Nadifex 180 USP tablets reduce allergic rhinitis, sneeze, nose (1 blister x 10 tablets)

Dosage form Box of 1 blister x 10 tablets
Specifications Fexofenadin HCl

Ingredient

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Composition information	Content
Fexofenadin HCl	180mg

Uses

indications

Nadifex 180 drug is indicated to use tron: mitigate the symptoms that come with allergic rhinitis allergies such as sneezing, nasal nose, nasal congestion, surround itch/throat/throat.

Pharmacokic

Fexofenadin is an antihistamine H1, which does not cause drowsiness. Fexofenadin is a pharmacological activity of terfenadin . Fexofenadin inhibits histamine release from mast cells. Both fiber optical isomers of fexofenadine have the same antihistamine effect. The drug does not pass the bloodstream barrier.

Pharmacokinetics

absorption

Fexofenadin is quickly absorbed into the body after drinking. The drug reaches the peak concentration after taking about 1-3 hours. The average peak concentration is about 494 ng/ml after use 180 mg/time per day.

Distribution

Fexofenadin binds to plasma proteins about 60 - 70%.

Metabolism

Fexofenadin metabolizes negligible (drugs metabolized through the liver about 5% of the total dose).

Elimination

The main excretion path is thought to be excreted through bile, 10% of oral doses are eliminated in the form of unchanged urine.

Before taking Nadifex 180 USP tablets reduce allergic rhinitis, sneeze, nose (1 blister x 10 tablets)

How to use

Take oral water with water, take medicine when hungry.

Dosage

Dosage and medication time for each specific case depending on the prescription of the treating doctor.

Normal dose:

Adults and children over 12 years: 1 tablet 180 mg x 1 time/day.

Not for kidney failure.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

Handling: Using conventional measures to eliminate hemolysis drugs that reduce the concentration of drugs in the blood (1.7%). There is no specific antidote.

What to do when you forget 1 dose? Ignore any of the forgotten dose if it is close to the next dose. Do not use two doses at the same time.

Side Effects

In control clinical studies, the unwanted effect rate in the patient group using fexofenadin is similar to the Placebo. The unwanted effects of the drug are not affected by the dosage, age, gender and race of the patient. When using Nadifex 180, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Neurological: Drowsy, tired, headache , insomnia, dizziness .

digestive: nausea, indigestion.

Other: viral infection (colds, influenza ), dysmenorrhea, upper respiratory infection, itchy throat, fever, cough, otitis media , sinusitis, lung.

Uncommon, 1/1000

Neurological: Fear, sleep disorders, nightmares.

digestive: dry mouth , abdominal pain.

Rare, ADR

DA: Ban, urticaria , itching.

Hypersensitivity reactions: Evana, chest tightness, shortness of breath, redness, anaphylaxis.

Instructions on how to handle ADR

The unwanted effects of the drug are usually mild, only 2.2% of patients have to stop the drug due to the unwanted effects of the drug.

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Nadifex 180 contraindicated drug in the following cases:

Patients with a history of hypersensitivity to any ingredients of the drug.

Patients under 12 years old.

Be cautious when using

Fexofenadin should be used cautiously in elderly people, patients with renal impairment or liver failure.

The ability to drive and operate machinery

The drug is less likely to cause drowsiness, but still need to be cautious when operating machinery or driving train.

Pregnancy

There is no full range of controlled studies on pregnant women. Fexofenadin should only be used for pregnant women when they have considered the benefits and risks for the child.

The period of breastfeeding

There has been no notice that fexofenadin secreted through breast milk. There is no sufficient research on breastfeeding women, so be careful when indicating fexofenadin for breastfeeding women.

Interactive drug

Because the drug can reduce the effect of antacids containing aluminum and magnesi, the drug should be used for about 2 hours apart.

Storage

Store drugs in a dry place, temperatures below 30 ° C, avoiding light.

To be out of reach of children.

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