity to Magnesi Sulfate or any ingredient of the drug.

Liver brain disease, liver failure or kidney failure.

Should avoid Magnesi Sulfate in patients with cardiac blocks.

Precautions when using

need to be cautious when using Magnesi salt for patients impaired renal function . Need to reduce the appropriate dose.

Be careful when injecting Magnesi for people with myasthenia gravis, preventing the seriousness of this condition or my muscle weakness. Need to assess risk benefits in each patient before starting treatment. Magnesi sulfate should not be used for liver coma if
is at risk of kidney failure.

Need to monitor serum concentration regularly in patients using magnesium sulfate.

The ability to drive and operate machinery

There is no information because no research has been found about the effect of drugs on driving and operating machinery.

Pregnancy and lactation

Safety of using drugs for pregnant women has not been established, however, in an emergency when patients with eclampsia can be life -threatening of both mother and baby, Magnesi Sulfate can be used to reduce this situation.

It is not recommended to use Mignesi Sulfate during pregnancy or period for children to compensate when it is really necessary and must be supervised by health workers.

Magnesi passes through the placenta. When used in pregnant women, the heart rate should be monitored and should be avoided within 2 hours of birth.

Other special subjects (elderly, children, allergies)

No report.

Drug interaction

What drug can Magnesi Sulfate interact with?

Medicine interactions can change the ability of the drug or increase the effects of side effects.

It is best to write a list of drugs you are taking (including prescription, non -prescription and functional foods) and for a doctor or pharmacist. Do not arbitrarily take the drug, stop or change the dosage of the drug without the permission of the doctor, especially:

Magnesi sulfate injection affects the competition and nerve reduction inhibition.

Does the food and alcohol interact with Magnesi Sulfat?

Please consult your doctor about taking medicine with food, alcohol and tobacco.

What health status affects Magnesi Sulfate?

Your health status may affect the use of this drug. Tell your doctor if you have any health problems.

Storage

You should store at room temperature, avoid moisture and avoid light. No storage in the bathroom or in the freezer.

You should remember that each drug may have different storage methods. Therefore, you should read carefully storage instructions on the packaging or ask the pharmacist.

Keep pills out of reach of children and pets.

Expiry date: 24 months from the date of manufacture.

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