Mirzaten tablets 30mg Krka treat depression (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Mirtazapine

Ingredient

Composition information	Content
Mirtazapine	30mg

Uses

indications

Mirzaten 30 mg drug is indicated in the following case: Treatment of depression.

Pharmacokology

mirtazapin operates inhibiting receptors α2 money synap, increasing central neurotransmitter and serotonin transmission.

Dynamic pharmacokinetics

After drinking, the active ingredient Mirtazapin quickly absorbed (bioavailable ~ 50%), reaching the peak concentration in plasma after 2 hours. Food does not affect the pharmacokinetics of Mirtazapin. The link of mirtazapin with plasma proteins is about 85%. Mirtazapin is metabolized and eliminated through feces and urine within a few days. The sale time is 20 - 40 hours.

Before taking Mirzaten tablets 30mg Krka treat depression (3 blisters x 10 tablets)

How to use

Should drink mirzaten at the same time every day. It is best to drink before going to bed. However, the doctor may ask you to divide the dose of Mirzaten once in the morning and once and at night before going to bed. Higher doses should be taken before going to bed.

Swallow pills with water or juice, do not chew the medicine.

Dosage

Treatment of depression:

Adults: The normal starting dose is 15 or 30 mg per day. The dose may be increased after a few days to get the best dose (from 15 - 45 mg). The usual dose is the same with all ages. Used above is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when using overdose? The most common manifestation of Mirzaten overdose is drowsiness, loss of orientation and increased heart rate.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Mirzaten, you may experience unwanted effects (ADR).

Very common, common, ADR> 1/100

Mental: indifferent, increased appetite and weight gain, vivid dreams.

nerve: headache, drowsiness or drowsiness, dizziness, shaking or shudder, confusion, anxiety, difficulty sleeping. digestive: dry mouth, nausea, vomiting, diarrhea.

DA: DA.

musculoskeletal: muscle pain, joint pain, back pain.

Cardiovascular: Hypotension. Body: Fatigue, swelling.

Uncommon, rare, ADR

Mental: Feeling excited or highly emotional (manic), hallucinations, aggressive behavior.

nerve: restless legs, fainting, numbness in the mouth, nightmares, excitement, feeling of promoting movement, convulsions.

Hepatoma: jaundice, yellow eyes.

skin: abnormal skin, pain, itching or tingling, abnormalities.

Not determined frequency

Signs of infections such as a sudden high fever of unexplained cause, dry throat and mouth ulcer (granulocytosis).

Instructions on how to handle ADR

Patients stop using Mirzaten and notify the doctor immediately when there are any of the following signs: feeling excited or highly emotional (manic), signs of infection such as sudden high fever of unknown reasons, dry throat and mouth ulcers (leukemia), seizures (convulsions), jaundice and yellow eyes manifestation of liver dysfunction.

In addition, if there are many symptoms such as unexplained fever, sweating, increased heart rate, diarrhea, muscle spasm (uncontrolled), trembling, excessive reaction, restlessness, mood change and unconsciousness, this may be a sign of Serotonin syndrome, need to stop using Mirzaten and notify the doctor immediately.

If any unwanted effects become serious or you notice any unwanted effects not listed above, please notify your doctor or pharmacist.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindications:

Mirzaten 30mg contraindications in the following cases:

allergies to mirtazapin or any excipients of Mirzaten.

Patients who are taking or have just been used (in 2 weeks ago) Monoamine inhibitors Oxidase (Mao-IS).

Be cautious when using

Mirzaten usual should not be used with children and teenagers under 18 years of age due to not proven effectiveness, the drug can increase the risk of unwanted effects such as deliberate suicide, suicide thoughts and hostility (mainly aggressive, anti -opposition and anger). If the doctor prescribes Mirzaten for patients under 18 years old and you want to discuss that, please see your doctor again.

You should notify your doctor if any symptoms become worse or become worse for patients under 18 years old who are using Mirzaten.

If you've ever encountered the following conditions, tell your doctor before taking Mirzaten:

seizures or epilepsy progress more often. Stop taking the drug.

Heart or low blood pressure.

The ability to drive and operate machines

mirtazapin may affect your ability or alertness. Make sure these possibilities are not affected before you drive or operate machinery.

pregnancy

limited experiences in the treatment of mirzaten in pregnant women does not show increased risk. However, be careful if used during pregnancy.

The period of breastfeeding. There is no human data available.

Drug interactions

Do not use mirzaten simultaneously with: Monoamine oxidase inhibitors (Mao inhibitors).

Be careful when using Mirzaten with:

Antidepressants such as SSRIs, Venlafaxin and L-Tryptophan or Triptan, tramadol , Linezolide, Lithium and St. John Wort can lead to serotonin syndrome. Spirit like olanzapin, cetirizin allergies, painkillers like morphine can increase drowsiness. Warfarin.

Storage

Keep the medicine out of reach with children. Do not store drugs at temperatures above 30 ° C.

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Disclaimer

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