Metronidazole 250mg Mekophar tablets for treating genital tract infections, amoeba disease (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Metronidazole

Ingredient

Composition information	Content
Metronidazole	250mg

Uses

Indications

metronidazole 250mg Indications for treatment in the following cases:

Trichomonas vaginalis infection in the urinary tract - genital. Red. Learning

metronidazole, nitro-imidazole derivative, has the effect of treating protozoa infections such as Entamoeba Histolytica, Giardia Lamblia, Trichomonas Vaginalis and has bactericidal effect on Bacteroides, Fusobacterium and other aerobic bacteria for other nuclear bacteria. Metronidazole is only resistant to a few cases.

Dynamic pharmacy

Metronidazole is often absorbed quickly and completely by oral, reaching a plasma concentration of approximately 10kg/ml about 1 hour after oral 500mg. About 10 - 20%

Metronidazole binds to plasma proteins. Metronidazole diffuses well into tissues and fluids, saliva and breast milk. Metronidazole metabolizes the liver into hydroxy and acid conversion substances, excreted through urine partially in the form of glucuronid.

Before taking Metronidazole 250mg Mekophar tablets for treating genital tract infections, amoeba disease (10 blisters x 10 tablets)

How to use

Take or after meals.

Dosage

Amoeba treatment

A wave of use from 5–10 days

Adults: Take 6– 9 capsules/day, divide 3 times.

children: Take 35– 50mg/kg/day, divide 3 times.

Disease by trichomonas urinary - genital:

Need treatment for both partners. There are 3 treatments:

Take a single dose of 2g (8 capsules), in the evening before going to bed

or use 7 days: take 1 tablet x 3 times/day

or use 10 days:

Male: Take 1 capsule 2 times/day

Women: take 1 capsule 2 times/day and order more

1 egg/vaginal tablet in the evening before going to bed.

Giardia disease:

Adults: Take 1 time 2g/day for 3 days

or 1 tablet x 3 times/day for 5–7 days.

Children: take 15mg/kg/day, divide 3 times in 5–10 days.

Anaerobic infection treatment

Adults: Take 7.5mg/kg (maximum 1g), every 6 hours, used for 7 days or longer.

Children: Take 7.5mg/kg, every 8 hours.

H.pylori infection treatment

500 mg x 3 times/day, in combination with bismuth compounds or proton pump inhibitors and other antibiotics (clarithromycin or amoxicillin) for 1-2 weeks.

Prevention of anaerobic infection after surgery

20– 30mg/kg/day, divided into 3 times. Often coordinated with antibiotics B - lactam or aminoglycoside.

What to do when using overdose? Symptoms include nausea, vomiting and loss of air conditioning. The nerve effect of convulsions, peripheral neuritis has been reported after 5–7 days of dosage; 6 - 10.4g 2 days/time.

Treatment: There is no specific antidote. Symptomatic treatment and support.

What to do if you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Metronidazole common effects (ADR) such as:

Common: Nausea, vomiting, anorexia, abdominal pain, diarrhea , with uncomfortable metal taste. encountered when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Metronidazole contraindicated in the following cases:

Hypersensitivity to nitro-imidazole or one of the ingredients of the drug.

Be cautious when using

Stop therapeutic when losing air conditioning, dizziness or mental disorders.

The drug can aggravate the nerve state in people with the disease in the central nervous system or severe, stable or progressive peripheral system.

Monitor leukemia formulas in people with a history of blood disorders or high and prolonged doses.

Need to reduce the dose in people with severe liver failure.

Metronidazole has the effect of inhibiting alcohol Dehydrogenase and other alcohol oxidation enzymes.

The disulfiram -like mild reactions such as hot face, headache, nausea, vomiting, abdominal spasms and sweating. Do not drink alcohol, alcoholic beverages during medication.

Metronidazole can cause immobility of Treponema Pallidum to create a false positive reaction of the Nelson test.

The effect of the drug on the ability to drive and operate machinery

Caution when using the drug for drivers and operating the machine.

Using drugs for women during pregnancy and lactation

Do not use drugs for pregnant women in the first 3 months of pregnancy, cautious when taking drugs for pregnant women in the last 6 months of pregnancy.

Metronidazole is excreted in breast milk, nursing women should stop breastfeeding when treated with Metronidazole.

Medicinal interaction

metronidazole increases the effect of anticoagulant oral drugs, especially warfarin, so avoid use at the same time.

metronidazole has a disulfiram -style effect. So do not use these two drugs simultaneously to avoid nervous effects such as psychosis, confusion.

Simultaneous use of metronidazole and phenobarbital increases metronidazole metabolism so Metronidazole is faster. Use Metronidazole for patients with high blood lithium concentrations (because they are using lithium) will increase the concentration of lithium lithium increased, toxic.

metronidazole increases the effect of vecuronium is a non -reducing muscle relaxant.

To avoid interactions between drugs, notify the doctor or pharmacist about the drugs being used.

Storage

Leave in a dry place, avoid light, the temperature does not exceed 30 degrees C.

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