Methycobal tablets 500µg Eisai treat peripheral neuropathy (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications mecobalamin

Ingredient

Composition information	Content
mecobalamin	500mcg

Uses

indications

Methycoban drug are indicated in the following cases:

Treatment of peripheral neuropathy.

Do not use the drug for more than 1 month unless the drug is effective.

Mecobalamin plays an important role in methyl transfer as a coenzym in the synthesis of methionine from Homocysteine. The synthesis of thymidine from deoxyuridine, increasing the use of folic acid is stagnant and increases nucleic acid metabolism.

mecobalamin enhances transportation through axon and axon regeneration:

Mecobalamin normates the transportation through the axon in the sciatica in the rats that has been caused diabetes with streptozotocin. In mice and neuropathy in rats with spontaneous diabetes.

Mecobalamin enhances the synthesis of lecithin is the main component of the lipid of the spinal cord and increases the myelin of nerve cells in mouse tissue culture better than Cobamamide.

mecobalamin recovers slow passage through synap and restores a reduction in neurotransmitter returning to normal:

Mecobalamin Early recovery can be found in the end by increasing the irritability of nerve fibers in sciatica cells that were pressed in rats.

Single dose:

After taking a single dose of 120 µg or 1500 µg, the highest total vitamin B12 level in the serum is achieved for both doses after 3 hours and depend on the dose. 40 - 90% of the total vitamin B12 accumulated in the water pepper 24 hours after the use has been exported within the first 8 hours.

The total vitamin B12 concentration in serum has been determined in those who take the methycobal doses of 1,500 µg/day for 12 consecutive weeks. In the beginning.

Before taking Methycobal tablets 500µg Eisai treat peripheral neuropathy (3 blisters x 10 tablets)

How to use

Methycobal 500mcg tablets are used by oral, can be taken with or without food, should adjust the dose according to patient age and symptoms.

Dosage

The usual dosage for adults is taking 3 capsules/day (1,500 mg of mecobalamin) divided 3 times, orally orally.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when using overdose? Specific antidote unknown.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using methycoban, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Not yet reported.

Uncommon, 1/1000

Digestive: reducing appetite, nausea/vomiting and diarrhea .

Skin and subcutaneous tissue: rash.

Neurology: headache .

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Methycobal drugs are contraindicated in the case of patients with a history of hypersensitivity to mecobalamin or any excipients.

Be cautious when using

General warning: Do not take the drug for months if not responded after a period of treatment.

Lactose and sucrose, patients with rare genetic problems galactose or fructose intolerance, Lapp lactase enzyme deficiency or glucose-galactose or lack of enzyme supply-Isomaltase should not be taken.

For medications in the click (PTP), it is necessary to guide the patient to remove the pills from the blister before use.

It is not recommended to use high -dose methycobal, prolonged for patients with occupational contact with mercury or mercury -containing compounds.

The ability to drive and operate machinery

Based on the pharmacological properties and reports on side effects, not sure that methycobal reduces the ability to drive or use machinery

pregnancy

has not set the safety data of methycobal tablets in pregnant women. This medication should only be used for pregnant women or women who are suspected of being pregnant if the treatment benefits are higher than any risk that may occur.

The period of breastfeeding

has not set data safely, only used when treatment benefits are higher than any risk that may occur.

Interactive drug

Medicines reducing the absorption of amino-Salicylic acid, chloramphenicol, colchicine, antihistamine-2, neomycin and proton pump inhibitors (omeprazole).

Reduce serum levels when used with birth control pills.

Response treatment reduces when using high doses of folic acid.

Methycoban is reduced if used with alcohol.

Storage

Store at room temperature no more than 30 ° C, avoid light and avoid moisture after opening the box.

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