Metronidazole Stella 400mg medicine for fungal infection and anaerobic infection (2 blisters x 7 tablets)

Dosage form Box of 2 blisters x 7 tablets
Specifications Metronidazole

Ingredient

Composition information	Content
Metronidazole	400mg

Uses

Treatment of sensitive protozoa such as Trichomonas infection, amoeba infection, balantidium disease, Blastocystis hominis infection, Giardia infection, dragon worm Drucunculus.

Treatment and prevention of anaerobic infection. Characteristic infections such as gynecological infections, acute necrotic gum ulcer, pelvic infection and antibiotic colitis.

Treatment of gastrointestinal ulcer caused by Helicobacter pylori (combined with other drugs).

Before taking Metronidazole Stella 400mg medicine for fungal infection and anaerobic infection (2 blisters x 7 tablets)

How to use

Take medicine at the same time or after meals.

Dosage

Trichomonas infection

The only dose of 2 g or a 7 -day treatment includes 250 mg x 3 times/day.

In addition, you should treat your partner.

Awesome disease

Grade -class dysentery in the intestine by E. Histolytica:

Adults: 750 mg x 3 times/day for 5-10 days.

Children: 35 - 50 mg/kg/day, divided into 3 times, for 5 - 10 days.

liver abscess due to amoeba:

Adults: 500 - 750 mg x 3 times/day for 5 - 10 days or 1.5 - 2.5 g x 1 time/day for 2 or 3 days.

Children: 35 - 50 mg/kg/day, divided into 3 times, for 5 - 10 days.

Balantidium disease and blastocystis hominis infection:

750 mg, 3 times/day, for 5 - 10 days.

Giardia disease:

Adults: 2 g x 1 time/day, for 3 consecutive days or 250 mg x 3 times/day, for 5-7 days.

Children: 15 mg/kg/day divided into 3 times in 5-7 days.

Dracunculus dragon worm disease:

Adults: 250 mg x 3 times/day or 25 mg/kg/day for 10 days.

Children: 25 mg/kg/day for 10 days. Not more than 750 mg/day (although children over 30 kg).

Anaerobic infection:

7.5 mg/kg, until 1 g, every 6 hours in about 7 days or longer.

Gynecological infections:

The only dose of 2 g or a 5-7 -day treatment with 500 mg 2 times/day.

Acute necrotic gum ulcer:

250 mg x 3 times/day for 3 days; The same dose is used in acute oral infections.

Antibiotic colitis:

500 mg x 3 - 4 times daily.

Pelvic inflammation:

500 mg x 2 times/day is combined with ofloxacin 400 mg 2 times/day; Continuous treatment for 14 days.

Prevention of anaerobic infection after surgery:

20 - 30 mg/kg/day divided into 3 times.

Digestive ulcer caused by H. pylori:

500 mg x 3 times/day in combination with at least one other drug with H. pylori elimination (such as bismuth subsalicylat, amoxicillin ...) for 1-2 weeks.

Hepatic failure:

Because metronidazol is metabolized mainly by the oxidation of the liver, the accumulation of metronidazol and the metabolites may occur in patients with severe liver function impairment. Therefore, Metronidazole should be used with caution and reduce the dose for patients with severe liver failure, especially the liver's enhancement when the adverse effects of Metronidazol may increase the symptoms of the disease. You can use 1/3 of the usual daily dose 1 time/ day for these patients. For patients with lighter liver failure, pharmacokinetic studies do not give constant results and no recommendations on dose reduction.

kidney failure:

Metronidazole elimination is largely unchanged in patients with renal impairment, although metabolites can accumulate in patients with end -stage renal disease being separated. Therefore, it is often not recommended to reduce the dose for patients with renal impairment. Because both Metronidazol and metabolites are removed by hemorrhage, the medication must be used immediately after hemorrhage.

or according to the doctor's instructions.

What to do when overdose?

In case of emergency, call the Emergency Center 115 or the nearest medical station.

What to do if you forget 1 dose?

If you forget a dose, use it as soon as possible. However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

Common

Nausea, vomiting, anorexia, abdominal pain, diarrhea and an unpleasant metal taste.

Uncommon:

leukopenia.

Rare:

loss of granulocytes; Epilizer type seizures, peripheral neuropathy, headache; Diverse roses, skin rash, itching; Dark urine.

Warnings

Precautions when using

Metronidazol has the effect of inhibiting alcohol Dehydrogenase and other alcohol oxidation enzymes. Disulfiram -style mild reactions such as hot face, headache, nausea, vomiting, abdominal spasms and sweating.

should monitor clinical and test for more than 10 days.

metronidazol should be used carefully and reduce the dose in patients with severe liver failure. Metronidazole should be monitored in plasma in these patients.

Pregnant women: Metronidazole through the placenta fence and quickly penetrate the fetal circulation.

There is no adequate and well -controlled research on the use of Metronidazol in pregnant women, so they only use drugs during pregnancy when they are really necessary.

Do not use medication for women in the first 3 months of pregnancy (see contraindicated).

Weeding women: Metronidazol is excreted through breast milk with the concentration of drugs equivalent to the concentration found in plasma.

Because the tests show that Metronidazole has the potential to cause cancer in mice and rats, so there is a decision to stop breastfeeding or stop taking the drug, considering the importance of the drug for the mother.

Influence on the ability to drive and operate machinery: Patients should be warned of the possibility of drowsiness, dizziness, confusion, hallucinations, convulsions or visual disorders and are advised not to drive or operate machinery if these symptoms occur.

Drug interaction

Coumarin anticoagulant drugs. Do not use with sulfiram. Abstain from wine.

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding light

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