Momeex Nasal Spray Hanlim nasal spray is treated with seasonal rhinitis (18ml)

Dosage form Bottle x 18ml
Specifications Mometason Furoat

Ingredient

Thành phần cho 1ml

Composition information	Content
Mometason Furoat	0.5mg

Uses

Indications

Momeex Nasal Spray is indicated in the following cases:

Indications for adults, adolescents and children from 2 to 11 years old to treat seasonal or seasonal rhinitis symptoms. And related symptoms such as congestion and loss of odor ability in adult patients> 18 years old. Acute sinusitis.

In the study of the nasal antigen stimulant, Momeex shows anti -inflammatory effects in both early and late phase allergies, this is shown by the decrease phenomenon (compared to Placebo) Histamine and eosinatic activity, eosine, and decrease (compared to the original) eosinophilia, neutrophils and epithelial binding proteins.

pharmacokinetics

Mometason Furoat, when using nasal spray, there is negligible systemic bio -biology ( Clinical safety data:

Pre -clinical studies have shown that Mometason Furoat does not have the activity of androgenic, Anti - Androgenic, Estrogenic, and Anti - Estrogenic like other glucocorticoids, it has several anti -uterotrophic activity and hinder the vaginal opening in animal models when oral high doses of 56 mg/day/day and 280 mg/day

In cell culture, it has been shown that Mometason Furoat inhibits the release/synthesis of Il - 1, IL - 6 and TNFα fold at least 10 times compared to other steroids, including Beclomethasone Dipropionate, Betamethason, Hydrocortison and Dexamethasone. Mometason Furoat (IC50 = 0.12 Nm) Bamboo synthesized IL - 5 stronger than 6 times stronger than Beclomethason Dipropionate and Betamethason. In addition, in the mixture of white blood cells of allergies, Mometason inhibits Leukotrien synthesis stronger than Beclomethason Dipropionate.

Like other glucocorticoids, Mometason Furoat causes teratogenicity in rats and rabbits. In studies on teratogenicity, the drug also reduces the mother's body weight, affecting the development of the fetus (the fetal weight is lower or/and restricting bones) in rats, rabbits and rats and reducing the likelihood of survival in mice.

Before taking Momeex Nasal Spray Hanlim nasal spray is treated with seasonal rhinitis (18ml)

How to use

Momeex Nasal Spray is used to spray nasal spray.

After each Momeex Nasal Spray pump (usually 10 sprays until the gas spray is homogeneous, each spray releases about 50 mcg Morpetason Furoat. If you do not use a spray bottle for 14 days or longer than before the next use, each pump is pumped again (2 spray spray until you see a homogeneous spray solution).

Shake the spray bottle carefully before each use.

Instructions for use

Small nose to clean the nose. Shake the bottle gently and remove the dust lid.

Put the index and middle finger on the sides of the spray and thumb into the body of the bottle towards the spray nozzle and press the finger down to pump the spray.

cover one side of the nostril and put the nozzle into the other side as shown. Snight tilting his head forward, holding the bottle vertically. Start inhaling gently or slowly through the nose and while inhaling, spray by using your fingers definitely a spray.

Breathe out through the mouth. Repeat step 3 to inhale the implant spray for the same side of the nostril. Draw the spray from the nostrils and exhale through the mouth.

Repeat step 4 for the other nostrils.

After spraying, wipe the kidneys with a handkerchief or clean paper towel.

Close the dust -proof lid.

Spray cleaning

For effective spray, it is necessary to clean the spray regularly. Remove the dust -proof lid and push the spray. Wash the nozzle and dust -proof lid in warm water, then rinse under water. Dry in place warm. Insert the spray hose into the bottle and cover the dust -proof lid. Need pump bait when used for the first time after cleaning the spray bottle.

Dosage

Seasonal or year -round allergic rhinitis

Adults (succeeding for the elderly) and teenagers> 12 years old

The usual dose for prophylaxis and treatment is two sprays (50 mcg/spray) for each nose, 1 time/day (total dose of 200 mcg). Once the symptoms have been controlled, the dose is reduced to 1 spray for each nose (total dose of 100mcg) can effectively maintain.

If not controlled symptoms, it should be increased to the maximum daily dose of 4 sprays for each nose/day (total dose of 400 mcg). The dose should be reduced after symptoms.

The significant effect on the forest appears early after 12 hours of the first dose.

Children from 2 to 11 years old

The usual proposal is 1 spray (50 mcg/spray) for each side of the nose, 1 time/day (total dose of 100 mcg). Adults should help children when taking medicine.

Nose polyps

Adults (both elderly) and 18 -year -old teenagers usually in nasal polyps are 2 sprays (50 mcg/spray) for each nose, 2 times/day (total dose of 400 mcg). Once the symptoms have been controlled well, the dose should be reduced to 2 sprays for each side of the nose, 1 time/day (total dose of 200 mcg).

acute sinusitis

The usual proposal in acute sinusitis is 2 sprays (50 mcg/spray) for each side of the nose x 2 times/day (total dose of 400 mcg). Ask your doctor if the symptoms become worse during treatment.

Support treatment in acute sinusitis

Adults (next to the elderly) and minority> 12 years old

The usual dose is 2 sprays (50 mcg/spray) each side x 2 times/day (total dose of 400 mcg).

If not controlled good symptoms can increase up to 4 sprays (50 mcg/spray) for each side x 2 times/day (total dose of 800 mcg).

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Momeex Nasal Spray, you may experience unwanted effects (ADR).

Seasonal and year -round allergic rhinitis

Local side effects related to treatment are reported in clinical studies in adult patients and young people including headache (8%), nosebleeds (such as real bleeding, mucosal bleeding, and bleeding spots) (8%), nasal burning pharyngitis (2%), nose irritation (2%), and nose ulcers (1%), these extra effects see CORTCOSTEROODOIDOOIoid nose. Nosebleeds often go away on their own and from mild to severe, appearing at a higher rate than Placebo (5%) but at a ratio of or lower than the corticoseroids using the nose in the control study (up to 15%).

In children, the ratio of side effects such as headache (3%), nosebleeds (6%), nose stimulation (2%) and sneezing (2%) is similar to Placeboo.

Instant hypersensitivity reactions (such as bronchospasm, shortness of breath), but rarely, may appear after using Mometason Furoat nasal sugar. Very rarely report on anaphylactic and angioed reactions.

Very rare reports to change the taste and smell.

Nose polyps

In nasal polyps, the ratio of gums appear is similar to placo and similar to the side effects of observation with allergic rhinitis.

acute sinusitis

In patients with acute sinusitis, in general, the ratio of the appearance of gums is similar to the Placebo and similar to the side effects of observation with allergic rhinitis.

Support treatment in sinusitis waiting for acute sinusitis

In adults and adolescents using Momeex Nasal Spray such as supportive treatment during acute sinusitis, side effects related to treatment, appearing in the same proportions as Placebo, including headache (2%), pharyngitis (1%), nose burning (1%) and nose stimulation (1%). Mild to severe nosebleeds and also appears with the comparison ratio with Placebo (5% compared to 4%).

Instructions on how to handle ADR

Notice the doctor the effects of the desire to encounter when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Momeex Nasal Spray is contraindicated in the following cases:

Hypersensitivity to any ingredients of the drug.

Caution when using

should not use Momeex Nasal Spray when there is a localized infection in the nasal mucosa.

Due to the corticosteroids inhibiting wound healing process, nasal corticosteroids do not use nasal surgery patients or trauma until wound healing.

After 12 months of treatment with Momex Nasal Spray, there is no evidence of nasal mucosa; In addition, Mometason Furoat tends to restore the nasal mucosa back to normal phenomenon. Like any other scissors treatment, patients using Momeex Nasal Spray lasted for months, so they were checked for periodic changes that may appear in the nasal mucosa. If the fungal infection is localized in the nose or pharyngeal, stop using Momeex Nasal Spray or may need appropriate treatment. Stimulating in the nose - prolonged pharynx can be an indication to stop using Momeex Nasal Spray.

Should use Momeex Nasay Spray in patients with dynamic tuberculosis or respiratory mute, or fungal infection, bacterial infection, unexplained body virus infection or herpes simplex herpes.

There is no evidence to inhibit the hypothalamus - pituitary - adrenal gland (HPA) after prolonged treatment with Momeex Nasal Spray. However, careful monitoring of patients specialized from using corticosteroid strip to body effect to Momeex Nasal Spray. Stop using whole corticosteroids in these patients can cause adrenal insufficiency for months until the HPA shaft function recovers. Systemic corticosteroids should be reused if the patient shows signs of adrenal inhibition and should apply other appropriate treatments.

In a reference clinical study, there is no observation that reduces growth in children using Momeex Nasal Spray 100 mcg/day for 1 year.

Not safe and effective research of Momeex Nasal Spray in the treatment of nasal polyps in children and young people under 18 years old.

During the transition from whole corticosteroids to Momeex Nasal Spray, some patients may manifest the symptoms of stopping the systemic corticosteroid (such as joint pain and/or muscle, fatigue and depression in the first stage) despite the decrease in the symptoms in the nose and still need to use Momeex Nasal Spray. This stage of conversion may appear existing allergies, such as allergic and eczema, which was previously covered by systemic corticosteroid treatment.

Patients who use strong corticosteroids inhibit immunosuppression should be warned when exposed to an infection role (such as chicken pox, measles) and the importance of medical examination if exposed to the infection.

Very rare reporting or increased intraocular pressure after using corticosteroid spray inside the nose.

Patients should see a doctor immediately show signs or symptoms of severe infections (such as fever, pain and toughness on one side/ tooth or swelling of the face, eye or peripheral eye, or symptoms that worsen after a period of improvement).

Not yet established the safety and effectiveness of Momeex Nasal Spray in the treatment of sinusitis symptoms in children under 12 years old.

The ability to drive and operate machinery

Using Momeex Nasal Spray does not affect the ability to drive and operate machinery.

Pregnancy

There is no appropriate research or good control in pregnant women. After inhaling the maximum proposal on the forest, the plasma is not quantified mometason concentration; Therefore, the concentration of Mometason in the embryo is negligible and very little toxicity for fertility.

As well as other corticosteroids use, Momeex Nasal Spray should be used for pregnant women, when the benefits of treatment outstanding risk for mothers and embryos. The children of mothers use corticosteroids during pregnancy should be carefully monitored the adrenal insufficiency.

Breastfeeding period

as well as other corticosteroids using nasal sugars, should use Momeex Nasal Spray for breastfeeding women or at birth when the benefits of treatment are at risk of mother and child emulsion.

Drug interaction

Momex Nasal Spray used in combination with Loratadin does not affect the plasma concentration of loratadin and its main metabolites. Mometason Furoist concentration is not predicted. Combined treatment is well tolerated.

Storage

Store in closed packaging, at temperatures not more than 30 ° C, avoid light.

To be out of reach of children.

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