Methylprednisolone 16mg USA - Nic Pharma anti -inflammatory and immunosuppressive, anti -allergic inhibition (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Methylprednisolone

Ingredient

Composition information	Content
Methylprednisolone	16mg

Uses

Indications

Methylprednisolone 16mg USA-NIC 3X10 is indicated in the following cases:

Anti -inflammatory in the following cases: rheumatoid arthritis, whole body lupus, temporal arteritis, button artery inflammation, sarcoid disease, bronchial asthma, colitis.

Immune inhibition: Hemolytic anemia, granulocytosis, acute leukemia, lymphoma, breast cancer, end-stage prostate cancer. marked.

Due to Prednisolon methylation, the effect of corticosteroids metabolizes salt has been excluded, so there is little risk of salt and edema. The anti -inflammatory effect of methylprednisolon increases 20% compared to the effect of Prednisolon.

Dynamic pharmacokinetics

bioavailability is approximately 80%. Plasma concentration reaches a maximum of 1-2 hours after taking the drug. Biological effect time (inhibiting pituitary gland) is about 1/2 days, can be considered a short effect. Methylprednisolon is metabolized in the liver, like metabolism of hydrocortison and metabolites are excreted in the urine. Half life is approximately 3 hours.

Before taking Methylprednisolone 16mg USA - Nic Pharma anti -inflammatory and immunosuppressive, anti -allergic inhibition (3 blisters x 10 tablets)

How to use

Oral drugs.

Dosage

must follow the doctor's instructions.

Starting dose

divided into 2-4 times a day.

Adults: 5 - 60mg/day.

Children: 0.14 - 2mg/kg/day.

Maintenance dose

divided into 2-4 times a day.

Adults: 5 - 15mg/day.

Children: 0.25 - 0.50mg/kg/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Not updated.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the forgotten dose and continue the calendar of methylpred nic 16mg. Do not use double dose to compensate for missed dose.

Side Effects

When using methylprednisolone 16mg USA-NIC 3x10, you may experience unwanted effects (ADR).

Electrolyte water disorders

alkaline blood due to hypokalemia, holding salt water leads to high blood pressure, congestion heart failure.

Endocrine and metabolic disorders

Cushing syndrome caused by drugs, discontinue ACTH excretion, adrenal shell atrophy, reduced glucose tolerance.

Bone muscular disorders

muscle atrophy, osteoporosis, spine subsidence, no infection bone malagism, ligament break.

Gastrointestinal disorders

Peptic ulcer, bleeding due to ulcers, small intestine ulcers, acute pancreatitis especially in children.

Skin disorders

Skin atrophy, slow scars, hemorrhage, bruises, acne mainly on the back, hair.

Mental disorders

excessive excitement when taking the drug, becoming depressed when stopping the drug.

Eye disorders

A few types of glaucoma, cataracts.

ADR management direction

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Methylprednisolone 16mg USA-NIC 3X10 contraindicated in the following cases:

Hypersensitivity to glucocorticoids.

Severe bacterial infections except for bacterial shock and meningitis.

Skin infections due to viral, fungi or tuberculosis.

Using a live virus vaccine.

Caution when using

Caution for patients with osteoporosis, newly connected to the intestine, blood vessels, mental disorders, stomach ulcers, diabetes, high blood pressure, heart failure, growing children, elderly people. Must always reduce the dose slowly, do not stop the drug suddenly.

Treatment lasts more than 6 months often causes cortisone deficiency due to ACTH restraint, so it should be noted when severe stress occurs when being treated or when the drug is stopped for months.

The ability to drive and operate machinery

Not used for drivers and operating machinery.

Pregnancy

Not for pregnant women.

Breastfeeding period

Not used for breastfeeding women.

Drug interaction

methylprednisolone is a cytochrom P450 enzyme induction and is the substrate of the P450 CYP 3A enzyme, so this drug inhibits the metabolic impact of ciclosporin, erythromycin, phenobarbitan, phenytoin, carbamepin, carbamepin, carbamere Ketoconazole, rifampicin.

Phenobarbitan, Phenytoin, Rifampicin, diuretics decreased blood potassium, reducing the effectiveness of methylprednisolone. Methylprednisolone causes hyperkalemia, so the higher insulin dose is needed.

Avoid simultaneous use of methylprednisolone with nonsteroidal anti -inflammatory drugs because it can cause stomach ulcers.

Storage

In a cool dry place (temperature

Other drugs

Disclaimer

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