Meyer Vita DC Memora Memora Treatment and Prevention of Vitamin D and Calcium deficiency, osteoporosis (20 packs)

Dosage form Nuggets
Specifications Box of 20 packs
Ingredient Vitamin D3, Calcium

Ingredient

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Composition information	Content
Vitamin D3	800iu
Calcium	1.2g

Uses

indications

Meyer Vita DC medicine is indicated for adults and the elderly in the following cases:

Treatment and prevention of vitamin D and calcium deficiency.

ATC code: A12AX.

Meyer Vita DC is a drink used for oral, combining tricaliCi phosphate with Colecalciferol (vitamin D3).

calcium and vitamin D have a basic effect on bone regeneration process, so used in elderly people with negative calcium balance with low vitamin D concentration and high hormone hormones (PTH). This secondary hyperthyroidism is effectively adjusted by the combination of tricalci phosphate and vitamin D, in Meyer Vita DC preparations.

Vitamin D, which maintains normal calcium and phosphorus concentrations in serum, helps increase calcium absorption in the small intestine.

pharmacokinetics

absorption:

About 30% of calcium is absorbed in the small intestine. Vitamin D is also absorbed quickly in the intestine after drinking. The bile is essential for the absorption of vitamin D in the intestine. Currently, it is unclear whether old age changes the physiological absorption of vitamin D in the gastrointestinal tract.

The normal concentration of 25-hydroxyvitamine (Ergocalciferol and colecalciferol metabolites in the liver) in plasma ranges from 8-80 nanogam/ml. The concentration of less than 11 nanogam/ml is considered a deficiency of vitamin D in infants, breastfed and young children. Although the concentration is needed to maintain normal calcium metabolism and maintain the best bone mass in older children and middle -aged people who are unknown, but for the elderly may need to increase the amount of vitamin D put into the body to achieve the above goal.

Calcium absorption fraction varies with age, the highest in childhood (about 60%), decreasing to about 28%at puberty and increasing at the beginning of the puberty period (about 34%); The fraction of calcium absorption is 25% in young adults, and increases in the last 6 months of pregnancy. When the age is high, this fraction decreases, the average annual decline is about 0.21% in postmenopausal women; In men, the same decrease.

distribution:

about 40% of calcium in plasma binds to proteins, mainly albumin, about 1/10 forms a complex with anion (phosphate), the rest is a calcium in plasma in the form of physiological ionization. Calcium through the placenta and achieve concentration in fetal blood is higher than the mother's blood. Calcium is distributed into breast milk.

Vitamin D has a 19 to 25 hours of sale, blood circulation in combination with alpha-globulin, accumulated in the body for a long time.

transformation:

In Cholecalciferol liver, hydroxylation forms 25-hydroxycholeciferol. This substance continues to be hydroxylation in the kidneys to form a metabolism of 1.25 -dihydroxycholeciferol is active; This is a substance that increases calcium absorption. The non -metabolic part is stored in fat and muscle tissue.

excretion:

calcium excreted mainly on feces, including non -absorbing calcium, excreted through bile and pancreatic fluid into the gastrointestinal tract. A small part of calcium is excreted in the urine, a part of calcium is also eliminated through sweat. Armor hormones, vitamin D, thiazid diuretic reduces calcium secretion through urine, while other diuretics, calcitonin and growth hormone promote kidneys to excrete calcium. In healthy people, regular nutrition, calcium excretion through urine usually does not exceed 150 mg/day. Calcium excretion in urine decreases during pregnancy and in the early stages of renal failure, at high age.

Vitamin D mainly eliminated through bile and fertilizer, only a small amount of urine crabs.

Before taking Meyer Vita DC Memora Memora Treatment and Prevention of Vitamin D and Calcium deficiency, osteoporosis (20 packs)

How to use

Mixed nuggets, oral use.

Stir the medicine in a non -gas water glass until it becomes a mixture, drink immediately. Should be used before dinner.

Dosage

Adults and the elderly: Take 1 pack/day.

Patients with liver failure: No dose adjustment.

Patients with renal failure: The drug should not be used for patients with severe renal impairment.

Children: Do not use for children under 12 years of age because there is no clinical research data on safety and effectiveness.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

symptoms:

Taking overdose can lead to vitamin overdose and hypercalcemia. Symptoms of hypercalcemia include anorexia, thirst, nausea, vomiting, constipation, abdominal pain, muscle weakness, fatigue, mental disorders, dry mouth, multiple urinary, bone pain, calcium deposition in the kidneys, kidney stones and in severe cases causing arrhythmia. Excessive hypercalcemia can cause coma and death. Prolonged hypercalcemia can lead to non -recovery kidney damage and soft tissue calcification.

Management:

If hypercalcemia, the medication must be stopped. Stop treatment with thiazid, lithium, vitamin A and heart glycosides. Resuscitation, according to severity, isolation or treatment combined with diuretics, bisphosphonate, calcitonin and corticosteroids. The electrolyte in the serum, kidney function and the urinary tract must be monitored. In severe cases, it is necessary to monitor ECG (electrocardiogram), CVP (central venous pressure).

The toxic dose threshold of Vitamin D is 40,000 to 100,000 IU/day for 1-2 months in people with normal parathyroid function and calcium is over 2,000 mg/day. Symptoms of vitamin D poisoning are caused by hypercalcemia.

In case of emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double doses to compensate for missed dose.

Side Effects

When using Meyer Vita DC, you may experience unwanted effects (ADR) such as:

The frequency of ADR has not been determined. ADRs may occur:

Immune system disorders. skin.

urticaria.

Should avoid excessive treatment of blood calcium, because it turns into hypercalcemia is even more dangerous. Regularly determine serum calcium concentration, should be maintained at 9 - 10 mg/decadite (4.5 - 5 MEQ/liter). Serum calcium concentration usually does not exceed 11 mg/Decilide.

While treating with vitamin D, it is necessary to periodically measure calcium, phosphate, serum magnesium, blood urea nitrogen, alkaline alkaline phosphatase, calcium and phosphate in urine 24 hours.

Reducing phosphatase levels often appear before hypercalcemia in bone puree or kidney dysplasma.

Give plenty of water or infusion to increase the volume of urine, in order to avoid creating kidney stones in humans of urinary calcium.

Notify the physician the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Meyer Vita DC drug is contraindicated in the following cases:

Hypersensitivity to any ingredients of the drug.

Be cautious when using

need to be very careful when taking the drug for patients in the following cases:

Meyer Vita DC is used cautiously in patients with renal impairment or at risk of uroles. Blood calcium and calcium calcium levels should be monitored in these patients to prevent the onset of blood calcium hypercalcemia. Stop treatment if calcium concentration in urine exceeds 7.5 mmol/24 hours (300 mg/24 hours).

Use carefully for people with heart disease, patients who are taking glycosides aid, need to monitor serum calcium and electrocardiogram.

Other vitamin D compounds, derivatives, including foods containing vitamin D, can overdose vitamin D, should be avoided simultaneously with Meyer Vita DC.

Meyer Vita DC should be used carefully for patients with immune system disorders (sarcoidosis) due to the risk of increased vitamin D metabolism into activated form. These patients should be monitored in calcium levels in serum and urine.

The effect of the drug on the ability to drive and operate machines

Meyer Vita DC does not have or have a significant impact on the ability to drive and operate machinery.

Using drugs for women during pregnancy and lactation

Due to the high content of vitamin D, Meyer Vita DC is not indicated for use during pregnancy and lactation.

Pregnancy: Animal research shows that the overdose of vitamin D during pregnancy leads to teratogenic effects.

Breastfeeding period: Vitamin D and secretion of secretion into breast milk, Meyer Vita DC should not be used during breastfeeding.

Interactive drug

calcium reduces tetracyclin absorption. These two drugs should be used at least 3 hours away.

Some diuretics (Furosemid, Theracrynic Acid), antacids containing aluminum salts and thyroid hormones can inhibit calcium absorption and increase secretion in the kidneys and feces. Thiazid diuretics inhibit calcium excretion through the kidneys, causing increased blood calcium concentration.

Simultaneous treatment with cholestyramin, corticosteroids and mineral oils can reduce the absorption of vitamin D in the stomach, while phenytoin and barbiturates increase the conversion of vitamin D into non -active substances.

Increased calcium concentration increases the effect of inhibiting the enzyme Na - K - ATPASE of the heart glycoside, increasing the toxicity of the heart of the glycosides digitalis.

If using biphosphonate or sodium fluorid simultaneously with Meyer Vita DC, should drink at least two hours apart due to the absorption of the digestive tract of biphosphonate and sodium fluorid may decrease.

Foods containing phosphate, oxalic acid or phytinic acid can reduce calcium absorption.

Storage

Leave a cool place, avoid light, temperatures below 30⁰C.

To be out of reach of children, read the instructions carefully before use.

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