Mediclovir 3% MediPharco eye ointment for corneal inflammation (5g)

Dosage form Tube x 5g
Specifications Acyclovir

Ingredient

Composition information	Content
Acyclovir	3%

Uses

Indications

Mediclovir drugs are indicated in the following cases: Treatment of HERPES SIMPY virus keratitis.

Pharmacokological

aciclovir is a substance similar to nucleosid (acycloguanosin), selected effect on the herpes virus cell.

To have the effect of aciclovir must be phosphoryi turned into activated form as Aoiclovir Triphosphate. At the beginning, aciclovir is converted into aciclovir monophosphate thanks to the enzyme of the virus, thymidinkinase, then transformed into aciclovir diphosphate and triphosphate by some other cell enzymes. Aciclovir Triphosphate inhibits the synthesis of the virus DNA and the multiplication of the virus without affecting the metabolism of normal cells.

The most powerful Aciclovir on Herpes Simplex Typ 1 virus (HSV - 1) and worse in Herpes Simplex Typ 2 virus (HSV -2), Varicella Zoster virus (VZV), the weakest effect on Cytomegalovirus (CMV).

Heavy keratitis caused by herpes, this case may be used with 3% aciclovir eye drops for local treatment.

pharmacokinetic

aciclovir is used in the form of eye ointment quickly absorbed through corneal epithelium and eye tank tissue for toxic concentrations for the virus achieved in aquaculture.

Food does not affect the absorption of the drug. Aciclovir is widely distributed in body fluids and organs such as brain, kidneys, lungs, intestines, liver, spleen, muscle, uterus, mucosa and vaginal fluid, tears, aquatic fluid, semen, cerebrospinal fluid. Links to low protein (9 - 33%). Half a lifetime of the drug in adults is about 3 hours, in children from 2-3 hours, in newborns 4 hours. A small amount of drugs are metabolized in the liver, while the majority (30-90% of the dose) is eliminated through the kidney in the form of unchanged.

Before taking Mediclovir 3% MediPharco eye ointment for corneal inflammation (5g)

How to use

Investigate a small amount of ointment in the bag with the same conjunctiva.

Dosage

Investigate a small amount of ointment in the bag and conjunctiva 5 times daily. Should continue at least 3 days after the dose of treatment

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Mediclovir, you may experience unwanted effects (ADR).

A few patients feel slightly throbbing as soon as they look into the eye. Dotted keratitis, eyelid inflammation, conjunctivitis. However, there is no need to stop the drug, will not leave sequelae.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Mediclovir drugs are contraindicated in the following cases: Hypersensitivity to the composition of the drug.

Precautions when using

Caution with kidney failure.

The ability to drive and operate machinery

Caution should be cautious because the drug can cause eye blur when used.

Pregnancy

should only use aciclovir for pregnant women when the benefits are more likely to occur with pregnancy. Hence only when there is a doctor's instructions.

Breastfeeding period

The drug is excreted by breast milk when used orally. Should be cautious when taking the drug for breastfeeding.

Medicinal interaction

Simultaneous use of zidovudin and aciclovir can cause a state of sleep and drowsiness.

amphotericin B and ketoconazole increase the anti -virus effect of aciclovir.

Storage

In a dry place, temperatures below 30 ° C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.