Methylprednisolone MKP 16mg Mekophar anti -inflammatory, treat endocrine disorders, arthritis (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Methylprednisolone

Ingredient

Composition information	Content
Methylprednisolone	16mg

Uses

Indications

methylprednisolone MKP 16mg indicated in the following cases:

Methylprednisolone is indicated in nonspecific therapy requires anti -inflammatory and immunosuppressive effects of glucocorticoid for: rheumatoid arthritis, systemic erythema lupus, some forms of inflammation, temporal arteritis, inflammation around the artery, sarcoid disease, asthma, broccoli, chronic ulcerative, hypotension, and heavy hypoquenosis, and severe hypoignant, and severe allergens, and severe allergens including response, treatment Like acute Leukemia disease, lymphoma, breast cancer and prostate cancer. marked.

Dynamic pharmacy

bioavailability is approximately 80%. Plasma concentrations reach a maximum of 1-2 hours after taking the drug. Biological effect time is about 1.5 days, can be considered a short effect.

Methylprednisolone is metabolized in the liver, and metabolites are excreted in the urine. Selling time cancel approximately 3 hours.

Before taking Methylprednisolone MKP 16mg Mekophar anti -inflammatory, treat endocrine disorders, arthritis (10 blisters x 10 tablets)

How to use

methylprednisolone MKP 16mg Tablets for oral tablets.

Dosage

recommended dose:

Starting dose 4 - 48 mg/day depending on the type of disease. This dose should be maintained or adjusted the dose until there is response.

If treated for a long time should determine the lowest dose effectively. Reduce the dose slowly.

When you need to use big doses for a long time, apply medication therapy after day after control of the disease process. In daily therapy, use 1 single dose, every 2 days, in the morning according to the span of natural secretion glucocorticoid.

Treatment of severe asthma attacks for boarding people, after recovering from acute asthma:

Take the dose of 32 - 48 mg/day, then gradually reduce the dose and can stop the drug within 10 days to 2 weeks.

Acute asthma attacks: 32 - 48 mg/day x 5 days, then use lower doses for a week. The dose is gradually reduced when acute asthma attacks.

Severe disease: Start taking 0.8 mg/kg/day divided into small doses, then use 1 time/day, followed by gradually decreasing to the lowest dose to work.

Acute rheumatoid arthritis: 16 - 32 mg/day.

Chronic ulcerative ulcer, severe exacerbations: 8 - 24 mg/day.

Nephrotic syndrome: 0.8 - 1.6 mg/kg/day x 6 weeks, then gradually decrease the dose for 6 - 8 weeks.

Delted hemolytic anemia: 64 mg/day, at least 6-8 weeks.

Sarcoid disease: 0.8 mg/kg/day to improve the disease. Then use the maintenance dose low: 8 mg/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? When using too high doses for a long time, it may increase adrenal gland energy and inhibit the adrenal glands. In these cases, it is necessary to consider to make the right decision to suspend or stop using the drug.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

The most common effects occur most when using methylprednisolone high doses and long -term.

methylprednisolone inhibits prostaglandin synthesis and thus losing the effect of prostaglandin on the gastrointestinal tract, including inhibiting gastric acid secretion and protecting the stomach lining.

Common

Central nervous system: Insomnia, nervousness is easily agitated. Orange.

Uncommon:

Central nervous system: dizziness, convulsions, mental disorders, fake tumors in the brain, headache, mood change, delirium, hallucinations, refreshment. Glucose, reduced blood potassium, alkaline infection, amenorrhea, sodium and water, hyperglycemia Want to encounter when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Methylprednisolone MKP 16mg contraindications in the following cases:

Hypersensitivity to methylprednisolone or any ingredients of the drug.

Precautions when using

Acute adrenal enrollment may occur when stopping the drug suddenly after a long time of treatment or when stress.

Be cautious in people with osteoporosis, new blood vessels, mental disorders, stomach ulcers - duodenum, diabetes, hypertension, heart failure and growing children.

Use cautiously for the elderly, should be used in the lowest doses and in the shortest possible time.

High -dose corticosteroids can affect the effects of vaccines.

Be cautious when used for train drivers or operating machines, pregnant women and nursing.

Drug interaction

methylprednisolone MKP 16mg affects the metabolism of ciclosporin, erythromycin, phenobarbital, phenytoin, carbamazepin, ketoconzol, rifampicin.

Phenytoin, Phenobarbital, Rifampicin and diuretics decreased potassium can reduce the effectiveness of methylprednisolone.

methylprednisolone may cause increased blood glucose, so higher insulin dose.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

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Disclaimer

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