Naciti 500mg Nghe An Pharma tablets treat serious brain damage (3 blisters x 10 tablets)
Dosage form Box of 3 blisters x 10 tablets
Specifications Citicoline
Ingredient
| Composition information | Content |
| Citicoline | 500mg |
Uses
indications
Naciti drugs are indicated in the following cases:
ATC code: N06bx06.
Citicolin activates the phospholipid structure of the nerve cell membrane, increasing the metabolism in the brain, increasing the levels of many different neurotransmitters including acetylcholine and dopamine.
citicolin shows nerve protection effects in cases of lack of oxygen and anemia as well as improving manifestations of the ability to memorize and learn in brain aging.
citicolin, through the activity, improves the function of the meninges mechanisms such as the exchange of ion channels and channel receptors in which the regulation is necessary for an accurate neurotransmitter.
citicolin has anti -brain edema properties due to its stable activity on the nerve cell membrane.
Clinical trials show that citicolin improves symptoms that come with brain dysfunctions that occur after various processes such as brain injury and stroke. Citicolin improves cognitive and memory level, sensory disorders and movement with the above status.
pharmacokinetics
citicolin is a water -soluble compound with more than 90%bioavailability. Mobile pharmacokinetic studies on healthy volunteers show that citicolin doses are absorbed quickly, with less than 1% excretion in the feces. Citicolin peaks the first plasma concentration 1 hour after drinking, followed by and the second plasma concentration peak is achieved after 24 hours.
citicolin is metabolized in the intestinal wall and liver. The by -products of external Ciiticolin are formed by hydrolysis in the intestinal wall, choline and cytidine. After absorption, Choline and Cytidine are dispersed throughout the body, into the circulatory system through many biosynthetic paths, and overcome the brain blood barrier and then reinforcement into citicolin in the brain.
Historable pharmacokinetic studies using 14C citicolin shows that citicolin elimination is mainly through the respiratory tract and excreted through urine in 2 stages of showing two plasma concentrations. The first plasma peak concentration decreases rapidly, then slowed down within the next 4 - 10 hours. In the second phase, the concentration of citicolin in blood statues decreases rapidly after 24 hours, then the elimination rate is slower. The sale time of citicolin is 56 hours of respiratory tract and 71 hours for excretion through urine.
Before taking Naciti 500mg Nghe An Pharma tablets treat serious brain damage (3 blisters x 10 tablets)
How to use
Oral drugs.
Dosage
Take 1 - 2 tablets/day or as directed by the physician.
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.
What to do when overdose?
In case of overdose, need for support and symptomatic treatment.
In an emergency, call the 115 emergency center immediately or go to the nearest local health station.
What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.
Side Effects
When using Naciti often has unwanted effects (ADR) very rare
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindicated
Naciti drugs in the following cases:
Be cautious when used
In case of prolonged intracranial hemorrhage, no dosage exceeding 1000 mg of citicolin daily, as it can increase blood flow in the brain.
Use drugs for women during pregnancy and lactation
Not enough data on the use of this drug during pregnancy and during breastfeeding. Do not use drugs for pregnant and lactating women.
The effect of the drug on the ability to drive and operate machinery
Because the drug can cause headaches, dizziness, should be cautious when driving and operating machinery.
Medicinal interaction
Do not coordinate with drugs containing meclofenoxat or Centrofenoxin.
Because the drug increases the effect of Levodopa, it is necessary to be cautious when combining these 2 drugs.
Storage
Leave a cool place, avoid light, temperature below 30⁰C.
To be out of reach of children.
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