Medskin AcyClovir 200 DHG Pharma treated cases of herpes infection (5 blisters x 10 tablets)

Dosage form Box of 5 blisters x 10 tablets
Specifications Acyclovir

Ingredient

Composition information	Content
Acyclovir	200mg

Uses

Indications

Medskin 200 DHG 5X10 drugs are indicated in the following cases:

The initial treatment and prophylaxis for the herpes simplex type 1 and 2 virus in the skin and mucosa, Herpes Simplex. Beans in immunodeficiency, chickenpox in infants. Acyclovir has the strongest effect on the herpes simplex type 1 virus cell (HSV-1) and gradually decreases on Herpes Simplex Typ 2 (HSV-2) and Varicella Zoster virus (VZV), Cytomegalovirus (CMV).

Acyclovir works well in the treatment of severe HSV-1 viruses, the mortality rate can be reduced from 70% to 20%, among the patients being cured, serious complications also decrease.

pharmacokinetics

Oral bioavailability is about 10-20%. Acyclovir is used to be absorbed mainly through the intestine, the food does not affect the absorption of the drug. Acyclovir is widely distributed in body fluids and organs such as brain, kidneys, lungs, intestines, liver, spleen, uterus, mucosa, vaginal fluid, tears, aquatic fluid, semen, brain fluid. Acyclovir cohesion ratio with low protein 9 - 33%. The time to reach the peak concentration in plasma is 1.5 - 2 hours, the sale time is from 2-3 hours. Only a small amount of drugs are metabolized in the liver, and mostly excreted through the kidneys in the form of unchanged.

Before taking Medskin AcyClovir 200 DHG Pharma treated cases of herpes infection (5 blisters x 10 tablets)

How to use

Oral drugs.

Dosage

Treatment of Herpes Simplex infection

Adults and children over 2 years old

Take 1 capsule x 5 times/day, each time 4 hours apart. Use for 5 - 10 days.

prevention of recurrent herpes simplex for immunodeficiency people, internal transplants must take immunosuppressive drugs, HIV -infected people, chemotherapy users

Adults and children over 2 years old

Take 1 - 2 capsules 4 times/day.

Chickenpox and shingles treatment

Adults

Take 4 capsules x 5 times/day, in 7 days.

Children

Take 20mg/kg body weight x 4 times/day, for 5 days.

Patients with kidney failure

Oral: Dosage and number of drinks must vary depending on the degree of kidney damage.

Adjusting the dose in kidney failure:

The usual dose Creatinine clearance (ml/minute) Adjustable dose

400mg, 12 hours apart. Dose.
800mg, Early 8 hours apart.

Additional 1 dose immediately after each hemolysis.

Dosage for oral kidney disease with HIV infection

Creatinin clearance (ml/minute)

How to use hour. Si.

Read the user manual carefully before use.

This drug is only used by a doctor. If you need more information, please consult your doctor.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms

There is precipitate in the renal tubules when the renal tubules are exceeding 2.5mg/ml, or when high serum creatinine, kidney failure, stimulating state, restlessness, tremor, convulsions, chest drums, high blood pressure, difficulty urinating.

Treatment

Hematopathy of patients until kidney function recovers, stops drugs, gives water and electrolytes.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Medskin 200 DHG 5X10, you may experience unwanted effects (ADR).

Rare, including:

Digestive: Nausea, vomiting, diarrhea, abdominal pain, anorexia, digestive disorders.

Hematology: Anemia, leukemia, lymphadenitis, thrombocytopenia. Platelet hemorrhage, hemolysis syndrome hyperiemia, sometimes leads to death that has occurred in patients with immunodeficiency in high doses of acyclovir.

Central nerve: headache, dizziness, agitation. Less common are neurological or mental reactions (sleeping, tremor, mixed, hallucinations, epilepsy). skin: rash, itching, urticaria. other reactions: fever, pain, liver test, hepatitis, jaundice, muscle pain, angioedema, hair loss.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Medskin 200 DHG 5X10 drugs contraindicated in the following cases:

Hypersensitivity to any ingredients of the drug.

Caution when using

Persons of kidney failure.

Pregnant, lactating women.

The ability to drive and operate machinery

The drug does not affect the ability to drive and operate machinery.

Pregnancy

Be cautious when used.

breastfeeding period

Precautions when using.

Drug interaction

Simultaneous use Zidovudin and Acyclovir can cause a state of sleep and drowsiness.

Probenecid inhibits competition to eliminate acyclovir through the renal tubules, reduces excretion through urine and purification acyclovir.

amphotericin B and ketoconazole increase the anti -virus effect of acyclovir.

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding light.

Other drugs

Disclaimer

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