Mucosta Tablets 100mg Otsuka tablets treat stomach ulcers, gastric mucosa (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Rebamipide

Ingredient

Composition information	Content
Rebamipide	100mg

Uses

Indications

Mucosta 100mg drug is indicated in the following cases:

Treatment stomach ulcer . Thickness, increased prostaglandin, protecting stomach cells, increasing mucus, increasing blood flow into the mucosa, acting on the mucosal fence, acting on the secretion of the stomach, acting on oxygen roots, effect on inflammatory cell contamination in the stomach mucosa, effect on cytokine release (Interleukin - 8) causing inflammation in the stomach mucosa.

pharmacokinetic

absorption

The absorption speed of Rebamipide after eating slower than before eating when taken oral at the dose of 150 mg. However, food does not affect the bioavailability of the drug in humans.

Distribution

98.4 - 98.6% of the drug is associated with plasma proteins.

Metabolism

Rebamipide is mainly excreted in urine in the form of constant drugs. A metabolic substance with a hydroxyl group in the 8th position has been found in the urine. However, the excretion of this metabolite is only 0.03% of the dose used. The enzyme related to this metabolic formation is Cytochrome P450 CYP3A4.

Elimination

10% of the dose is eliminated in the urine.

Before taking Mucosta Tablets 100mg Otsuka tablets treat stomach ulcers, gastric mucosa (10 blisters x 10 tablets)

How to use

Mucosta 100mg medicine is taken orally.

Dosage

Stomach ulcer

The dose of Rebamipide is usually used for adults is 100 mg (1 Mucosta 100 mg) 3 times/day in the morning, evening and before going to bed.

Treatment of gastric mucosa lesions in acute gastritis and exacerbations of chronic gastritis

The dose of Rebamipide commonly used for adults is 100 mg (1 mucosta tablet 100 mg) 3 times/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose? Symptomatic treatment should be treated.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Mucosta 100mg , you may experience unwanted effects (ADR).

Rare, 1/10000

Hematology: leukopenia, granulocytosis.

Liver: Increased concentration of AST, ALT, GGT, Alkaline Phosphatase.

Hypersensitivity: rash, itching, eczema is like a rash due to drugs, other sensitive symptoms.

Neurological - Mental: numb, dizziness, drowsiness, taste disorder .

Stomach - intestines: constipation, abdominal feelings, diarrhea , nausea, vomiting, heartburn, abdominal pain, belching, abnormal taste.

Menstrual disorders .

Increase blood urea nitrogen level (bun).

edema, the feeling of strange objects in the throat.

Not determined frequency

Hypersensitivity: Floating , shock and anaphylactic reaction.

Stomach - intestines: dry mouth , bloating.

jaundice.

Hematology: platelet reduction.

Swelling and pain, milk secretions due to large breasts in men, hair loss.

Brushing chest drums.

Fever, blushing, face.

Tongue numbness, cough, acute respiratory failure .

Instructions on how to handle ADR

Notify the doctor with unwanted effects when using the drug.

If there are symptoms of hypersensitivity, stop taking the drug.

If the transaminase level increases significantly or has, fever and rash, the medication must be stopped and taken appropriate treatment measures.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Mucosta medicine 100mg Contraindicated in the following case:

Patients with a history of hypersensitivity to any ingredients of the drug.

Precautions when using

used for the elderly

It is necessary to pay special attention to elderly patients to minimize the risk of stomach - intestines because of physiological, elderly patients are often more sensitive to this drug than young patients.

Use for children

Not yet determined the safety of this drug in mild birth weight, newborns, breastfeeding and children (not clinical experienced enough).

Do not swallow any part of the compressed blister (PTP). .

The ability to drive and operate machinery

There has been no studies that have been controlled on the effects of the drug when driving. A number of patients have been recorded dizziness or drowsiness while taking the drug. Such patients need to be cautious when driving or operating machinery.

Pregnancy

drugs should only be used for pregnant women or likely to be pregnant if the benefit of treatment is higher than any possible risk.

Breastfeeding period

Stop breastfeeding before using Rebamipide.

Drug interaction

No drug interactions have been recorded.

Storage

Storage below 30 ° C.

Other drugs

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