MEXCLD 650 Imexpharm tablets reduce fever pain (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Paracetamol

Ingredient

Composition information	Content
Paracetamol	650mg

Uses

indications

MEXCLD 650 drug is indicated in the following cases:

Treatment of pain symptoms such as headache, toothache, muscle aches, dysmenorrhea, rheumatism. The drug acts on the hypothalamus causing cooling, increasing heat due to vasodilation and increasing peripheral blood flow.

Paracetamol with a low dosage that affects the cardiovascular and respiratory system, does not change acid -base balance, does not cause irritation, scratches or stomach bleeding as when using salicylate because paracetamol does not work on the body cycloxygenase, only affects cycloxygenasel prostaglandin of the central nervous system. Paracetamol does not work on platelets or bleeding time.

paracetamol reduces body temperature in fever but rarely reduces body temperature in normal people. When overdose is used, the metabolic substance will be N - Acetyl - Benzoquinoimin, which is severe toxic to liver cells.

Dynamic pharmacokinetics

Paracetamol is absorbed quickly and almost completely through the gastrointestinal tract, the peak concentration in plasma is achieved within 30 - 60 minutes after drinking with the dose of treatment.

Paracetamol is distributed quickly and evenly in most body tissues. About 25% paracetamol in the blood combined with plasma proteins. Paracetamol is metabolized mostly in the liver and excreted mainly through urine in the form of an associated with glucuronic acid.

Sell waste time is about 1.25 - 3 hours, can last for toxic doses or patients with liver damage.

Before taking MEXCLD 650 Imexpharm tablets reduce fever pain (10 blisters x 10 tablets)

How to use

MEXCLD 650 drugs are used by oral.

Dosage

Adults and children over 11 years old

Take 1 capsule/time, every 4-6 hours when needed. Do not drink more than 4 g/day.

Paracetamol content in Mexcold 650 movie tablets is not suitable for children under 11 years old.

Do not use paracetamol to treat pain for more than 10 days in adults or more than 5 days in children, unless the physician is instructed.

Do not use paracetamol for adults and children to treat high fever by themselves (above 39.5 ° C), fever lasts for more than 3 days or recurrent fever, unless it is indicated by a physician.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms of overdose:

Nausea, vomiting, abdominal pain, anorexia, blood methemoglobin leading to purple blue, mucous and nail.

Early diagnosis is very important in the treatment of paracetamol overdose. Acetylcystein is more effective when giving the drug for less than 10 hours after taking paracetamol.

Side Effects

When using MexCLD 650, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Skin: Red or urticaria, but sometimes worse and may be accompanied by drugs and mucosal lesions.

The digestive system: Nausea, vomiting.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

MEXCLD 650 drug contraindicated in the following cases:

Sensitive to paracetamol or any ingredients of the drug.

Patients with anemia many times.

Heart disease, lung disease, liver failure, renal failure.

Patients with glucose deficiency - 6 - Phosphate dehydrogenase.

Caution when using

paracetamol is relatively non -toxic at the dose of treatment. Sometimes skin reactions include lumpy, itchy and urticaria, other hypersensitivity reactions including larynx edema, angioedema and anti -summary reactions. Neutral leukopenia and thrombocytopenic decrease occur when using paracetamol.

Rarely loss of granulocytes in patients using paracetamol. Using paracetamol carefully in patients with anemia before because purple blue may not manifest clearly, although there are dangerous high concentrations of methemoglobin in the blood. Drinking plenty of alcohol can cause toxicity to the liver of paracetamol, should avoid or limit drinking.

Use carefully with people with impaired liver or kidney function.

Doctors need to warn patients on signs of serious skin reactions such as: Stevens - Johnson syndrome (SJS), Poisoned Skin necrotic syndrome (Ten) or Lyell syndrome, acute overseas pustular syndrome (AGEP).

The ability to drive and operate machinery

The drug does not affect the ability to drive train and operate machinery.

Pregnancy

only use paracetamol for pregnant women when really necessary.

The period of breastfeeding

Research in the mother using paracetamol, has not seen unwanted effects in breastfed babies. Be careful when using paracetamol for this object.

Drug interaction

Long -term oral high doses of paracetamol increases the anticoagulant effect of COMAARIN and indandion derivatives. This effect seems to be little or not important in clinical. It is necessary to pay attention to the possibility of serious antipyretics in patients using simultaneously phenothiazine and cooling therapy.

Out of alcohol too much and long may increase the risk of paracetamol toxic to the liver.

Anti -seizure drugs (phenytoin, barbiturat, carbamazepin): Causes the enzyme induction in the liver microsom, increases paracetamol metabolism into toxic substances to the liver.

Coordination with Isoniazid also causes increased liver toxicity.

Storage

less than 30 ° C, avoid moisture and light.

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