Materazzi 50mg davipharm tablets relax skeletal muscle, treat spasms, muscle spasms (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Eperisone

Ingredient

Composition information	Content
Eperisone	50mg

Uses

Indications

Materazzi is indicated in the following cases:

Treatment of spasms and muscle spasticity. It can also have vasodilators.

Inhibiting experimental muscle spasms: Eperison hydrochloride inhibits gamma spasms and alpha spasms in cats and mice, depending on the dose.

Inhibition of the marrow reflex: Eperison hydrochloride inhibits single and synags, created by stimulating the centrifugal nerve roots in the cat.

Reduce the sensitivity of the opportunity through gamma motor neurons: Eperison hydrochloride inhibits the activity of the center -oriented nerve (IA) from the occasion of the person after taking the drug for 20 minutes. Eperison hydrochloride inhibits gamma motor neurons, but does not directly affect the muscles of animals. Therefore, Eparison hydrochloride reduces the sensitivity of the opportunity through gamma motor neurons.

Impact vasodilation and increased blood flow

Eperison hydrochloride relaxes blood vessels thanks to the effect of Ca ++ antagonistic effects on blood vessel muscles and sympathetic neurological inhibition effects.

Eperison hydrochloride increases blood flow in the skin, muscle, external artery, internal artery and vertebra artery.

Analgesic effects and inhibition of pain in the spinal cord

When Eparison Hydrochorid enters the spinal cord in the mouse, the pain of the mouse's tail will be inhibited and this reflex will return when the Eparison Hydrochorid is not available.

Create easy movement in arbitrary movement

When used to treat hard paralysis in patients with cerebral blood, Eparison Hydrochorid improves the Momen Cybex curve and mechanical electromechanical, easy to make arbitrary movements such as stretching and folding limbs without reducing muscle power.

Dynamic pharmacokinetics

Eperison hydrochloride has been used by oral at 8 healthy adults with a single dose of 150 mg/day, for 14 consecutive days and plasma drug concentration is determined on 88 and 14.

The time reaches the maximum concentration (TMAX) in the range of 1.6 to 1.9 hours, the maximum concentration (cmax) is 7.5 to 7.9 ng/ mL. The half -life (T1/ 2) is 1.6 to 1.8 hours and the area under the plasma concentration curve (AUC) is 19.7 to 21.1 ng. Eparison hydrochloride plasma concentrations are measured on the 8th and 14th day without a significant change compared to the first day.

Before taking Materazzi 50mg davipharm tablets relax skeletal muscle, treat spasms, muscle spasms (10 blisters x 10 tablets)

How to use

Materazzi medicine is taken orally.

Dosage

The usual dose for adults: take 3 capsules/day, divided into 3 times after each meal. Dosage should be adjusted according to the age and symptoms of the patient.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

There is no report.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Materazzi medicine you may experience unwanted effects (ADR).

Other undesirable effects:

Common, ADR> 1/100

No report.

Clinically important unwanted effects:

shock and anaphylactic reaction: In case of symptoms such as itching, urticaria, face edema or other parts, shortness of breath ... should stop the drug and apply appropriate treatment.

Stevens-Johnson syndrome, Lyell syndrome: Should stop the drug and take appropriate therapeutic measures in the event of symptoms such as fever, rash, blister, itching, eye congestion, stomatitis ...

Liver - Kidney: liver and kidney dysfunction.

Neurology: Neurological symptoms such as drowsiness, insomnia, headache, spasticity, tremor.

Other: dry mouth or symptoms of urinary disorders.

Instructions on how to handle ADR

Notify the physician the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Materazzi drugs contraindicated in the following cases:

Patients with a history of drug sensitivity.

Patients with liver dysfunction.

Be cautious when using

weak, dizziness, drowsiness or other symptoms may occur when taking the drug. Stop using or reducing the dose when signs of those symptoms. Patients who use drugs should not drive or control machines.

Elderly patients often reduce physiological function, thus reducing dose and careful supervision for these patients.

To be out of reach of children.

The ability to drive and operate machinery

There is no report.

Pregnancy

Materazzi's safety in pregnant women is not well known. The drug should only be used for pregnant patients or suspected pregnancy if the expected treatment results are higher than the risk may occur.

Breastfeeding period

Materazzi is reported that excreted in breast milk. Materazzi is recommended to avoid use in breastfeeding women. If necessary, patients should stop breastfeeding.

Used for children: The safety of drugs when used for children has not been set, lack of clinical research.

Drug interactions

have reported that after simultaneous use of methocarbamol with Tolperizon Hydrochloride (a compound with a structure similar to Perizon Hydrochorid), there is an eye regulation disorder.

Storage

In a dry place, avoid light, the temperature does not exceed 30 ° C.

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