Meyerlapril 10 meyer - BPC supports the treatment of hypertension, heart failure (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Enalapril

Ingredient

Composition information	Content
Enalapril	10mg

Uses

indicated

meyerlapril 10 is indicated in case of:

Treatment of hypertension.

Treatment of heart failure. Angiotensin. After drinking, Enalapril Maleat is hydrolyzed into enalaprilate activity in the liver.

Enalapril reduces blood pressure by reducing the entire peripheral resistance with a slight increase or no increase in the heart frequency, systolic flow or cardiac flow. Medications that cause artery and veins.

In heart failure, Enalapril reduces money and post -load, cardiac weight can increase without significantly affecting the heart rate.

Long -term treatment with Enalapril reduces hypertrophy, symptoms and heart failure and increases stamina during exertion.

Pharmacokinetics

absorption

After drinking, about 60% of Enalapril dose is absorbed from the gastrointestinal tract and is not affected by food. The maximum concentration in plasma is achieved after drinking 4 hours and the hemodynamic effect lasts about 24 hours.

Elimination

The drug is discharged through the kidneys. When stopping the drug suddenly does not cause unexpected hypertension.

Before taking Meyerlapril 10 meyer - BPC supports the treatment of hypertension, heart failure (10 blisters x 10 tablets)

How to use

Meyerlapril 10 oral medication.

Dosage

Definitely hypertension

Adults: The starting dose of 2.5 - 5 mg/day. Adjust the dose by response to the patient's blood pressure. Maintenance dose: 10 - 20 mg, oral 1 time/day; normal dose limit 40 mg/day.

Simultaneous treatment with diuretics

Discontinue diuretics 1-3 days before treatment with transferred inhibitors and need to use the drug in very low -dose, 5 mg or less than 24 hours. Gradually increase the dose carefully according to the treatment response.

heart failure

usually combined with digitalis and diuretics, so the diuretics should be reduced before taking Enalapril and the patient must be carefully monitored. The starting dose is 2.5 mg gradually increasing to the maintenance dose.

kidney failure

Dose reduction and time between 2 drug use must be extended. For patients with severe renal impairment (clearing creatinine ≤ 30 ml/minute or serum creatinine ≥ 3 mg/dl), the starting dose is 2.5 mg. Daily dose should not exceed 40 mg.

In patients with peritoneal fertilizer, the usual dose is 2.5 mg.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Symptoms: Hypotension.

Handling: stop treatment with enalapril and monitor patients closely, apply symptomatic and supportive treatments such as vomiting, gastric lavage, plasma intravenous and sodium chloride 0.9% to maintain blood pressure and treat electrolyte imbalance. Hemorrhage can eliminate Analapril from circulation.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When experiencing side effects of the drug, patients need to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Common, ADR> 1/100

No report.

Uncommon, 1/1000

No report.

Not determined frequency

Nervous system: headache, dizziness, fatigue, insomnia, paresthesia, sensuality.

Digestive system: Intense disorders, diarrhea, nausea, vomiting, abdominal pain. Cardiovascular: angioedema, severe hypotension, hypotension posture, fainting, chest drum and chest pain. Respiratory: dry cough.

DA: rash.

Other: kidney failure.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

contraindicated

Meyerlapril 10 contraindicated drug in the following cases:

Sensitive to Enalapril.

There is a history of nerve edema due to enzyme inhibitors.

Renal artery stenosis on both sides or kidney artery stenosis only one kidney.

Aortic valve stenosis, and severe congested heart muscle disease.

Hypotension first.

Be cautious when using

with kidney function reductions.

For suspected kidney stenosis, blood creatinine requires before starting treatment.

The ability to drive and operate machinery

should not use drugs for drivers or operating machinery.

Pregnancy

should not be used for pregnant women.

breastfeeding period

enalapril excreted through breast milk. With the usual dose of treatment, the risk of harmful effects for breastfeeding is very low.

Drug interaction

contraindicated when coordinating

Diuretics, potassium benefits (spironolacton, triamteren, amiloride), plasma potassium concentration may increase, especially in the case of kidney failure, so regular testing of potassium concentration.

There are several facts that shows NSAIDs to reduce the effects of Enalapril.

Precautions when coordinating

Other drugs for hypertension (plus force), pay attention to the thiazide diuretics.

Lithium (decreased lithium clearance).

narcotic (increased lowering effect).

alcohol (alcoholic effect).

Other vasodilators (eg nitrate), anesthesia: may cause severe hypotension. In that case, the patient should be closely monitored and adjusted by increasing the volume of circulatory (infusion).

Storage

The temperature does not exceed 30 ° C, in a dry place, avoiding light.

Other drugs

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