Montiget nuggets 4mg Getz treat asthma in children (14 packs)

Dosage form 14 package box
Specifications Montelukast

Ingredient

Composition information	Content
Montelukast	4mg

Uses

indications

Montiget 4mg drug is indicated in the following cases:

Montiget Children (Montelukast) is assigned to treat children from 06 months and older in preventing and treating chronic asthma, including preventing day and night symptoms, treating patients with asthma due to abpirin sensitivity. Age and older to reduce the symptoms of seasonal allergic rhinitis and in adults and children aged 06 months and older to reduce allergic rhinitis all year round.) drink. Cysteinyl Leukotrienes (including LTC4, LTD4, LTE4) are metabolic products of arachidonic acid released from different cells including mast cells and eosinophilia. These eicosanoids are associated with cysteinyl leukotriene receptors (CYSLT).

The cohesion of cysteinyl leukotrienes on Leukotrienes receptor related to the pathophysiology of asthma, including gas edema, smooth muscle spasms, and cell activity in combination with inflammatory process, factors that lead to asthma symptoms. Therefore, Montelukast inhibits the physiological effects of LTD4 at CYSLT1 receptors and has no operational activity.

Pharmacokinetics

absorption

Sodium Montelukast is quickly absorbed by oral. The peak concentration of plasma of the drug is achieved after 2 to 4 hours of taking the drug. The average use of oral use is 64%.

Distribution

Sodium Montelukast is connected to blood protein at the rate of over 99%.

The average disposal time of the drug ranges from 2.7 to 5.5 hours in healthy adults. Dynamic pharmacokinetics of sodium montelukast almost linear when used orally at a dose of up to 50mg.

Metabolism

Sodium Montelukast is widely metabolized by the liver by iszymes cytochrome P450 CYP3A4, CYP2A6 and CYP2C9.

The therapeutic concentration of sodium montelukast in plasma does not inhibit cytochrome P450 3A4, 2C9, 1A2, 2A6, 2C19 or 2D6.

Elimination

The average clearance of sodium montelukast is 45ml/min in healthy people.

Sodium Montelukast and its metabolites are excreted mainly through feces and bile.

Before taking Montiget nuggets 4mg Getz treat asthma in children (14 packs)

How to use

Montiget nuggets can be used by putting nuggets directly into the mouth or mixing the drug with a spoon of cold food. Should only open the package right before use. Should take the drug for 15 minutes after the package is opened.

The drug should be used immediately after mixing with food, should remove the excess medicine. Do not use nuggets of nuggets by dissolving with drinking water, however, can drink drinking water after use. Can drink nuggets Montiget during and outside meals.

Dosage

Should use Montelukast 1 time/day. In the treatment of asthma, should take medicine at night. For seasonal allergic rhinitis, the time to take the drug depends on the needs of each patient.

Children from 2 to 5 years old with asthma or seasonal allergic rhinitis: Drink 1 pack of 4mg Montelukast/day.

Children from 6 months to 2 years of age with asthma or allergic rhinitis all year round 1 pack 4mg Montelukast/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Symptoms

The most common reactions are similar to the data of the safety of the drug including abdominal pain, drowsiness, thirst, headache, vomiting and agitation.

Treatment

There is no specific information to treat Montelukast overdose. In case of overdose, supportive measures such as non -absorbing removal, clinical monitoring, supportive treatment requirements. It is unclear whether Montelukast can be separated through peritoneal or dialysis.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Montiget 4mg, you may experience unwanted effects (ADR).

Montelukast is generally well tolerated. However, the following side effects are also recorded, usually occurring at a mild level and not necessarily stopping the drug:

Hypersensitivity reactions (including angioedema, rash, itching, urticaria and when liver leukemia occurs).

nightmares, hallucinations, chest drums, chicken sleep, hot -tempered, restless, insomnia, increased sweating, headache.

Nausea, vomiting, indigestion, diarrhea, abdominal pain.

Muscle pain, cramps.

Increase the trend of bleeding, purple edema.

Run, dry mouth, dizziness, joint pain.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Montiget 4mg drug is contraindicated in the following cases:

Montelukast is contraindicated in patients with hypersensitivity to drugs or any ingredients of the drug.

Montelukast is not indicated in acute asthma and asthma.

Be cautious when using

should not use Montelukast to suddenly replace oral or inhaled corticosteroids. However, the inhaled dosage can be reduced slowly.

Although the random relationship has not been established with Leukotriene receptor countertops, it is necessary to pay attention to check when reducing systemic corticosteroids in patients using Montelukast.

Do not use Montelukast single to treat asthma asthma. Patients with severe asthma after exertion should continue to use conventional treatments, which are inhaled lines to prevent and prepare drugs to prevent when used.

For cases of asthma caused by aspirin and nonsteroidal anti -inflammatory drugs, it is best to continue to avoid aspirin and nonsteroidal anti -inflammatory agents.

Be careful when using sodium montelukast to relax bronchi. When clinical response, need to reduce treatment.

The ability to drive and operate machinery

Montelukast has no effect on the ability to drive and operate machinery. However, in very few cases, the drug can cause drowsiness.

Pregnancy

Montelukast has not been studied in pregnant women. Should only be used for pregnant women if really necessary.

The period of breastfeeding

is not sure if Montelukast is excreted through breast milk. Because many drugs have the ability to excrete in milk, it is necessary to be cautious when using Montelukast for breastfeeding women.

Drug interaction

need to monitor clinical, especially in children, when using Montelukast with strong liver -induction substances such as phenyltoin, phenobarbital ... These can reduce acting under the curve (AUC) of Montelukast. It is not necessary to adjust the dose of Montelukast.

Storage

Store at temperatures below 30 ° C, avoid sunlight and humidity.

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