Moxieye eye drops 50mg treat eye infections, corneal ulcer (10ml)

Dosage form Jar
Specifications Moxifloxacin
Ingredient CPC1 Pharmaceutical Joint Stock Company Hanoi - Vietnam

Ingredient

Thành phần cho 10ml

Composition information	Content
Moxifloxacin	50mg

Uses

indications

Moxiye small eye solution is used to treat eye infections due to sensitive microorganisms; Treatment of corneal ulcer; Prevention of inflammation and infection may occur after eye surgery.

Pharmacokic

The mechanism of action of moxifloxacin is related to the inhibition of tosoisomerase IV enzyme and DNA gyrase. These enzymes need regeneration, copy, repair and combine the DNA of bacteria. In Gram (-) bacteria, fluoroquinolon works mainly on DNA gyrase rather than tosoisomerase IV, while in Gram (+) bacteria, the opposite.

moxifloxacin works with most strains of bacteria after both in vitro and in clinical infections:

Aerobic gram -positive microorganisms:

corynebacterium species

microbacterium species

micrococcus luteus (including anti -bacterial strains of erythromycin, gentamicin, tetracyclin and/or trimethoprim)

Staphylococcus aureus (including strains of bacteria against methicillin, erythromycin, gentamicin, ofloxacin, tetracyclin and/or trimethoprim).

Staphylococcus epidermidis (including strains of bacteria against methicillin, erythromycin, gentamicin, ofloxacin, tetracyclin and/or trimethoprim)

Staphylococcus Haemolyticus (including strains of bacteria resisting methicillin, erythromycin, gentamicin, ofloxacin, tetracyclin and/or trimethoprim)

Staphylococcus hominis (including methicillin, erythromycin, gentamicin, ofloxacin, tetracyclin and/or trimethoprim).

Staphylococcus Warneri* (including anti -bacterial strains of erythromycin)

Streptococcus pneumoniae (including strains of resistance to penicillin, erythromycin, tetracycline and/or trimethoprim)

Streptococcus Viridans Group (including strains of resistance to penicillin, erythromycin, tetracycline and/or trimethoprim)

Aerobic gram -negative bacteria:

Acinetobacter Species*

Haemophilus Aleonae (including ampicillin resistance strains)

Haemophilus Influenzae (including ampicillin resistance strains)

haemophilus parainfluenzae*

klebsialla pneumoniae

Moraxella catrhalis

pseudomonas aeruginosa

Other microorganisms: chlamydia trachomatis.

* Effective on this microorganism is studied less than 10 infections.

Dynamic pharmacokinetics

Moxifloxacin plasma concentrations have been measured in adults, both men and women, small eye moxifloxacin solution 0.5% 3 times daily. The average CMAX peak value in equilibrium (2.7ng/ml) and the daily absorption level of AUC (45NG.H/mL) lower than 1600 and 1000 times CMAX and AUC obtained after taking Moxifloxacin with a dose of 400 mg. Moxifloxacin plasma sale time is estimated at 13 hours.

Before taking Moxieye eye drops 50mg treat eye infections, corneal ulcer (10ml)

How to use

Moxieye small eye solutions are only used for eye drops.

Dosage

used in adults, including the elderly: 1 drop in the eyes is inflamed 3 times/day, taking drugs for 7 days.

Inflammation is usually improved after 5 days, it is necessary to continue treatment for 2 -3 days. If inflammation does not improve after 5 days of treatment, the doctor should consult.

Use in children: No need to adjust the dose. Safety and effectiveness of small eye solution with moxifloxacin in children under 1 year of age has not been determined.

Used in people with liver and kidney failure: No dose adjustment.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when overdose? Information about overdose is still limited. When the eye is overdose, the moxieye solution can be washed immediately with warm water to remove.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Moxiye drugs often experience unwanted effects (ADR) such as:

may experience conjunctivitis, hypotension, dry eyes, keratitis, discomfort in the eyes, erection, eye pain, itchy eye, bloody bleeding. These reactions occur in approximately 1 - 6% of patients.

Other unwanted effects that do not take place in the eye have been reported at a ratio of 1 - 4% such as fever, cough, bacterial infection, otitis media, pharyngitis, redness and rhinitis.

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Moxiye drugs contraindicated in the following cases:

You must not use Moxiye eye solution if you are allergic to any ingredients of the drug, with a history of hypersensitivity to moxifloxacin, quinolon.

Be cautious when used

as with other anti -infections, prolonged medication can lead to excessive development of sensitive microorganisms, including fungal superinfection. If superinfection occurs, it is necessary to see a doctor and apply appropriate treatment. If you are allergic to other antibiotics similar to moxifloxacin, you may be allergic to moxieye eye solution. In this case, you need to stop using the drug, see a doctor for appropriate treatment.

Use drugs in pediatrics:

Safety and effectiveness of moxieye solution in children under 1 year of age has not been determined.

There is no evidence that Moxiye eye drops are acting on bearing joints, although some quinolones are used by oral, indicating that causing joint diseases in adult animals.

Use drugs in aging:

There is no overall difference in safety and effectiveness that have been observed between older and young patients.

The effect of the drug on the ability to drive and operate machinery

is the same as when the eye is small, temporarily blurred and visual disorders can affect your ability to drive and control your machines. If you are blurred after the drug, you have to wait until you can see it clearly and control the machine.

Use drugs for women during pregnancy and lactation

Pregnant women:

Because there are no control and adequate studies in pregnant women, moxifloxacin solution should only be used during pregnancy when the benefits are higher than the risk that may occur for the fetus.

breastfeeding women:

moxifloxacin is not determined in breast milk, although moxifloxacin is thought to be excreted through breast milk. So kidneys while using moxieye solution during breastfeeding.

Drug interaction

There has been no study on drug interaction of eye small solution containing moxifloxacin. In vitro studies show that moxifloxacin does not inhibit CYP3A4, CYP2D6, CYP2C9, CYP2C19 or CYP1A2 so the drug is less likely to affect the pharmacokinetics of metabolic drugs by Cytochrom P450.

Storage

In a dry place, avoid light, temperature below 30 ° C.

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