Metformin 850mg TV.Pharm treatment for diabetes (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Metformin HCl

Ingredient

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Composition information	Content
Metformin HCl	850mg

Uses

indications

Metformin 850 mg drug is indicated in the following cases:

Treatment of insulin -dependent diabetes (type II): Single therapy, when unable to treat blood glucose with a simple diet. Enough.

pharmacokinetics

No data.

Before taking Metformin 850mg TV.Pharm treatment for diabetes (10 blisters x 10 tablets)

How to use

oral tablets. Swallowing the tablet, not chewing, drinking at meals.

Dosage

Adults: The normal starting dose is taking 1 tablet of 500 mg or 850 mg, taking 2 times a day (taking breakfast and dark meals, during or after eating). Once a week, an increase of 1 tablet daily to a maximum of 2500 mg/day. Doses up to 2000 mg/day can be taken twice a day. If necessary, take a dose of 2500 mg/day divided into 3 times a day at a meal for better tolerance.

Elderly: The starting dose and maintenance dose need to be reserved because there may be a impaired renal function. In general, elderly patients should not treat the maximum dose of metformin.

Children: Although rare. Metformin dose for children from 10 to 16 years old is 500 mg once, 2 times a day at breakfast and dinner. Every week, an increase of 1 tablet. The maximum dose is 2g/day divided into 2 or 3 times. Continue to take Metformin at maximum dose. If after 3 months of treatment for coordination of metformin and sulfonylurea, inadequate response, it is advisable to consider switching to using insulin with or not included Metformin (the combination of drugs for the goal of lowering blood glucose, refer to the treatment guidelines of the Ministry of Health of Vietnam and the International Diabetes Association (IDF).

Coordinate with insulin: Metformin can be combined with insulin to achieve better blood sugar control. The usual starting dose of Metformin is 1 tablet of 500 mg or 850 mg, 2-3 times daily, and the dose of insulin is adjusted depending on blood sugar.

During the treatment of diabetes, the dosage of the drug must be adjusted based on the response and tolerance of the patient. The goal of treatment is to reduce blood sugar at less than 126 mg/decilite (

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

In case of emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double doses to compensate for missed dose.

Side Effects

When using the drug, there are common unwanted effects (ADR) such as:

Common: Gastrointestinal disorders can be up to 27%, may experience abdominal pain, vomiting, appetite, gastritis, constipation, chest pain (8%), angioedema (4%), hypertension (4%), headache (3 - 8%), dizziness (2 - 6%), fatigue (3%), painful pain (6%), itching (iron) (3%). Sac, pleural bleeding, hepatitis, interstitial pneumonia, intracranial bleeding, ischemic necrosis, intraocular bleeding, pancreatitis, Stevens-Johnson syndrome, platelet reduction, thrombocytopenia, toxic skin necrosis, vasculitis, severe neutrophils.

Notify the physician with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Metformin 850 mg drug is contraindicated in the following cases:

Patients with serious complications, bacterial infections, trauma (must be treated with diabetes with insulin). Hemorrhage causes. Calculate. Kidney.

Be cautious when using

need to be very careful when taking the drug for patients in the following cases:

For patients using metformin, regular subclinical tests should be monitored, including blood sugar quantitative, to determine the minimum metformin dose effective. Patients need information about the risk of lactic acid infection and circumstances that can easily lead to this condition.

metformin is excreted mainly through the kidneys, the risk of accumulation and lactic acid infection increases according to the degree of renal function.

Metformin is not suitable for treating the elderly, often with impaired renal function; Therefore, serum creatinine must be checked before starting treatment.

Must stop treatment with Metformin from 2-3 days before the scanning.

There is a notice that the use of diabetes treatments increases cardiovascular mortality, compared to a simple diet treatment or insulin combination with a diet.

Metformin must be stopped when performing surgery.

Do not use metformin in patients with liver function impairment.

Be cautious when used for children aged 10 to 12 years old.

The effect of the drug on the ability to drive and operate machinery

Metformin single treatment does not lower blood sugar and therefore did not affect the ability to drive or use machinery.

When metformin is used in combination with other diabetes (such as sulfonylurea, insulin, meglitinides), should be cautious about using drugs for trainers and operating machinery.

Use drugs for women during pregnancy and lactation

pregnancy:

metformin is contraindicated for pregnant women.

breastfeeding period:

metformin is excreted in breast milk. No side effects are observed in infants and infants breastfeeding. However, limited data, need to consider whether to stop breastfeeding or stop taking the drug, based on the importance of the drug for the mother.

Drug interaction

Active reduction: drugs that tend to cause hyperglycemia (for example, diuretics, corticosteroids, phenothiazine, thyroid preparations, estrogen, oral medications, phenytoin, nicotine acid, drugs that are similar to sympathetic neurons, calcium channel blockers, iSoniazids) Blood glucose.

Increased effect: Furosemid increases the maximum concentration of Metformin in plasma and in the blood, without changing Metformin's kidney clearance coefficient in the study using a single dose.

Increased toxicity: Cationic drugs (for example, amilorid, digoxin, morphine, process, Quinidin, Ranitidin, Triamteren, Trimethoprim and Vancomycin) are excreted by excretion through the renal tubules that can interact with Metformin by competing with conventional transportation systems in the kidney tubes. Cimetidine increases the peak concentration of Metformin in plasma and total blood, thus avoiding Metformin combination with cimetidine.

Interaction with alcohol: avoid or limit drinking alcohol (lactic acid infection rate may increase, can cause hypoglycemia).

Storage

Leave a cool place, avoid light, temperatures below 30⁰C.

To be out of reach of children, read the instructions carefully before use.

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