Medlon 4 DHG Pharma anti -inflammatory, immunosuppressant in arthritis, lupus erythematosus (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Methylprednisolone

Ingredient

Composition information	Content
Methylprednisolone	4mg

Uses

indications

Medlon 4 drugs are indicated in the following cases:

Anti -inflammatory and immunodeficiency in: rheumatoid arthritis, erythema lupus, vasculitis, bronchial asthma, chronic ulcerative ulcer, hemolytic anemia, granulocytosis, severe allergies including anaphylaxis.

The drug is also indicated in the treatment of nephrotic syndrome. Due to methylation Prednisolon, corticosteroid effect on salt metabolism has been excluded, so there is little risk of salt, water and edema. The anti -inflammatory effect of methylprednisolon increases by 20% compared to the effect of Prednisolon, 4mg of methylprednisolon, which is valid as 20mg of hydrocortison.

pharmacokinetics

bioavailability is about 80%, plasma concentration reaches a maximum of 1-2 hours after taking the drug. The sale time is about 3 hours. Methylprednisolon is metabolized through the liver, the metabolites are excreted through the urine.

Before taking Medlon 4 DHG Pharma anti -inflammatory, immunosuppressant in arthritis, lupus erythematosus (10 blisters x 10 tablets)

How to use

oral medication.

Take the tablet with a glass of water.

Dosage

Determine the dose for individuals. The necessary dose to maintain the desired treatment is lower than the dose needed to achieve the initial effect, and must determine the lowest dose that can be achieved by the need for gradually reducing the dose step by step until the signs or symptoms increase.

When you need to use big doses for a long time, apply medication therapy the day after control of the process of the disease, there will be less unwanted effects because of the recovery time between each dose.

In a daily -way therapy, using a single dose of methylprednisolon every 2 days, in the morning in the span of natural secretion glucocorticoid.

Acute asthma attacks: Use 32 - 48mg (8 - 12 capsules)/day for 5 days.

rheumatoid arthritis: Use 4 - 6mg/day. Executive period 16 - 32mg (4 - 8 capsules)/day.

Chronic colic ulcer: Use 8 - 24mg (2 - 6 tablets)/day.

Immune hemolytic anemia: Use 64mg/day, at least 6-8 weeks.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose? It is necessary to consider suspending or stopping the drug.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when forgetting a dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using the drug, you may experience unwanted effects (ADR).

The most common effects occur most when using methylprednisolon is high and long -term. Methylprednisolon inhibits prostaglandin synthesis and thus losing the effect of prostaglandin on the gastrointestinal tract, including inhibiting gastric acid secretion and protecting the stomach lining.

Common

Insomnia, nerves are easily agitated;

Increase appetite, indigestion;

Dizziness, convulsions, mental disorders, fake tumors in the brain, headache, mood change, delirium, hallucinations, refreshment;

edema, hypertension; Sodium and water, hyperglycemia;

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Medlon 4 drugs against in the following cases:

Hypersensitivity to prednisolon.

Precautions when using

Use cautiously in people with osteoporosis, new blood vessel connection, mental disorders, stomach ulcers, duodenal ulcers, diabetes, hypertension, heart failure and growing children.

Due to the risk of unwanted effects, caution must be used with all body corticosteroids for the elderly, with the lowest doses and in the shortest possible time.

Acute adrenal insufficiency may occur when the drug is stopped suddenly after a long time of treatment or when there is stress. When using high doses, it may affect the effects of vaccinations.

Effects of the drug on the job: Precautions when using the drug because the drug can cause unwanted effects affecting people working on high and other cases.

The ability to drive and operate machinery

Caution when using Medlon 4 because the drug can cause unwanted effects that affect the ability to drive, operate machinery.

Pregnancy and lactation

Pregnancy

For extension of body corticosteroids for mothers can lead to mitigation of the baby's weight. Using corticosteroids in pregnant women should consider benefits that can be achieved compared to the risks that may occur with mother and child.

Breastfeeding period

Not contraindicated corticosteroids for nursing mothers.

Drug interaction

methylprednisolon is a cytochrom P450 enzyme induction and is the substrate of the P450 3A enzyme, so this drug affects the metabolism of ciclosporin, erythromycin, phenobarbital, phenytoin, carbamonepin, ketoconon, ketoconon, ketoconon Rifampicin.

Phenytoin, Phenobarbital, Rifampin and diuretics decreased potassium can reduce the effectiveness of methylprednisolon.

methylprednisolon may cause hyperlemor of blood glucose, so higher insulin dose is needed.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

To be out of reach of children.

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