Mg-Tan Inj 480ml infusion fluid provides water, electrolytes, amino acids and calories for patients

Dosage form Bag
Specifications Amino acids, glucose
Ingredient Mg CO., Ltd

Ingredient

Composition information	Content
Amino Acids	20%
Glucose	11%

Uses

Indications

Inj a mg-tan Inj infusion fluid provides water, electrolytes, amino acids and calories for patients by intravenous injection for patients who cannot be nutritious by gastrointestinal tract or nutrition by inappropriate gastrointestinal tract.

Pharmacokology

Glucose: The pharmacological effect of the infusion glucose is as necessary as the glucose provided by conventional foods.

amino acids and electrolytes: Pharmacological effects of amino acids and electrolytes are necessary like amino acids and electrolytes provided by conventional foods.

However, for amino acids through the path of eating, it will first pass through the blood vessel and then go into the circulatory system, while the amino acids through the infusion path goes directly into the circulatory system.

lipid: Lipid emulsion is a biological properties similar to endogenous fluids. Unlike conventional fluids, lipids do not contain cholesterol esters or apolipoproteins while phospholipid content is higher. Lipid emulsion epidemic metabolized during the cycle is like normal endogenous fluids during metabolism.

The endogenous lipid particles are mainly hydrolyzed during the circulatory process and are posted by peripheral and liver LDL receptors. The ability to metabolize is determined by the components of lipid particles, nutritional status, disease and transmission speed.

In healthy volunteers, the ratio of emulsion lipid metabolism after transmission is 3.8 + 1.5g triglyceride per kg of body weight within 24 hours.

The ability to metabolize and oxidation rate depends on the clinical conditions of each patient, faster metabolism and increased absorption for patients after surgery and trauma, while patients with renal impairment and hyperglyceride blood, the ability to absorb endogenous lipids slower.

Dynamic pharmacokinetics

glucose: Glucose provides and maintains normal nutritional state.

amino acids and electrolytes: amino acids are the components in the protein of pine foods, used to synthesize tissue proteins. If overdose will lead to elimination.

Research has shown the heating effect during amino acid transmission.

Lipid emulsion: Lipid emulsion provides saturated and unsaturated fatty acids essential for energy metabolism and the structural integrity of the cell membrane. Emulsion at the appropriate dose does not cause changes in blood sugar. There is no clinical proof that refers to changes in lung function when lipids are used an appropriate dose.

The increase in liver enzymes in some patients during the infusion process but will disappear when the infusion stops. The above change process is similar to some other types of infusion without lipid emulsion.

Before taking Mg-Tan Inj 480ml infusion fluid provides water, electrolytes, amino acids and calories for patients

How to use

mg-tan Inj can be used for central or peripheral intravenous infusion.

Dosage

Dosage and transmission speed should be determined accordingly for each specific patient based on the ability to metabolize fat, glucose metabolism, weight, clinical condition and nutritional requirements of the patient. Should choose the type of packaging with a capacity suitable for the dose level for each patient.

Mg-Tan Inj dose is recommended for adults as follows:

Patients with normal diet, not high energy demand: drip intravenous infusion at a dose of 0.7 ~ 1.0 g of total amino acid/kg weight/day (equivalent to 0.10 ~ 0.15 g of nitrogen/kg weight/day.

Patients with diets need a lot of energy: intravenous infusion at a dose of 1.0 ~ 2.0 g of total amino acid/kg weight/day (equivalent to 0.15 ~ 0.30 g of nitrogen/kg weight/day).

Normally, the dose of 0.7 ~ 1.0 g of total amino acid/kg weight/day or 0.10 ~ 0.15g nitrogen/kg weight/day of intravenous injection drip or peripheral corresponding to the dose of 27 ~ 40 ml of mg-tan inj/kg weight/day.

The injection speed must not exceed 3.7 ml/kg/hour (equivalent to 0.25g of glucose; 0.09g of amino acids and 0.13g of lipid/kg/hour), should be injected within 12 to 24 hours.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? When these symptoms appear, the drug transmission should be immediately considered for blood separator or peritoneal.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Mg-Tan Inj infusion, there may be unwanted effects such as increased body temperature (about 3% of patients taking drugs) or symptoms such as headache, nausea, vomiting, dizziness (less than 1% of patients taking drugs). There may also be other unwanted effects such as increased liver enzyme induction; thrombosis when infusion in the peripheral vein.

Some unwanted effects are very rare when using the drug, including: symptoms of anaphylaxis (urticaria, rashes, chills, chills, hypotension, cyanosis, shortness of breath) or fat syndrome with symptoms such as hyperlemia, fever, liver pain, liver pain, lag

Notify the physician the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Injgous infusion fluid in the following cases:

Hypersensitivity to eggs, soybean protein or allergic to any ingredients of the drug. Blood is using insulin within 6 hours. Increase the volume of intracellular fluid, water stasis, weakness; Damage to the heart. Progressive diabetes; acute myocardial infarction; metabolic acidosis; Severe blood infections; coma.

Be cautious when using

Precautions when using the drug in patients:

Patients with lipid specialized disorders; renal function; pancreatitis; liver function; Hypergian hyperpigmentation has increased blood triglycerides; Blood infection. Providing inadequate oxygen oxygen; dehydration.

General notes when taking the drug:

It is necessary to closely monitor clinically when starting to infect drugs to patients. When there is any abnormal signs, it is necessary to stop the infusion process immediately.

Before infusion, electrolyte test should be tested for patients to be able to specify the most appropriate dose.

To limit the risk of infection when injecting the tools must ensure aseptic, operations, procedures must be in accordance with the process.

Blood triglyceride concentration does not exceed 3 mmol/l within 5-6 hours after infusion.

Because the composition of the drug contains amino acids, it can increase micronutrients such as copper or zinc through the urinary tract, so it is necessary to consider adding micronutrients to patients who have to inject long -term drugs.

To limit the risk of the taboos as well as the risk of blood clotting, do not add other drugs to the infusion fluid and should not be injected with other drugs while injecting Mg-Tan Inj.

While taking the drug, it is necessary to closely monitor the concentration of blood glucose, electrolyte, osmotic pressure of blood; Acid - base balance, electrolyte balance and liver function (alkaline phosphatase, ALT, AST) of the body.

When taking the drug for a long time, the body's blood formula and blood recipes are needed.

When infusion of patients with renal function, it is necessary to closely monitor the level of phosphate and potassium to be supplemented to the patient to prevent the risk of alkaline infection or metabolic acidosis.

Need regularly for patients to test the electrolyte to adjust the dose accordingly.

Note when using:

Not used when the bag of the transmission bag has been broken. Amino acid and electrolyte solution (solution B) is not transparent or fat emulsion (C) is homogeneous.

The effect of the drug on driving and operating machinery

Mg-Tan Inj does not affect the ability to operate machinery and driving.

Using drugs for women during pregnancy and lactating

using drugs in pregnant women: should only be used if it is really necessary, based on the benefits of treatment and risks that may occur for the fetus.

Use drugs in nursing women: Be careful when using the drug in breastfeeding women.

Drug interaction

so far has not recorded clinical drug interactions, but there have been some reports on the following phenomena:

When used with insulin can affect the lipase enzyme.

Clinically

, heparin dose may increase temporarily due to increased amount of lipoprotein lipase. The temporary increase of plasma lipolysis in the initial stage when taking the drug is due to the deceleration of triglyceride clearance.

Because soybean oil contains vitamin K1, it can affect the effects of anticoagulants of Coumarin, so patients need to be monitored to use these drugs while being treated with Mg-Tan Inj.

tests of bilirubin, lactat dehydrogenase, saturated oxygen, hemoglobin, ... in blood samples taken tested during the mg-tan Inj infusion period may give inaccurate results due to lipid component. Most patients, blood samples taken after intravenous infusion for 5-6 hours do not affect the results of these tests.

Storage

Do not peel off the plastic bag. Store in closed boxes, at room temperature below 30 ° C. Do not freeze.

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