Meclon Doppel Pharma vaginal placement treat cervicitis, vagina (2 blisters x 5 tablets)

Dosage form Box of 2 blisters x 5 tablets
Specifications Clotrimazole, Metronidazole

Ingredient

Composition information	Content
Clotrimazole	100mg
Metronidazole	500mg

Uses

Indication

Meclon has a treatment effect:

cervicitis , cervicitis - vagina, vaginitis and vulva - vaginal inflammation caused by trichomonas vaginalis along with candidiasis or bacteria.

Pharmacological

Meclon is a combination of Metronidazol and Clotrimazol.

Metronidazol is a derivative of nitroimidazol with antibacterial and animal antibacterial spectrum. It has the effect of killing Trichomonas directly and has the effect of Gram -positive anaerobic bacteria, spore bacilli, Gram -negative anaerobic bacteria. Meclon especially works on Gardnerella Vaginalis. It has no effect on the vaginal acid -preferred flora.

Clotrimazol is an imidazol conductor with wide antifungal spectrum (Candida ...). It also works for Trichomonas Vaginalis, Gram -positive bacteria, Toxoplasma ...

The combination of Clotrimazol and Metronidazol has been shown to enhance the effects of the drug, causing the drug to achieve the following three main treatment effects:

There is a wide antibacterial spectrum due to the combination of 2 active ingredients.

Enhancing antifungal effects, animal antigens and antibacterial.

Reduce or lose drug resistance.

Pharmacokinetics

absorption

Rabbits, dogs and mice tests show that Clotrimazol and Metronidazol are not absorbed into the bloodstream when used to repeat Meclon along the skin. When using the vagina, Metronidazol and Clotrimazol are absorbed about 10% to 20%.

Before taking Meclon Doppel Pharma vaginal placement treat cervicitis, vagina (2 blisters x 5 tablets)

How to use

Put 1 Meclon in the vagina daily when lying on your back, the legs slightly folded.

Dosage

Put 1 tablet daily.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Meclon you may experience some unwanted effects (ADR).

Common, ADR> 1/100

Skin: itching, allergic contact dermatitis, skin rash.

Uncommon, 1/1000

No report.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Melon drug contraindicated in the following cases:

Patients with hypersensitivity to any ingredients of the drug.

Caution when using

should not be used simultaneously with Meclon with Metronidazol by oral.

The ability to drive and operate machinery

The drug does not affect the ability to drive and operate machinery.

Pregnancy

only use drugs during pregnancy when really necessary and must be monitored carefully.

Breastfeeding period

No report.

Drug interaction

Although when the vagina is placed, Metronidazol and Clotrimazole are less absorbed by the whole body, but still need to be cautious when using this drug with other drugs because Metronidazol increases anticoagulant oral effects, especially Warfarin. Metronidazole has a disulfiram -style effect, so it is not used simultaneously these two drugs to avoid nervous effects such as psychosis, confusion.

Use Metronidazol for patients with high blood lithium concentrations (because they are using lithium) will increase the serum lithium concentration.

metronidazole increases the effect of vecuronium is a non -reducing muscle relaxant.

Tacrolimus concentration in the serum of people with liver transplant increases when used simultaneously with clotrimazol, thus reducing Tacrolimus dose as demand.

Clotrimazol may reduce the effectiveness of some antibiotics.

Storage

Temperature does not exceed 30 ° C.

Other drugs

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