Meyerursolic 300mg Meyer - BPC improves liver function, dissolves cholesterol stones (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Ursodeoxycholic acid

Ingredient

Composition information	Content
Ursodeoxycholic acid	300mg

Uses

indications

Meyerursolic medicine indicated in the following cases:

Improve liver function in primary bile cirrhosis or chronic liver disease c. Ursodeoxycholic acid inhibits the synthesis and secretion of cholesterol in the liver and inhibits the absorption of cholesterol in the intestine. The drug is used to dissolve cholesterol -rich stones in patients with gallbladder still active.

Dynamic pharmacokinetics

absorption: Ursodeoxycholic acid absorbs through the gastrointestinal tract after drinking and undergoing the liver - intestinal cycle.

Distribution: Ursodeoxycholic acid is partially combined in the liver before excreting bile.

Metabolism and elimination: Under the effects of intestinal bacteria, free-form and combined form undergo 7-α-dehydroxy process forming lithocholic acid, partly excreted in the fertilizer, the rest is absorbed, mainly conjugated and sulfate in the liver before eliminating fertilizer.

Before taking Meyerursolic 300mg Meyer - BPC improves liver function, dissolves cholesterol stones (3 blisters x 10 tablets)

How to use

oral medication.

Dosage

First biliary cirrhosis

Adults and the elderly: 10 - 15 mg/kg/day, divided into 2-4 times.

Children: Dosage calculated by body weight.

Melt cholesterol stones

Adults and the elderly: 6 - 12 mg/kg/day, divided into 2 times or take 1 single dose in the evening. Dosage can increase to 15 mg/kg/day in obese patients, if necessary.

Treatment time may last up to two years, depending on the size of the gravel, and should be continued three months after the gravel is dissolved.

Children: Dosage calculated by body weight.

Children with cystic fibrosis, from 6 years old to under 18 years old: 20 mg/kg/day divided into 2-3 times, increasing to 30 mg/kg/day if needed.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Symptoms: may have diarrhea. In general, other symptoms of overdose are almost none, because the absorption of ursodexolic acid decreases when the dose increases and thus are more excreted in the feces.

Management: Treatment of diarrhea symptoms combined with water and electrolyte balance. Ion exchange resin may be helpful to connect bile acids in the intestine. Encourage liver function test.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Meyerursolic drugs often have unwanted effects (ADR) such as:

digestive disorders:

Common (1/100

Very rare (ADR Ursodeoxycholic acid can cause nausea and vomiting (unknown frequency).

liver disorders:

Very rare (ADR

Skin and subcutaneous disorders:

Very rare (ADR

Ursodeoxycholic acid can cause itching (unknown frequency).

Notify the doctor the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Meyerursolic drugs in the following cases:

Hypersensitivity to any ingredients of the drug. Pregnancy and nursing women.

Caution when using

In the first 3 months of treatment, liver function parameters such as AST, ALT and Y-AG should be monitored every 4 weeks, then every 3 months.

In the case of treatment of cholesterol gallbladder stones, it is recommended to check the effectiveness of visual diagnosis after 6 months. If X-rays do not see gallbladder, gallstones with chemicals, gallbladder reduction or frequent pain of bile cramps, Meyerursolic is not used.

If diarrhea, dose reduction, in case of diarrhea remains, should stop the drug.

Avoid coordinating with liver toxic drugs.

The excipient of the drug contains lactose, should not be used for patients with galactose intolerance, lactase deficiency, glucose-galactose absorption disorders.

Be cautious with the ingredients of the color of the drug (Sunset Yellow, Tartrazin, Ponaceau) can cause allergic reactions.

Using drugs for women during pregnancy and lactation

Pregnancy: There is no adequate data on the use of ursodeoxycholic acid, especially in the first three months of pregnancy. Animal studies have shown the likelihood of monitoring in the early stages of pregnancy. Therefore, the drug is not used during pregnancy unless it is really necessary.

Breastfeeding period: There is no clinical data on the safety of ursodeoxycholic acid in breastfeeding women. Therefore, Meyerursolic is not recommended for this group of patients.

The effect of the drug on driving and operating machinery

The drug does not affect the ability to drive or operate machinery.

Drug interaction

should not be used simultaneously ursodeoxycholic acid with activated carbon, colestyramin, colestipol or antacids containing aluminum hydroxyd and/or smectit (aluminum oxide), because these products are associated with ursodexolic acid in the intestine as inhibiting the absorption and effectiveness of the drug. If it is necessary to use these drugs, take at least 2 hours before or after taking ursodexolic acid.

Ursodeoxycholic acid may increase the absorption of cyclosporin from the intestine. In patients who are treating cyclosporin, cyclosporin concentration should be checked and dose adjustment if necessary.

In some cases, ursodeoxycholic acid may reduce the absorption of ciprofloxacin.

Ursodeoxycholic acid has been shown to reduce the peak concentration in plasma (CMAX) and the area under the curve (AUC) of nitrendipine nitrendipine antagonistic calcium. An interaction that reduces the effectiveness of DASSON treatment has also been reported.

Oral contraceptives, estrogen hormones and medications that reduce blood cholesterol such as clofibroT may increase gallstones, the opposite of ursodeoxycholic acid used to dissolve gallstones.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.