Mekocefaclor 250mg Mekophar treat sore throat, bronchitis, admidan (1 blister x 12 tablets)

Dosage form Box of 1 blister x 12 tablets
Specifications Cefaclor

Ingredient

Composition information	Content
Cefaclor	250mg

Uses

Indications

Mekocefaclor 250mg is indicated in the following cases:

Treatment of respiratory infections caused by sensitive bacteria (especially cases of failure after using conventional antibiotics). (cystitis). Bacterial cell formation. The following bacteria strains are sensitive to cefaclor:

Aerobic bacteria, grams:

Staphylococcus (including penicillinase enamel formation, positive coagulase, negative coagulase). Influenzae (including enzyme B - lactamase, ampicillin resistance), Klebsiella spp., Neisseria gonorrhoeae, Proteus Mirabilis.

Anaerobic bacteria: Bacteroides spp. (Except for Bacteroides Fragilis), peptococcus niger, peptostreptococcus sp.

pharmacokinetic

cefaclor is well absorbed after drinking. The average peak concentration in plasma is about 7 and 13 micrograms/ml, achieved after 30 to 60 minutes. The half -life of Cefaclor in plasma from 30 to 60 minutes. About 25% Cefaclor binds to plasma proteins.

Cefaclor is widely distributed throughout the body, passes through the placenta and excreted in low concentrations.

Cefaclor quickly excreted through the kidneys, up to 85% of the doses of use are eliminated through the urine in the form of unchanged within 8 hours, most of the excretion in the first 2 hours. A little cefaclor is excreted through hemorrhage.

Before taking Mekocefaclor 250mg Mekophar treat sore throat, bronchitis, admidan (1 blister x 12 tablets)

How to use

mekocefaclor 250mg is used orally.

Dosage

Adults:

Common dose: Take 1 tablet, every 8 hours. Maximum 4g/day.

Children ≥ 25kg:

Common dose: Take 20 - 40mg/kg body weight/24 hours, divided into 2-3 times.

If the clearinine clearance 10 - 50ml/minute: use 50 % of the usual dose. Patients must be clinical: The starting dose of 1-4 tablets before the hemorrhage and maintenance of treatment dose 1-2 tablets, 6 - 8 hours once, during the time between the separation.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? The severity of epigastric pain and diarrhea related to the dose.

Management:

There is no need to wash the stomach - intestines, unless you have taken Cefaclor at a dose of 5 times more than normal.

What to do when forgetting a dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using MekoceFaclor 250mg, you may experience unwanted effects (ADR).

Common: Eosin leukemia, diarrhea, measles skin rash.

Uncommon: Test Coombs directly positive, increase lymphocytes, leukopenia, neutrophils, nausea, vomiting, itching, urticaria, genital itching, vaginitis , fungal disease Candida .

Rare: Anaphylaxis, fever, symptoms like serum, Stevens - Johnson syndrome, poisoned epidermal necrosis, pus skin rash. Thresses, hemolytic anemia. Fake colitis. Increase liver enzyme, hepatitis, jaundice. Interstitial nephritis, slightly increased blood urea or serum creatinine or abnormal urine tests. The seizure, agitation, headaches , restlessness, insomnia, confusion, tone of force, dizziness , hallucinations and chicken sleep. Joint pain.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using MekoceFaclor 250mg, you need to read the instructions carefully and refer to the information below.

Contraindicated

Mekocefaclor 250mg contraindications in the following cases:

Hypersensitivity to cefaclor or other antibiotics belonging to cephalosporin, penicillin.

Caution when using

Caution when taking Cefaclor for patients with a history of allergies, impaired renal function, gastrointestinal diseases, especially colitis.

The safety and effectiveness of Cefaclor in children under 1 month of age has not been determined.

If allergic symptoms must be stopped with cefaclor. When necessary, appropriate therapy must be applied.

Photos aimed at driving and operating machinery

Caution when used for train drivers or operating machines.

Pregnancy and nursing mothers

Be cautious when taking cefaclor for pregnant or nursing women.

Drug interaction

simultaneously used with warfarin rarely causes increased prothrombin time, causing bleeding or not clinically bleeding.

Probenecid increases the concentration of cefaclor in serum.

Concentrated with aminoglycoside antibiotics or Furosemide diuretic gums increases the toxicity of the kidneys.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

To be out of reach of children.

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Disclaimer

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