Meloxicam Stada 7.5mg pain relief NSAIDS group (5 blisters x 10 tablets)

Dosage form Box of 5 blisters x 10 tablets
Specifications Meloxicam

Ingredient

Composition information	Content
Meloxicam	7.5mg

Uses

Indications

Meloxicam drug 7.5mg is indicated in the following cases:

Treatment of rheumatoid arthritis, treatment of short -term symptoms of severe acute osteoarthritis and treat symptoms of vertebrae. With anti -inflammatory properties, analgesic, fever. Meloxicam's anti -inflammatory ability has been shown by the classic models of inflammation. Like other NSAIDs, the main mechanism of its activity is still unknown.

However, at least one usual mechanism for all NSAIDs (including Meloxicam): Prostaglandin biosynthesis, is known as inflammation intermediaries.

pharmacokinetic

Meloxicam is well absorbed after drinking. The drug is 99% connected to plasma proteins.

Meloxicam has a half -life for about 20 hours.

The drug is metabolized mainly through oxidation and is excreted an equivalent amount through urine and feces, less than 3% of the dose is excreted in constant form.

Increased distribution volume when kidney failure.

Before taking Meloxicam Stada 7.5mg pain relief NSAIDS group (5 blisters x 10 tablets)

How to use

Meloxicam drug 7.5mg is taken orally.

Dosage

Rheumatoid arthritis and vertebral stiff inflammation: Normal single dose is 15mg/day.

People with high risk of side effects, should start at a dose of 7.5mg/day. Long -term treatment in the elderly: 7.5mg/day.

Severe acute osteoarthritis: Meloxicam's daily dose is 7.5mg, if necessary to increase to the maximum of the only dose of 15mg/day.

Smooth arthritis in adolescents for children 2 years and older: The usual oral recommended dose is 125mcg/kg/time/day, increasing to a maximum dose of 7.5mg/day.

BY BY BY AREA AS TO THE 12 to 18 years of tolerance of other NSAIDs:

less than 50kg: 7.5mg/time/day.

over 50kg: 15mg/time/day.

Used in people with kidney failure

Meloxicam is often contraindicated in patients with severe renal impairment. However, in patients with jurors, Meloxicam can be taken at a maximum dose of 7.5mg/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Gastrointestinal bleeding can occur. Some cases of severe poisoning can lead to hypertension, acute renal failure, liver dysfunction, respiratory failure, coma, convulsions, heart failure and cardiac arrest. Anaphylactic reactions have been reported when taking oral nsaids and can occur when overdose.

Patients need to be controlled for symptoms and supportive treatment when overdosing NSAID. Can quickly eliminate Meloxicam by using 4G cholestyramin orally 3 times/day.

What to do when forgetting a dose? If it is nearly time to take the next dose, skip the forgotten dose and take medicine at the next recommended dose. Do not take double dose to compensate for the forgotten dose.

Side Effects

When using Meloxicam 7.5mg, you may experience unwanted effects (ADR).

Very common

indigestion, nausea, vomiting, abdominal pain, constipation, flatulence, diarrhea.

Common

Headache.

Less

Gastrointestinal hemorrhage, stomatitis, gastritis, belching, anemia, dizziness, chicken sleep. Itching, rash, blushing, increasing transaminase or bilirubin.

Rare

colitis, stomach cancer, esophagus, Stevens-Johnson syndrome, urticaria, allergic reactions or hypersensitivity reactions, chest drums, tinnitus, light sensitive reactions.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Meloxicam drug 7.5mg contraindicated in the following cases:

Hypersensitivity to Meloxicam or any ingredients of the drug. Blood.

Precautions when using

influence on the gastrointestinal tract

The risk of serious effects on the gastrointestinal tract (such as bleeding, ulcers, perforation), may occur at any time when there is or without warning signs and symptoms.

Combined treatments may increase the risk including a history of bleeding or gastrointestinal ulcers, long -term treatment with NSAID drugs, anticoagulant or oral corticosteroid drugs, smoking, alcoholism, poor health conditions or in the elderly (risk of dangerous digestive tract complications).

High blood pressure

Using NSAID drugs, including Meloxicam, causes high blood pressure onset or adds to existing high blood pressure, this case increases the incidence of cardiovascular disease.

Effects on the kidneys

Nephrotic necrosis or renal marrow changes may occur when long -term use NSAID.

Hypersensitivity reaction

Hypersensitivity reactions include anaphylactic reaction that may occur in patients without the sensitivity to the previous Meloxicam.

Serious skin reactions (such as peeling dermatitis, Stevens-Johnson syndrome, poisoned epidermal necrosis) can occur in patients using Meloxicam.

Hematology influence

Anemia has been reported, mainly occurring in patients using long -term meloxicam (about 6 months).

The ability to drive and operate machinery

No specialized research on driving and operating machinery.

Pregnancy

Avoid taking the drug in the last 3 months of pregnancy because of the ability to close the fetal arterioscleros.

Breastfeeding period

Meloxicam excreted in milk in mice, should stop breastfeeding or stop taking the drug because the risk of finding hidden breastfeeding.

Medicinal interaction

NSAID and acetylsalicylic acid ≥ 3 g/day

Combined with other nonsteroidal anti -inflammatory drugs, including acetylsalicylic acid with anti -inflammatory doses (single doses> 1g or total daily dose> 3G) is not specified.

corticosteroid

Should be cautious when used with corticosteroids because of the increased risk of bleeding or stomach ulcers.

anticoagulant or heparin prescription for the elderly or at the dose

Increases the risk of bleeding, through platelet function inhibits and destroying the gastroesuit.

Diuretics, Inhibition of Move and Angiotensin II

NSAID drugs can reduce the effects of diuretics and other anti -hypertension drugs.

Other anti -hypertension drugs (such as beta blockers)

Like these drugs, reducing the hypotension effect of beta blockers (due to prostaglandin inhibitors with vasodilation effects) may occur.

cyclosporin

Cyclosporin's kidney toxicity may increase when using NSAIDs through prostaglandin intermediate effects.

lithium

NSAID drugs are reported to increase the concentration of lithiums in the blood (through the reduction of excretion in the kidneys), this can reach toxic value.

methotrexate

NSAID drugs can reduce the secretion of methotrexate in the renal tubules due to increased methotrexate levels in plasma.

cholestyramin

Cholestyramin increases the elimination of meloxicam by preventing the liver -intestinal cycle, so the clearance of Meloxicam increases by 50% and the selling time decreases to 13 ± 3 hours.

Storage

In closed packaging, dry place, avoid moisture. The temperature does not exceed 30 ° C.

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