Maxitrol Alcon eye drops for eye inflammation (5ml)

Dosage form Bottle x 5ml
Specifications Dexamethasone, Polymyxin B Sulfate, Neomycin Sulfate

Ingredient

Composition information	Content
Dexamethasone	5mg
Polymyxin b sulfate	30000iu
Neomycin sulfat	17500iu

Uses

indications

Maxitrol alcon 5ml drug is indicated in the following cases: Eye inflammation when considering the need for antibacterial drugs.

Pharmacokology

maxitrol alcon 5 ml is a special pharmacy combined with anti -inflammatory properties of dexamethasone with bactericidal antibiotic effects of neomycin and polymyxin b.

Corticosteroids reduce inflammation to many different types of agents and they delay or slow down the process of healing wounds. Because corticoids can inhibit the body's resistance mechanism against infection, in special cases, when the immunosuppressive effect has a significant significant meaning, it is necessary to use corticosteroids with antibiotics.

dexamethasone is among the most effective corticosteroids. Thanks to the anti -inflammatory effect and the ability to absorb large, so when combined with antibiotics will be easy to treat inflammatory processes with bacterial infections.

Neomycin and polymyxin b sulphat in the maxitrol alcon 5 ml special will be effective against the most common pathogenic microorganisms with eye staph, E.coli, Haemophilus Influenzae, Klebsiella/Enterobacter Species, Neisseria Species and Blue Pus bacteria.

Maxitrol Alcon 5 ml does not fully protect against Serratia Marcescens and streptococcus including pneumococcal.

Neomycin Sulfate is a broad spectrum antibacterial antibiotic, anti -Gram -positive and gram -negative effect and is at low risk with bacterial resistance.

However, most stretches and green pus infections are resistant to Neomycin. Polymyxin B Sulfate is a selective antibacterial drug against Gram -negative microorganisms. Polymyxin B is one of the most effective antibiotics against blue pus.

Studies have shown Neomycin Sulfate in combination with polymyxin B Sulfate to form a synergistic effect when considering anti -vitro active activity against many types of microorganisms, including yellow staphylococcus and blue pus bacillus as well as Baciilus subtilis, E.coli, St.falis, Proteus Vulgaris and St.agalactiae. Many tests have confirmed the above results. Therefore, Maxitrol Alcon 5 ml has a double effect: An antibacterial and anti -inflammatory drug.

Dynamic pharmacokinetics

neomycin and polymyxin B can be absorbed after use at the eye when some tissues are damaged. The corticosteroids are absorbed through aquatic, cornea, iris, darkness, eyelashes and retina.

System absorption occurs only in very special cases when taking high doses or for prolonged treatment. The whole body absorption of dexamethasone is very small when used outside the eye. Dexamethasone is eliminated by metabolic line: about 60% of the dose detected in urine format 6 - beta - hydroxy dexamethasone. Dexamethasone form is constant, not found in urine. Selling time in plasma is very short, from 3-4 hours. Dexamethasone has albumin bonding, on average 77 - 84%. The clearance of 0.111 - 0.225 l/h/kg and the integral distributed from 0.576 - 1.15 l/kg. The bioavailability of dexamethasone when taking oral dose is about 70%.

Neomycin is poorly absorbed through the gastrointestinal tract, about 97% of oral dose is excreted in the form of unchanged in feces. After taking 3 g, the serum peak concentration reaches about 4 mcg/ml and when the drug is absorbing the same. The absorption of the drug may increase when the mucosa is inflamed or damaged. When absorbed, the drug will quickly eliminate through the kidneys in the form of activity. The semi -exhaust cycle of the drug is about 2-3 hours.

Polymyxin B is well absorbed through the peritoneal, not absorbed through the gastrointestinal tract, except for young children with up to 10% of the dose, not significantly absorbed through the mucosa and skin intact or peeling the outer coating as in the case of severe damage. Polymyxin B Sulphate is widely distributed in the body tissue, does not see the distribution in the cerebrospinal fluid (even when the meninges are inflamed) and does not pass the placenta.

Polymyxin B does not bind much with plasma. The semi -exhaust cycle of adults with normal kidney function is 4.3 - 6 hours. About 60% of the absorption drug is eliminated in the form of unchanged urine through glomerular filtration. The drug continues to excrete in 24 - 72 hours after the last dose. Dialysis or peritoneal filtration does not exclude polymyxin b.

Before taking Maxitrol Alcon eye drops for eye inflammation (5ml)

How to use

Maxitrol alcon 5 ml is only used for eye drops.

Shake thoroughly before use.

Dosage

use drugs in adolescents, adults, including the elderly

Small, small cases of 1 to 2 drops of medication in the conjunctiva bag of the eye is sick, 4-6 times daily. Decreasing gradually compared to small drugs when clinical tides are improved, do not stop treating too early.

Severe cases, small 1-2 drops per hour, then gradually decrease and stop treatment when the inflammation is gone.

Patients need to gently close the eyelids and block the nasal tissue after finishing the eye to reduce the amount of drugs absorbing in the general circulation, reducing the whole body side effects.

Use in children

Safety and effectiveness of drugs in children has not been determined.

Used in patients with liver failure, renal failure

Maxitrol Alcon 5 ml eye drops have not been studied on these objects. However, because the active ingredients in the preparation are very little absorbed in the common circulation after small eyes, it is not necessary to adjust the dose.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Case of small eyes overdose, should wash your eyes with warm water.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using maxitrol alcon 5 ml , you may experience unwanted effects (ADR).

There have been side effects when using steroid and antibacterial combination drugs, which may be due to steroid components, antibacterial components or mixed. There are no exact figures on the frequency of side effects because there is no statistics on the total number of patients treated.

The most common reactions due to antibacterial components are allergic reactions. The reactions due to the steroid component according to the frequency of decreasing as follows: Increased internal pressure (IOP) is likely to progress to glaucoma , and irregular visual nerve damage, forming cataracts under the back of the back, and slowly wound.

Secondary infection: secondary infections occurred after using combined drugs containing steroids and antibiotics. Fungal infections in the cornea especially occur after long -term steroids. Once steroid treatment must be considered for the possibility of fungal infections in any case with prolonged corneal ulcer. Secondary infections can also occur due to decrease in the body's response.

Instructions on how to handle ADR

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Maxitrol alcon 5 ml drug in the following cases:

Cortex epithelium caused by Herpes Simplex (tree keratitis), beef bean disease, chickenpox and many other diseases of the virus conjunctival and cornea. Mycobacterium infection in the eyes, fungal disease caused in the parts of the eye.

Patients with hypersensitivity to any ingredients of the drug.

After surgery to remove unpleasant corneal objects.

Cases of untreated pus infections.

Be cautious when using

recommendations

Prolonged medication can lead to glaucoma, with optic nerve damage, vision and market defects, and form cataract under the back. Using long -term drugs can reduce the response of the body and thus increases the risk of secondary infections in the eye. In cases of thinning the cornea, there have been cases of eyeballs occurring when using local steroids.

In acute pus diseases in the eye, steroids can cover signs of infection or worsen the existing infection. If using these drugs for 10 days or longer, it is advisable to monitor internal pressure in a regular way, although this is difficult to do in children and patients who do not cooperate.

It is recommended not to use contact lenses during the treatment of eye infections. Therefore, the patient is advised not to wear contact lenses while using this preparation. In addition, it should be noted that the preparation contains Benzalkonium Chloride preservatives, which can color soft contact lenses.

Caution

First prescription and repeat treatment of more than 20 ml (4 vials) need to be performed by a specialist physician after checking the patient thoroughly with amplifiers such as microscopic lights and when suitable for fluorescent dyeing. When experiencing serious or hypersensitivity reactions, it is necessary to stop immediately.

After using long -term steroids, it is necessary to see the possibility of prolonged corneal fungus.

Information for patients: Do not touch the tip of the eye drops into anything because it can contaminate the drug. Do not use the drug when carrying contact lenses.

The ability to drive and operate machinery

is the same as when the eye is small, temporarily blurred and visual disorders can affect the ability to drive and control the patient's machines. If you are blurred after the medication, the patient must wait until it is clear to drive or control machines.

Pregnancy

There is no recommendation to the use of maxitrol alcon 5 ml eye chaos for pregnant women.

breastfeeding period

Many drugs can be eliminated through milk and harms breastfeeding. The decision to stop breastfeeding or not using small eye mixes should be considered based on the benefits of the drug for the mother and the risk of children.

Drug interaction

No special research has been done with Maxitrol Alcon 5 ml using eye small eyes. The interaction between each component has been recorded when using the whole body. However, the absorption of dexamethasone, neomycin sulphate and polymyxin B sulphate in the spot is very small, so the risk of drug interaction is very low.

If you use more than 1 eye drops, the drug should be spaced at least 15 minutes apart.

Storage

Keep the vial vertically. Storage at the heat of 8 - 30 ° C, not to freeze.

Leave the medicine out of the reach of children

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.