Motarute Daewoo Pharm eye drops treat conjunctivitis (5ml)

Dosage form Bottle x 5ml
Specifications Moxifloxacin

Ingredient

Composition information	Content
Moxifloxacin	5mg

Uses

Indications

Motarute eye drops indicate the treatment of conjunctivitis caused by bacterial strains sensitive to moxifloxacin.

Pharmacokology

moxifloxacin, is the fourth -generation Fluoroquinolon antibiotic, inhibiting DNA enzyme Gyrase and Topoisomerase IV necessary for duplication, repair and recombinant DNA.

sensitive bacteria strains

Aerobic Gram -positive bacteria

corynebacterium sp. include:

corynebacterium diphtheriae;

Staphylococcus aureus (Methicillin sensitive);

Aerobic gram bacteria

enterobacter clacae;

Haemophilus Influenzae;

proprionibacterium acnes.

Other bacteria

chlamydia trachomatis. Moxifloxacin plasma concentrations are measured in 21 men and women using eye drops for both eyes 3 times/day for 4 days. The average concentration in stable state CMAX and AUC is 2.7 ng/ml and 41.9 ng hours/ml respectively. These values are about 1600 times lower and 1200 times compared to CMAX and AUC when taking moxifloxacin 400 mg/day. Moxifloxin's semi -cancellation time is estimated at 13 hours.

Before taking Motarute Daewoo Pharm eye drops treat conjunctivitis (5ml)

How to use

eye drops.

Dosage

recommended dose: Put one drop into the eye 3 times/day.

Infections often improve within 5 days and should continue to take the drug for another 2-3 days. If the condition is not improved within 5 days, it is advisable to re -evaluate diagnosis and/or treatment. The treatment time depends on the severity of the disease and the clinical situation.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?
What to do if you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that double dose should not be used.

Side Effects

The following unwanted effects are considered to be related to treatment and are classified as follows: Very common (≥ 1/10), common (≥ 1/100 to Blood disorders and lymphatic systems:

Not common: reducing hemoglobin.

Nervous system disorders:

Common: rebellion.

Not common: headache, paresthesia.

Eye disorders:

Common: eye pain, eye irritation, dry eyes, eye itching, conjunctiva, congestion.

Unserved: Eye disabled before cornea, corneal spot, corneal dyeing, conjunctiva hemorrhage, conjunctivitis, eye swelling, discomfort in the eyes, blurred vision, vision loss, eyelid disorders, red eyelid disorders, abnormal sensation in the eyes.

Respiratory disorders, chest and mediastinum:

Not common: discomfort in the nose, laryngeal sore throat, feeling of strange objects in the throat.

Gastrointestinal disorders:

Not common: vomiting.

Liver disorders:

Not common: increasing alanin aminotransferase, gamma-glutamyltransferase.

Notify the doctor with unwanted effects related to the use of the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Motarute eye drops contraindicated in the following cases:

Hypersensitivity to active ingredients, with any excipients, or with other Quinolon antibiotics.

Precautions when used

In patients with systemic quinolon, there has been a report on serious hypersensitivity reactions (anaphylaxis) sometimes fatal, some cases after the first dose. A few reactions followed by cardiovascular collapse, loss of consciousness, angioedema (including pharynx, throat or facial edema), trachea obstruction, shortness of breath, urticaria, and itching.

If an allergic reaction to moxifloxacin occurs, stop taking the drug. When there is a serious hypersensitivity reaction due to moxifloxacin or any ingredient of the drug, need emergency treatment. Oxygen and ventilation should be used when clinical indications.

Like other antibiotics, long -term use can cause superinfection of non -sensitive bacteria including fungi. If superinfection occurs, stop taking drugs and apply alternative treatment.

There are very little data on moxifloxacin effectiveness and safety in the treatment of conjunctivitis in infants. Therefore, it is recommended not to use this drug to treat conjunctivitis in infants.

Do not use moxifloxacin treatment or prevent conjunctivitis caused by gonorrhea, including eye disease in newborns due to gonorrhea, caused by Neisseria Gonorrhoeae bacteria resistant to fluoroquinolon antibiotics. Patients with eye infections by Neisseria Gonorrhoeae should take appropriate systemic medication.

It is not recommended to use this medication to treat Chlamydia trachomatis infection for patients under 2 years old because there is no evaluation in these patients. Patients over 2 years of age with eye infections due to Chlamydia Trachomitis should take appropriate systemic medication.

Babies with eye disease should be treated appropriately, for example, using systemic medication in cases of chamydia trachomitis or neisseria gonorrhoeae.

It is recommended that patients should not use contact glass if there are signs and symptoms of eye infections.

Use drugs for women during pregnancy and lactation

Pregnant women

There is no sufficient data on the use of moxifloxacin in pregnant women. However, it can be predicted that the drug does not affect the fetus because the amount of moxifloxacin into the body is negligible. This drug can be used during pregnancy.

breastfeeding women

It is unknown whether moxifloxacin is excreted in breast milk or not. Animal studies show low secretion of milk when taking moxifloxacin. However, it can be predicted that in the treatment dose, moxifloxacin does not affect breastfeeding. This drug can be used in breastfeeding women.

affects the ability to drive and operate machinery

as well as all other eye drops, temporary blurred vision or visual disorders that can affect driving or operating machinery. If you get blurred when the drug is faded, the patient should wait until the eyes are visible clearly before driving or operating machines.

Medicinal interaction

Medicinal interaction may affect the activity of the drug or cause side effects.

Patients should notify the doctor or pharmacist a list of the drugs and functional foods you are using. Do not use or increase or decrease the dose of the drug without the guidance of a doctor.

Storage

Store less than 30ºC, avoid light.

Other drugs

Disclaimer

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