Methionin 250mg Domesco Treatment of Paracetamol overdose (100 tablets)

Dosage form Box of 100 capsules
Specifications Methionin

Ingredient

Composition information	Content
Methionin	250mg

Uses

indications

Methionin 250 mg is indicated in the following cases:

Paracetamol overdose treatment to prevent liver damage without acetylcysteine.

Pharmacokinus

methionine is an essential amine acid in the composition of the diet and in the formula of amine acid preparations to nourish. Methionine enhances glutathione synthesis and is used instead of acetylcysteine to treat paracetamol poisoning to prevent liver damage. Methionine is also used by oral to reduce urine pH and as a supportive drug in the treatment of liver dysfunction.

Pharmacokinetics

absorption

methionine is absorbed through the digestive tract.

Metabolism

Most methionine are metabolized in the liver into s-adenosylmethionine, homocysteine and other metabolites.

Elimination

methionine is excreted in urine in the form of inorganic sulfate.

Before taking Methionin 250mg Domesco Treatment of Paracetamol overdose (100 tablets)

How to use

oral medication. Take medicine at meals or when full.

Dosage

Paracetamol overdose treatment

It is necessary to conduct treatment within 10 to 12 hours after taking paracetamol.

Children 6 years of age and older and adults

The dose of 2.5 g/time, starting from the overdose of paracetamol, every 4 hours and 4 doses. Treatment depends on the concentration of paracetamol in plasma.

Children under 6 years old

The oral dose of 1 g/time, starting from the overdose of paracetamol, 4 hours from 4 hours and 4 doses.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

In case of an overdose that needs gastric wash, symptomatic treatment and support.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using 250 mg methionin, you may experience unwanted effects (ADR).

Nausea, vomiting, sleep, easily stimulated.

Causes metabolic acidosis and hyper nitrogen in people with renal function.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Methionin 250 mg is contraindicated in the following cases:

allergies to any ingredients of the drug.

Be cautious when using

In patients who have liver failure, methionine can cause further liver damage. Be careful when using methionine for people with severe liver disease.

In patients who have liver failure/liver damage, methionine can cause brain disease due to the liver progress. Do not use methionine to treat paracetamol poisoning if it is more than 12 hours from the time of overdose.

The ability to drive and operate machinery

methionine can cause chicken sleep. Therefore, caution when using drugs for patients driving and operating machinery.

Pregnancy

There is no research data on pregnant women.

Breastfeeding period

There is no research data on breastfeeding women.

Drug interaction

methionine can be absorbed by activated carbon.

methionine reduces the effect of dopamine derivatives like levodopa. High -dose methionine should be avoided in patients being treated with levodopa.

Storage

In a dry place, temperatures below 30ºC, avoid light.

Other drugs

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