Maxgel SPM skin cream treats dermatitis, scratches, rash, skin fungus (10g)

Dosage form Tube x 10g
Specifications Gentamycin, Clothimazole, betamethason

Ingredient

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Composition information	Content
Gentamycin	0.1%
Clothimazole	1%
Betamethason	0.05%

Uses

Indications

Maxgel drug is indicated in the following cases:

Dermatitis responds to corticosteroids when there is secondary infection complication. Eczema , dermatitis, inflammation, rash, skin fungus. Skin.

betamethason is a synthetic corticosteroid that works in the treatment of some skin diseases because of the anti -inflammatory effect, itching effect.

Gentamycin is an antibiotic of the aminoglycosides that kill bactericidal effects through inhibiting bacterial protein biosynthesis. Gentamycin has a wide antibacterial spectrum, which works on most common bacteria in skin infections.

Clotrimazol is an synthetic derivative of imidazol with a chemical structure similar to miconazole, which has a broad -spectrum antibiotic effect, the drug has the ability to inhibit most types of micro -fungi in humans, including yeast and malassezia furfur.

The mechanism of acting of clotrimazol is to link with phospholipids in the fungal cell membrane, changing the permeability of the membrane, causing loss of intracellular essential substances leading to the destruction of mushroom cells.

pharmacokinetic

betamethason

After applying the drug, especially under the iron or when the skin is torn, Betamethasone can be absorbed in sufficient amounts to cause the whole body effect. Betamethason quickly distributed into all tissues in the body.

The drug can be placed in the placenta and can be distributed into breast milk in small amounts.

In the circulatory system, Betamethason is strongly connected to plasma proteins, mainly with globulin and albumin is less. Betamethasone is less widely linked to protein than hydrocortisone (cortisol).

The half of their lifetime also tends to be longer. Betamethasone is metabolized mainly in the liver but also metabolizes in other tissues and excreted into the urine.

Metabolism of synthetic corticosteroids, including better betamethasone and their protein bonding pressure is lower, which can be explained stronger than natural corticosteroids.

gentamycin

Gentamycin Sulfate: The absorption into the circulating system of Gentamycin has been reported after using skin topicals on peeled and burned skin.

Clotrimazol

Used on the skin, clotrimazol is less absorbed. Six hours after applying the cream and solution of 1% Clotrimazol radioactive on the skin intact and on the acute inflammatory skin, Clotrimazol concentration varies from 100ng/cm in the horny layer to 0.5 - 11g/cm3 in the thorn layer and 0.1 kg/cm2 in the subcutaneous tissue layer.

The amount of maxgel drugs absorbed is metabolized in the liver and then excreted through feces and urine.

Before taking Maxgel SPM skin cream treats dermatitis, scratches, rash, skin fungus (10g)

How to use

Wash the infected skin area with warm saline, dry and apply a thin layer of medicine, apply maxgel dermatitis cream from outside to inside.

Dosage

Apply 2-3 times a day, apply until the condition is improved. Then continue to apply once a day.

In case of psoriasis, skin patches in the elbows, knees thicken, after applying the drug for the first time, it is necessary to cover the topical skin, the effectiveness of treatment will increase many times. The next application does not need to be closed.

What to do when overdose? Using more drugs will not improve your symptoms; Instead they can cause poisoning or serious side effects.

If you suspect that you or anyone else may have overdosed Maxgel, please go to the emergency room at the closest hospital or nursing hospital.

Bring boxes, shells, or pharmacies with you to help doctors have the necessary information.

Do not give your medicine to others even though you know they have the same disease or look like they may have the same disease. This can lead to overdose.

Please consult your doctor or pharmacist or product package for more information.

What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Maxgel , you may experience unwanted effects (ADR). Some side effects recorded in research on users of this drug are:

Like other corticosteroids, when applied on a large scale and prolonged the drug can cause skin atrophy (manifestation of skin cracks, thin skin, surface blood vessels).

The drug can be absorbed through the skin, causing adrenal enhancement, especially when applied to the thin skin and for children.

If you encounter any unwanted effect, stop taking the medication and immediately notify your doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Contraindications in the following cases:

Not for patients with hypersensitivity to any ingredients of the drug.

People with acne (both red acne and regular acne).

Dermatitis around the mouth, infection of pluralistic virus (single herpes, chickenpox).

Do not use pregnant women in the first 3 months, breastfeeding, children under 1 year of age.

Do not use inflammation or external ear fungus when the patient has perforation of the eardrum.

Precautions when taking the drug

When applying the drug on the facial area should be cautious, not to put the cord in the eyes. The facial skin is more likely to shrink than other areas and the scars left dark.

When the infection is too wide, it is not advisable to apply the drug because there is a risk of overdose due to the drug absorbed through the skin, which must be treated with systemic antibiotics.

When applying the drug for more than 7 days without showing signs of improvement, the medication must be taken and select other drugs in combination with the treatment of the whole body, because Clotrimazol obscures the signs of infection.

The ability to drive and operate machinery

does not affect the alertness of the driver and operating machinery.

Pregnancy and lactation

Pregnancy

Due to the unsafe safety of pregnant women, it is only used when the treatment benefits are higher than the risk. Before taking the drug, you should consult your doctor, pharmacist.

Breastfeeding period

It is still not known whether the drug will go to breast milk or not. During breastfeeding should be cautious to use the drug. If necessary, please consult your doctor to consider the benefit of the mother and the risk of the child.

Other special subjects (elderly, children, allergies)

Do not use for children under 1 year of age.

Drug interaction

Interacting with betamethason

Because the drug contains betamethasone, it is possible to interact with paracetamol, three -round antidepressants, oral diabetes or insulin, glycosides digitalis, phenobarbital, phenytoin, rifampicin or ephedrin, anticoagulants of Coupharin.

Interaction with Gentamycin

Concomitance use of gentamycin with kidney toxic drugs including other aminoglycosides, vancomycin and some cephalosporin medications, or with relatively toxic drugs for hearing organs such as ethacrynic acid and maybe Furosemid will increase the risk of toxicity.

This risk also increases when using gentamycin simultaneously with drugs that inhibit neurotransmitter.

Indomethacin may increase plasma concentrations of aminoglycosides if used.

The use of anti -vomiting drugs such as Dimenhydrinat can cover the first symptoms of vestibular poisoning.

Interaction with clotrimazol

The antagonistic effect between imidazols (including clotrimazol) and antibiotic polyene in vitro has been reported.

Perhaps due to the iMidazol inhibits the synthesis of ergosterol while polyene antibiotics have anti -fungal effects by attaching sterols of the cell membrane. The impact of clotrimazol on liver mitochondrial enzymes is not problematic for topical forms.

Storage

You should store maxgel drugs at room temperature, avoid moisture and avoid light. No storage in the bathroom or in the freezer.

You should remember that each drug may have different storage methods. Therefore, you should read carefully storage instructions on the packaging or ask the pharmacist.

Keep pills out of reach of children and pets.

Expiry date: 24 months from the date of manufacture.

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