Mosane Tablet 5mg Arlico tablets treat gastroesophageal reflux disease, heartburn (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Mosaprid citrate

Ingredient

Composition information	Content
Mosaprid citrate	5mg

Uses

Indications

Mosane Tablet is indicated in the following cases:

Gastroesophageal reflux disease;

pharmacokinetic

absorption

In a human study, the maximum concentration achieved after 0.8 ± 0.1 hours of giving the drug, after taking the single dose citrate mosaprid, the maximum concentration of the drug in plasma is 30.7 ± 2.7 (ng/mL).

Distribution

Plasma protein bonding ratio is 99.0%.

Metabolism

Mosaprid Citrate metabolizes mainly through the liver, along with the main metabolic compound is Des-4-Fluorobenzyl.

Elimination

Sell waste time is 2.0 ± 0.2 hours.

Mosaprid Citrate is excreted mainly in urine and feces. After 48 hours of drinking 5mg of mosprid citrate, 0.1% of the urine component is excreted in the form of constant compound and 7.0% is excreted in the form of the main metabolite (DES-4-Fluorobenzyl compound).

Before taking Mosane Tablet 5mg Arlico tablets treat gastroesophageal reflux disease, heartburn (10 blisters x 10 tablets)

How to use

oral medication. Time to use the drug can be before or after meals.

Dosage

A dose of drugs 5 mg/time and 3 times/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Handling: Gastrointestinal lavage, active carbon and clinical monitoring. The drug is highly connected to plasma proteins, so it cannot be removed by a cup.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose of the recommended therapy. Do not double the dose to compensate for the forgotten dose.

Side Effects

When using Mosane Tablet, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: diarrhea, loose stool.

Hematology: Incretion of eosinophilia, increased triglycerides.

Uncommon, 1/1000

Digestive: dry mouth, burp.

Metabolic: Increase AST (GOT), ALT (GPT), ALP and Gamma-AGP.

Not determined frequency

Hypersensitivity: edema, rash, urticaria.

Hematology: Incretion, leukopenia. stomach - intestines: diarrhea, loose stools, dry mouth, abdominal pain, nausea, vomiting, changing taste, abdominal distention ...

Cardiovascular system: Brushing chest drums.

Nervous system: dizziness, headache.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Mosane Tablet drugs against patients with a history of hypersensitivity to Mosaprid or any ingredients of the drug.

Precautions when using

If no improvement in gastric - intestinal symptoms after a period of medication (usually 2 weeks) should be stopped.

Used in the elderly: Because the physiological function of the kidneys and liver is often impaired in elderly people, so be careful when using the drug by monitoring the patient's condition. If there is any side effect, it is advisable to apply appropriate measures such as reducing the dose.

Use in children: The safety of this drug in children has not been proven.

The ability to drive and operate machinery

Some side effects of the drug can be stunned, headache. Therefore, be careful when using mosaprid citrate when driving and operating machinery.

Pregnancy

There is no enough documents to prove the safety when using Mosaprid Citrate for pregnant women. Therefore, only use the drug when really necessary and need to consider the risk benefits before using the drug.

Breastfeeding period

There is no enough documents to prove the safety when using mosaprid citrate for nursing women. Therefore, only use the drug when really necessary and need to consider the risk benefits before using the drug. In case women are breastfeeding, if it is necessary to use the drug, it is necessary to stop breastfeeding during treatment with mosaprid citrate.

Medicinal interaction

When using the same dose of 1200 mg of erythromycin/day along with a dose of 15 mg of mosaprid/day instead of using this drug, the highest mosaprid concentration in the blood increases from 42.1 ng/ml to 65.7 ng/ml. The half -life lasts from 1.6 hours to 2.4 hours and AUC0 - 4 increases from 62 ng. Annes/ml to 114 ng.He/ml.

Mosaprid reduces the effects of anti -cholinergic drugs - Atropin Sulfate and Butyl - Scopolamin Bromid.

Storage

Storage in closed packaging, avoid moisture, light, at temperatures below 30 ° C.

Korea Arlico Pharm Co., Ltd established in 1995 in Korea. Arlico is researching and making efforts in all their business areas for public health and happiness. The ultimate goal of Arlico is to find a way to make the world a better place.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.